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Spatiotemporal electrochemical sensing in a smart contact lens

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Abstract
An electrochemical smart contact lens (ESCL) capable of real-speed spatiotemporal electrochemical sensing across the surface of the eye is demonstrated. Four microelectrode arrays, each comprising 33 gold microdiscs of 30 μm diameter, and a distributed common gold counter electrode, are integrated into a soft smart contact lens platform based on polyimide and thermoplastic polyurethane. Using a novel fast-switching chronoamperometric method, an electrochemical ‘video’ of concentration variation in a model eye under flow conditions is produced, in which the introduction, progress, mixing and drainage of fluid of varying concentration can be observed. The device builds on previous work towards a platform suitable for clinical use and has proven to be robust under expected use conditions, with sensing performance remaining unchanged after thermoforming and repeated mechanical deformation. This work represents a significant step forward in ESCL design, and constitutes sig- nificant progress towards a technology with real clinical utility.
Keywords
Instrumentation, Electrical and Electronic Engineering, Materials Chemistry, Electronic, Optical and Magnetic Materials, Surfaces, Coatings and Films, Condensed Matter Physics, Metals and Alloys, SENSORS, BIOCOMPATIBILITY, PERFORMANCE, POLYIMIDES, ARRAYS, LIGHT

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Citation

Please use this url to cite or link to this publication:

MLA
Donora, Matthew, et al. “Spatiotemporal Electrochemical Sensing in a Smart Contact Lens.” SENSORS AND ACTUATORS B-CHEMICAL, vol. 303, 2020.
APA
Donora, M., Vasquez Quintero, A. F., De Smet, H., & Underwood, I. (2020). Spatiotemporal electrochemical sensing in a smart contact lens. SENSORS AND ACTUATORS B-CHEMICAL, 303.
Chicago author-date
Donora, Matthew, Andrés Felipe Vasquez Quintero, Herbert De Smet, and Ian Underwood. 2020. “Spatiotemporal Electrochemical Sensing in a Smart Contact Lens.” SENSORS AND ACTUATORS B-CHEMICAL 303.
Chicago author-date (all authors)
Donora, Matthew, Andrés Felipe Vasquez Quintero, Herbert De Smet, and Ian Underwood. 2020. “Spatiotemporal Electrochemical Sensing in a Smart Contact Lens.” SENSORS AND ACTUATORS B-CHEMICAL 303.
Vancouver
1.
Donora M, Vasquez Quintero AF, De Smet H, Underwood I. Spatiotemporal electrochemical sensing in a smart contact lens. SENSORS AND ACTUATORS B-CHEMICAL. 2020;303.
IEEE
[1]
M. Donora, A. F. Vasquez Quintero, H. De Smet, and I. Underwood, “Spatiotemporal electrochemical sensing in a smart contact lens,” SENSORS AND ACTUATORS B-CHEMICAL, vol. 303, 2020.
@article{8632034,
  abstract     = {An electrochemical smart contact lens (ESCL) capable of real-speed spatiotemporal electrochemical sensing
across the surface of the eye is demonstrated. Four microelectrode arrays, each comprising 33 gold microdiscs of
30 μm diameter, and a distributed common gold counter electrode, are integrated into a soft smart contact lens
platform based on polyimide and thermoplastic polyurethane. Using a novel fast-switching chronoamperometric
method, an electrochemical ‘video’ of concentration variation in a model eye under flow conditions is produced,
in which the introduction, progress, mixing and drainage of fluid of varying concentration can be observed. The
device builds on previous work towards a platform suitable for clinical use and has proven to be robust under
expected use conditions, with sensing performance remaining unchanged after thermoforming and repeated
mechanical deformation. This work represents a significant step forward in ESCL design, and constitutes sig-
nificant progress towards a technology with real clinical utility.},
  articleno    = {127203},
  author       = {Donora, Matthew and Vasquez Quintero, Andrés Felipe and De Smet, Herbert and Underwood, Ian},
  issn         = {0925-4005},
  journal      = {SENSORS AND ACTUATORS B-CHEMICAL},
  keywords     = {Instrumentation,Electrical and Electronic Engineering,Materials Chemistry,Electronic,Optical and Magnetic Materials,Surfaces,Coatings and Films,Condensed Matter Physics,Metals and Alloys,SENSORS,BIOCOMPATIBILITY,PERFORMANCE,POLYIMIDES,ARRAYS,LIGHT},
  language     = {eng},
  pages        = {10},
  title        = {Spatiotemporal electrochemical sensing in a smart contact lens},
  url          = {http://dx.doi.org/10.1016/j.snb.2019.127203},
  volume       = {303},
  year         = {2020},
}

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