@article{8632121,
  abstract     = {{The mammalian brain is composed of densely connected and interacting regions, which form structural and functional networks. An improved understanding of the structure-function relation is crucial to understand the structural underpinnings of brain function and brain plasticity after injury. It is currently unclear how functional connectivity strength relates to structural connectivity strength. We obtained an overview of recent papers that report on correspondences between quantitative functional and structural connectivity measures in the mammalian brain. We included network studies in which functional connectivity was measured with resting-state fMRI, and structural connectivity with either diffusion-weighted MRI or neuronal tract tracers. Twenty-seven of the 28 included studies showed a positive structure-function relationship. Large inter-study variations were found comparing functional connectivity strength with either quantitative diffusion-based (correlation coefficient (r) ranges: 0.18-0.82) or neuronal tracer-based structural connectivity measures (r = 0.24-0.74). Two functional datasets demonstrated lower structure-function correlations with neuronal tracer-based (r = 0.22 and r = 0.30) than with diffusion-based measures (r = 0.49 and r = 0.65). The robust positive quantitative structure-function relationship supports the hypothesis that structural connectivity provides the hardware from which functional connectivity emerges. However, methodological differences between the included studies complicate the comparison across studies, which emphasize the need for validation and standardization in brain structure-function studies.}},
  author       = {{Straathof, Milou and Sinke, Michel RT and Dijkhuizen, Rick M and Otte, Willem M and Buitelaar, Jan and de Ruiter, Saskia and Naaijen, Jilly and Akkermans, Sophie and Mennes, Maarten and Zwiers, Marcel and Ilbegi, Shahrzad and Hennissen, Leonie and Glennon, Jeffrey and van de Vondervoort, Ilse and Kapusta, Katarzyna and Bielczyk, Natalia and Amiri, Houshang and Havenith, Martha and Franke, Barbara and Poelmans, Geert and Bralten, Janita and Heskes, Tom and Sokolova, Elena and Groot, Perry and Williams, Steven and Murphy, Declan and Lythgoe, David and Bruchhage, Muriel and Dud, Iulia and Voinescu, Bogdan and Dittmann, Ralf and Banaschewski, Tobias and Brandeis, Daniel and Mechler, Konstantin and Berg, Ruth and Wolf, Isabella and Haege, Alexander and Landauer, Michael and Hohmann, Sarah and Boecker-Schlier, Regina and Ruff, Matthias and Dijkhuizen, Rick and Blezer, Erwin and Straathof, Milou and van der Marel, Kajo and Pullens, Pim and Mol, Wouter and van der Toorn, Annette and Otte, Willem and van Heijningen, Caroline and Durston, Sarah and Mensen, Vincent and Oranje, Bob and Mandl, Rene and Joel, Daphna and Cryan, John and Petryshen, Tracey and Pauls, David and Saito, Mai and Heckman, Angelique and Bahn, Sabine and Schwalber, Ameli and Florea, Ioana}},
  issn         = {{0271-678X}},
  journal      = {{JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM}},
  keywords     = {{CORTICAL CONNECTOME RECONSTRUCTION,DIFFUSION MRI TRACTOGRAPHY,WHITE-MATTER,DEFAULT-MODE,MOUSE-BRAIN,GRANGER CAUSALITY,ANALYTIC,MEASURES,RESTING-BRAIN,RICH CLUB,STATE,Brain,diffusion magnetic resonance imaging,functional magnetic,resonance imaging,network connectivity,neuronal tract-tracers}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{189--209}},
  title        = {{A systematic review on the quantitative relationship between structural and functional network connectivity strength in mammalian brains}},
  url          = {{http://doi.org/10.1177/0271678X18809547}},
  volume       = {{39}},
  year         = {{2019}},
}

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