Advanced search
1 file | 338.65 KB Add to list

Risk factors for neonatal brachial plexus palsy : a systematic review and meta‐analysis

Ruth Van der Looven (UGent) , Laura Le Roy (UGent) , Emma Tanghe, Bieke Samijn (UGent) , Ellen Roets (UGent) , Nele Pauwels (UGent) , Ellen Deschepper (UGent) , Martine De Muynck (UGent) , Guy Vingerhoets (UGent) and Christine Van den Broeck (UGent)
Author
Organization
Abstract
Aim To provide a comprehensive update on the most prevalent, significant risk factors for neonatal brachial plexus palsy (NBPP). Method Cochrane CENTRAL, MEDLINE, Web of Science, Embase, and ClinicalTrials.gov were searched for relevant publications up to March 2019. Studies assessing risk factors of NBPP in relation to typically developing comparison individuals were included. Meta-analysis was performed for the five most significant risk factors, on the basis of the PRISMA statement and MOOSE guidelines. Pooled odds ratios (ORs), 95% confidence intervals (CIs), and across-study heterogeneity (I-2) were reported. Reporting bias and quality of evidence was rated. In addition, we assessed the incidence of NBPP. Results Twenty-two observational studies with a total sample size of 29 419 037 live births were selected. Significant risk factors included shoulder dystocia (OR 115.27; 95% CI 81.35-163.35; I-2=92%), macrosomia (OR 9.75; 95% CI 8.29-11.46; I-2=70%), (gestational) diabetes (OR 5.33; 95% CI 3.77-7.55; I-2=59%), instrumental delivery (OR 3.8; 95% CI 2.77-5.23; I-2=77%), and breech delivery (OR 2.49; 95% CI 1.67-3.7; I-2=70%). Caesarean section appeared as a protective factor (OR 0.13; 95% CI 0.11-0.16; I-2=41%). The pooled overall incidence of NBPP was 1.74 per 1000 live births. It has decreased in recent years. Interpretation The incidence of NBPP is decreasing. Shoulder dystocia, macrosomia, maternal diabetes, instrumental delivery, and breech delivery are risk factors for NBPP. Caesarean section appears as a protective factor. What this paper adds The overall incidence of neonatal brachial plexus palsy is 1.74 per 1000 live births. The incidence has declined significantly. Shoulder dystocia, macrosomia, maternal diabetes, instrumental delivery, and breech delivery are the main risk factors. Prevention is difficult owing to unpredictability and often labour-related risk.
Keywords
GESTATIONAL DIABETES-MELLITUS, FRANK BREECH PRESENTATION, PLANNED CESAREAN-SECTION, SHOULDER DYSTOCIA, FETAL MACROSOMIA, BIRTH PALSY, MICROSURGICAL RECONSTRUCTION, RANDOMIZED MANAGEMENT, DEVELOPMENTAL APRAXIA, VAGINAL DELIVERY

Downloads

  • (...).pdf
    • full text (Published version)
    • |
    • UGent only
    • |
    • PDF
    • |
    • 338.65 KB

Citation

Please use this url to cite or link to this publication:

