Advanced search
1 file | 780.05 KB Add to list

Comparison of methods to estimate the affected body surface area and the dosage of topical treatments in psoriasis and atopic dermatitis : the advantage of a picture‐based tool

Reinhart Speeckaert (UGent) , Isabelle Hoorens (UGent) , S Corthals, Liesbeth Delbaere (UGent) , Jo Lambert (UGent) , T. Lesseliers, Sofie Mylle (UGent) , Katia Ongenae (UGent) , Sofie De Schepper (UGent) , L. De Smet, et al.
Author
Organization
Abstract
Background: The accurate determination of the dosage of topical treatments is important given its repercussions on patient adherence and therapeutic efficacy. Up till now, the fingertip unit calculated by the rule of hands is considered the gold standard, although its use is associated with several drawbacks. Objective: To compare different methods to estimate the affected body surface area (BSA) and dosage of topical treatments in atopic dermatitis and psoriasis and investigate its reliability, user-friendliness and timing. Methods: In this study, we compared the reliability of three different methods: (i) the fingertip unit calculated by the 1% hand rule; (ii) a picture-based tool [termed Cutaneous Inflammatory Disease Extent Score (CIDES)]; and (iii) a digital drawing tool. Eleven observers scored 40 patients with psoriasis and eczema to assess the inter-rater and intrarater reliability. Timing was automatically recorded, and user-friendliness was investigated by a questionnaire. Results: An excellent intraclass correlation (ICC) was found for both inter-rater agreement and intrarater agreement for the picture-based tool (ICC = 0.92 and ICC = 0.96, respectively). The ICCs for drawing the area of involvement on a silhouette were 0.89 and 0.93, respectively. Finally, the rule of hands was associated with an increased inter-rater variability although an excellent intrarater agreement was found (ICC = 0.79 and 0.95, respectively). Automated calculation of the amount of topical treatment improved reliability, and CIDES was associated with the least variation. CIDES was considered the preferred method by all observers and was fast to perform (median: 30 s). Conclusion: A picture-based method offered the most advantages (in terms of reliability, speed and user-friendliness) to estimate the affected BSA and calculate the dosage of topical treatments.
Keywords
FINGERTIP UNIT, TACROLIMUS, ADHERENCE, THERAPY, ECZEMA

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 780.05 KB

Citation

Please use this url to cite or link to this publication:

MLA
Speeckaert, Reinhart, et al. “Comparison of Methods to Estimate the Affected Body Surface Area and the Dosage of Topical Treatments in Psoriasis and Atopic Dermatitis : The Advantage of a Picture‐based Tool.” JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, vol. 33, no. 9, 2019, pp. 1726–32, doi:10.1111/jdv.15726.
APA
Speeckaert, R., Hoorens, I., Corthals, S., Delbaere, L., Lambert, J., Lesseliers, T., … van Geel, N. (2019). Comparison of methods to estimate the affected body surface area and the dosage of topical treatments in psoriasis and atopic dermatitis : the advantage of a picture‐based tool. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 33(9), 1726–1732. https://doi.org/10.1111/jdv.15726
Chicago author-date
Speeckaert, Reinhart, Isabelle Hoorens, S Corthals, Liesbeth Delbaere, Jo Lambert, T. Lesseliers, Sofie Mylle, et al. 2019. “Comparison of Methods to Estimate the Affected Body Surface Area and the Dosage of Topical Treatments in Psoriasis and Atopic Dermatitis : The Advantage of a Picture‐based Tool.” JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 33 (9): 1726–32. https://doi.org/10.1111/jdv.15726.
Chicago author-date (all authors)
Speeckaert, Reinhart, Isabelle Hoorens, S Corthals, Liesbeth Delbaere, Jo Lambert, T. Lesseliers, Sofie Mylle, Katia Ongenae, Sofie De Schepper, L. De Smet, Marijn Speeckaert, and Nanja van Geel. 2019. “Comparison of Methods to Estimate the Affected Body Surface Area and the Dosage of Topical Treatments in Psoriasis and Atopic Dermatitis : The Advantage of a Picture‐based Tool.” JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 33 (9): 1726–1732. doi:10.1111/jdv.15726.
Vancouver
1.
Speeckaert R, Hoorens I, Corthals S, Delbaere L, Lambert J, Lesseliers T, et al. Comparison of methods to estimate the affected body surface area and the dosage of topical treatments in psoriasis and atopic dermatitis : the advantage of a picture‐based tool. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2019;33(9):1726–32.
IEEE
[1]
R. Speeckaert et al., “Comparison of methods to estimate the affected body surface area and the dosage of topical treatments in psoriasis and atopic dermatitis : the advantage of a picture‐based tool,” JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, vol. 33, no. 9, pp. 1726–1732, 2019.
@article{8636547,
  abstract     = {{Background: The accurate determination of the dosage of topical treatments is important given its repercussions on patient adherence and therapeutic efficacy. Up till now, the fingertip unit calculated by the rule of hands is considered the gold standard, although its use is associated with several drawbacks.
Objective: To compare different methods to estimate the affected body surface area (BSA) and dosage of topical treatments in atopic dermatitis and psoriasis and investigate its reliability, user-friendliness and timing.
Methods: In this study, we compared the reliability of three different methods: (i) the fingertip unit calculated by the 1% hand rule; (ii) a picture-based tool [termed Cutaneous Inflammatory Disease Extent Score (CIDES)]; and (iii) a digital drawing tool. Eleven observers scored 40 patients with psoriasis and eczema to assess the inter-rater and intrarater reliability. Timing was automatically recorded, and user-friendliness was investigated by a questionnaire.
Results: An excellent intraclass correlation (ICC) was found for both inter-rater agreement and intrarater agreement for the picture-based tool (ICC = 0.92 and ICC = 0.96, respectively). The ICCs for drawing the area of involvement on a silhouette were 0.89 and 0.93, respectively. Finally, the rule of hands was associated with an increased inter-rater variability although an excellent intrarater agreement was found (ICC = 0.79 and 0.95, respectively). Automated calculation of the amount of topical treatment improved reliability, and CIDES was associated with the least variation. CIDES was considered the preferred method by all observers and was fast to perform (median: 30 s).
Conclusion: A picture-based method offered the most advantages (in terms of reliability, speed and user-friendliness) to estimate the affected BSA and calculate the dosage of topical treatments.}},
  author       = {{Speeckaert, Reinhart and Hoorens, Isabelle and Corthals, S and Delbaere, Liesbeth and Lambert, Jo and Lesseliers, T. and Mylle, Sofie and Ongenae, Katia and De Schepper, Sofie and De Smet, L. and Speeckaert, Marijn and van Geel, Nanja}},
  issn         = {{0926-9959}},
  journal      = {{JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY}},
  keywords     = {{FINGERTIP UNIT,TACROLIMUS,ADHERENCE,THERAPY,ECZEMA}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{1726--1732}},
  title        = {{Comparison of methods to estimate the affected body surface area and the dosage of topical treatments in psoriasis and atopic dermatitis : the advantage of a picture‐based tool}},
  url          = {{http://dx.doi.org/10.1111/jdv.15726}},
  volume       = {{33}},
  year         = {{2019}},
}

Altmetric
View in Altmetric
Web of Science
Times cited: