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Spatiotemporal electrochemical sensing in a smart contact lens

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Abstract
An electrochemical smart contact lens (ESCL) capable of real-speed spatiotemporal electrochemical sensing across the surface of the eye is demonstrated. Four microelectrode arrays, each comprising 33 gold microdiscs of 30 μm diameter, and a distributed common gold counter electrode, are integrated into a soft smart contact lens platform based on polyimide and thermoplastic polyurethane. Using a novel fast-switching chronoamperometric method, an electrochemical ‘video’ of concentration variation in a model eye under flow conditions is produced, in which the introduction, progress, mixing and drainage of fluid of varying concentration can be observed. The device builds on previous work towards a platform suitable for clinical use and has proven to be robust under expected use conditions, with sensing performance remaining unchanged after thermoforming and repeated mechanical deformation. This work represents a significant step forward in ESCL design, and constitutes sig- nificant progress towards a technology with real clinical utility.
Keywords
Instrumentation, Electrical and Electronic Engineering, Materials Chemistry, Electronic, Optical and Magnetic Materials, Surfaces, Coatings and Films, Condensed Matter Physics, Metals and Alloys

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Citation

Please use this url to cite or link to this publication:

MLA
Donora, Matthew, et al. “Spatiotemporal Electrochemical Sensing in a Smart Contact Lens.” Sensors and Actuators B: Chemical, vol. 303, 2020.
APA
Donora, M., Vasquez Quintero, A. F., De Smet, H., & Underwood, I. (2020). Spatiotemporal electrochemical sensing in a smart contact lens. Sensors and Actuators B: Chemical, 303.
Chicago author-date
Donora, Matthew, Andrés Felipe Vasquez Quintero, Herbert De Smet, and Ian Underwood. 2020. “Spatiotemporal Electrochemical Sensing in a Smart Contact Lens.” Sensors and Actuators B: Chemical 303.
Chicago author-date (all authors)
Donora, Matthew, Andrés Felipe Vasquez Quintero, Herbert De Smet, and Ian Underwood. 2020. “Spatiotemporal Electrochemical Sensing in a Smart Contact Lens.” Sensors and Actuators B: Chemical 303.
Vancouver
1.
Donora M, Vasquez Quintero AF, De Smet H, Underwood I. Spatiotemporal electrochemical sensing in a smart contact lens. Sensors and Actuators B: Chemical. 2020;303.
IEEE
[1]
M. Donora, A. F. Vasquez Quintero, H. De Smet, and I. Underwood, “Spatiotemporal electrochemical sensing in a smart contact lens,” Sensors and Actuators B: Chemical, vol. 303, 2020.
@article{8632034,
  abstract     = {An electrochemical smart contact lens (ESCL) capable of real-speed spatiotemporal electrochemical sensing
across the surface of the eye is demonstrated. Four microelectrode arrays, each comprising 33 gold microdiscs of
30 μm diameter, and a distributed common gold counter electrode, are integrated into a soft smart contact lens
platform based on polyimide and thermoplastic polyurethane. Using a novel fast-switching chronoamperometric
method, an electrochemical ‘video’ of concentration variation in a model eye under flow conditions is produced,
in which the introduction, progress, mixing and drainage of fluid of varying concentration can be observed. The
device builds on previous work towards a platform suitable for clinical use and has proven to be robust under
expected use conditions, with sensing performance remaining unchanged after thermoforming and repeated
mechanical deformation. This work represents a significant step forward in ESCL design, and constitutes sig-
nificant progress towards a technology with real clinical utility.},
  articleno    = {127203},
  author       = {Donora, Matthew and Vasquez Quintero, Andrés Felipe and De Smet, Herbert and Underwood, Ian},
  issn         = {0925-4005},
  journal      = {Sensors and Actuators B: Chemical},
  keywords     = {Instrumentation,Electrical and Electronic Engineering,Materials Chemistry,Electronic,Optical and Magnetic Materials,Surfaces,Coatings and Films,Condensed Matter Physics,Metals and Alloys},
  language     = {eng},
  title        = {Spatiotemporal electrochemical sensing in a smart contact lens},
  url          = {http://dx.doi.org/10.1016/j.snb.2019.127203},
  volume       = {303},
  year         = {2020},
}

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