MLA
Van der Looven, Ruth, et al. “Risk Factors for Neonatal Brachial Plexus Palsy : A Systematic Review and Meta‐analysis.” DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, vol. 62, no. 6, 2020, pp. 673–83, doi:10.1111/dmcn.14381.
APA
Van der Looven, R., Le Roy, L., Tanghe, E., Samijn, B., Roets, E., Pauwels, N., … Van den Broeck, C. (2020). Risk factors for neonatal brachial plexus palsy : a systematic review and meta‐analysis. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 62(6), 673–683. https://doi.org/10.1111/dmcn.14381
Chicago author-date
Van der Looven, Ruth, Laura Le Roy, Emma Tanghe, Bieke Samijn, Ellen Roets, Nele Pauwels, Ellen Deschepper, Martine De Muynck, Guy Vingerhoets, and Christine Van den Broeck. 2020. “Risk Factors for Neonatal Brachial Plexus Palsy : A Systematic Review and Meta‐analysis.” DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 62 (6): 673–83. https://doi.org/10.1111/dmcn.14381.
Chicago author-date (all authors)
Van der Looven, Ruth, Laura Le Roy, Emma Tanghe, Bieke Samijn, Ellen Roets, Nele Pauwels, Ellen Deschepper, Martine De Muynck, Guy Vingerhoets, and Christine Van den Broeck. 2020. “Risk Factors for Neonatal Brachial Plexus Palsy : A Systematic Review and Meta‐analysis.” DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY 62 (6): 673–683. doi:10.1111/dmcn.14381.
Vancouver
1.
Van der Looven R, Le Roy L, Tanghe E, Samijn B, Roets E, Pauwels N, et al. Risk factors for neonatal brachial plexus palsy : a systematic review and meta‐analysis. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2020;62(6):673–83.
IEEE
[1]
R. Van der Looven et al., “Risk factors for neonatal brachial plexus palsy : a systematic review and meta‐analysis,” DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, vol. 62, no. 6, pp. 673–683, 2020.
@article{8635301,
  abstract     = {{Aim To provide a comprehensive update on the most prevalent, significant risk factors for neonatal brachial plexus palsy (NBPP).

Method Cochrane CENTRAL, MEDLINE, Web of Science, Embase, and ClinicalTrials.gov were searched for relevant publications up to March 2019. Studies assessing risk factors of NBPP in relation to typically developing comparison individuals were included. Meta-analysis was performed for the five most significant risk factors, on the basis of the PRISMA statement and MOOSE guidelines. Pooled odds ratios (ORs), 95% confidence intervals (CIs), and across-study heterogeneity (I-2) were reported. Reporting bias and quality of evidence was rated. In addition, we assessed the incidence of NBPP.

Results Twenty-two observational studies with a total sample size of 29 419 037 live births were selected. Significant risk factors included shoulder dystocia (OR 115.27; 95% CI 81.35-163.35; I-2=92%), macrosomia (OR 9.75; 95% CI 8.29-11.46; I-2=70%), (gestational) diabetes (OR 5.33; 95% CI 3.77-7.55; I-2=59%), instrumental delivery (OR 3.8; 95% CI 2.77-5.23; I-2=77%), and breech delivery (OR 2.49; 95% CI 1.67-3.7; I-2=70%). Caesarean section appeared as a protective factor (OR 0.13; 95% CI 0.11-0.16; I-2=41%). The pooled overall incidence of NBPP was 1.74 per 1000 live births. It has decreased in recent years.

Interpretation The incidence of NBPP is decreasing. Shoulder dystocia, macrosomia, maternal diabetes, instrumental delivery, and breech delivery are risk factors for NBPP. Caesarean section appears as a protective factor.

What this paper adds

The overall incidence of neonatal brachial plexus palsy is 1.74 per 1000 live births.

The incidence has declined significantly.

Shoulder dystocia, macrosomia, maternal diabetes, instrumental delivery, and breech delivery are the main risk factors.

Prevention is difficult owing to unpredictability and often labour-related risk.}},
  author       = {{Van der Looven, Ruth and Le Roy, Laura and Tanghe, Emma and Samijn, Bieke and Roets, Ellen and Pauwels, Nele and Deschepper, Ellen and De Muynck, Martine and Vingerhoets, Guy and Van den Broeck, Christine}},
  issn         = {{0012-1622}},
  journal      = {{DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY}},
  keywords     = {{GESTATIONAL DIABETES-MELLITUS,FRANK BREECH PRESENTATION,PLANNED CESAREAN-SECTION,SHOULDER DYSTOCIA,FETAL MACROSOMIA,BIRTH PALSY,MICROSURGICAL RECONSTRUCTION,RANDOMIZED MANAGEMENT,DEVELOPMENTAL APRAXIA,VAGINAL DELIVERY}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{673--683}},
  title        = {{Risk factors for neonatal brachial plexus palsy : a systematic review and meta‐analysis}},
  url          = {{http://dx.doi.org/10.1111/dmcn.14381}},
  volume       = {{62}},
  year         = {{2020}},
}

Altmetric
View in Altmetric
Web of Science
Times cited: