Advanced search
1 file | 1.46 MB Add to list

Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study

(2019) EUROPEAN JOURNAL OF NUTRITION. 58(5). p.2051-2065
Author
Organization
Abstract
Aim: To assess if a healthy diet might attenuate the positive sedentary-inflammation relation, whereas an unhealthy diet may increase the effect of sedentary behaviors on inflammatory biomarkers. Methods: In 618 adolescents (13-17 years) of the European HELENA study, data were available on body composition, a set of inflammation markers, and food intake assessed by a self-administered computerized 24h dietary recall for 2 days. A 9-point Mediterranean diet score and an antioxidant-rich diet z-score were used as dietary indices and tested as moderators. A set of low-grade inflammatory characteristics was used as outcome: several cytokines in an inflammatory ratio (IL-6, IL-10, TNF-alpha, TGF beta-1), C-reactive protein, three cell-adhesion molecules (sVCAM-1, sICAM-1, sE-selectin), three cardiovascular risk markers (GGT, ALT, homocysteine) and three immune cell types (white blood cells, lymphocytes, CD3). Sedentary behaviors were self-reported and analyzed as total screen time. Multiple linear regression analyses tested moderation by diet in the sedentary behaviors-inflammation association adjusted for age, sex, country, adiposity (sum of six skinfolds), parental education, and socio-economic status. Results: Both diet scores, Mediterranean and antioxidant-rich diet, were significant protective moderators in the effect of sedentary behaviors on alanine-transaminase enzyme (P=0.014; P=0.027), and on the pro/anti-inflammatory cytokine ratio (P=0.001; P=0.004), but not on other inflammatory parameters. Conclusion: A higher adherence to the Mediterranean diet or an antioxidant-rich diet may attenuate the onset of oxidative stress signs associated by sedentary behaviors, whereas a poor diet seems to increase inflammation.
Keywords
POLYUNSATURATED FATTY-ACIDS, HEALTHY LIFE-STYLE, PHYSICAL-ACTIVITY, EUROPEAN ADOLESCENTS, MEDITERRANEAN DIET, LIVER-DISEASE, ALANINE, AMINOTRANSFERASE, BODY-FAT, INSULIN-RESISTANCE, INCREASED RISK, Sedentary behavior, Mediterranean diet, Low-grade inflammation, Moderation, Adolescents, HELENA study

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 1.46 MB

Citation

Please use this url to cite or link to this publication:

MLA
Arouca, Aline, et al. “Diet as a Moderator in the Association of Sedentary Behaviors with Inflammatory Biomarkers among Adolescents in the HELENA Study.” EUROPEAN JOURNAL OF NUTRITION, vol. 58, no. 5, 2019, pp. 2051–65.
APA
Arouca, A., Santaliestra-Pasias, A. M., Moreno, L. A., Marcos, A., Widhalm, K., Molnars, D., … HELENA, S. G. (2019). Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study. EUROPEAN JOURNAL OF NUTRITION, 58(5), 2051–2065.
Chicago author-date
Arouca, Aline, Alba M Santaliestra-Pasias, Luis A Moreno, Ascension Marcos, Kurt Widhalm, Denes Molnars, Yannis Manios, et al. 2019. “Diet as a Moderator in the Association of Sedentary Behaviors with Inflammatory Biomarkers among Adolescents in the HELENA Study.” EUROPEAN JOURNAL OF NUTRITION 58 (5): 2051–65.
Chicago author-date (all authors)
Arouca, Aline, Alba M Santaliestra-Pasias, Luis A Moreno, Ascension Marcos, Kurt Widhalm, Denes Molnars, Yannis Manios, Frederic Gottrand, Anthony Kafatos, Mathilde Kersting, Michael Sjostrom, Angel Gutierrez Sainzu, Marika Ferrari, Inge Huybrechts, Marcela Gonzalez-Gross, Maria Forsner, Stefaan De Henauw, Nathalie Michels, Chantal Gilbert, Christian Libersa, Sara Castello, Michael Sjostrom, Denes Molnar, Jean Dallongeville, Gunnar Hall, Lea Maes, Luca Scalfi, Pilar Melendez, Jose A Casajus, Jesus Fleta, Gerardo Rodriguez, Concepcion Tomas, Maria I Mesana, German Vicente-Rodriguez, Adoracion Villarroya, Carlos M Gil, Ignacio Ara, Juan Fernandez Alvira, Gloria Bueno, Olga Bueno, Juan F Leon, Jesus Ma Garagorri, Idoia Labayen, Silvia Bel, Luis A Gracia Marco, Theodora Mouratidou, Alba Santaliestra-Pasias, Iris Iglesia, Esther Gonzalez-Gil, Pilar De Miguel-Etayo, Cristina Julian, Mary Miguel-Berges, Isabel Iguacel, Azahara Ruperez, Julia Warnberg, Esther Nova, Sonia Gomez, Ligia Esperanza Diaz, Javier Romeo, Ana Veses, Belen Zapatera, Tamara Pozo, David Martinez, Laurent Beghin, Catalina Iliescu, Juliana Von Berlepsch, Wolfgang Sichert-Hellert, Ellen Koeppen, Eva Erhardt, Katalin Csernus, Katalin Torok, Szilvia Bokor, Angster Angster, Eniko Nagy, Orsolya Kovacs, Judit Repasi, Caroline Codrington, Maria Plada, Angeliki Papadaki, Katerina Sarri, Anna Viskadourou, Christos Hatzis, Michael Kiriakakis, George Tsibinos, Constantine Vardavas, Manolis Sbokos, Eva Protoyeraki, Maria Fasoulaki, Peter Stehle, Klaus Pietrzik, Christina Breidenassel, Andre Spinneker, Jasmin Al-Tahan, Miriam Segoviano, Anke Berchtold, Christine Bierschbach, Erika Blatzheim, Adelheid Schuch, Petra Pickert, Manuel J Castillo, Angel Gutierrez, Francisco B Ortega, Jonatan R Ruiz, Enrique G Artero, Vanesa Espana, David Jimenez-Pavon, Palma Chilton, Cristobal Sanchez-Munoz, Magdalena Cuenca, Davide Arcella, Elena Azzini, Emma Barrison, Noemi Bevilacqua, Pasquale Buonocore, Giovina Catasta, Laura Censi, Donatella Ciarapica, Paola D’Acapito, Myriam Galfo, Cinzia Le Donne, Catherine Leclercq, Giuseppe Maiani, Beatrice Mauro, Lorenza Mistura, Antonella Pasquali, Raffaela Piccinelli, Angela Polito, Romana Roccaldo, Raffaella Spada, Stefania Sette, Maria Zaccaria, Paola Vitaglione, Concetta Montagnese, Ilse De Bourdeaudhuij, Tineke De Vriendt, Christophe Matthys, Carine Vereecken, Mieke de Maeyer, Charlene Ottevaere, Katharina Phillipp, Sabine Dietrich, Birgit Kubelka Marion Boriss-Riedl, Eva Grammatikaki, Zoi Bouloubasi, Tina Louisa Cook, Sofia Eleutheriou, Orsalia Consta, George Moschonis, Ioanna Katsaroli, George Kraniou, Stab Papoutsou, Despoina Keke, Ioanna Petraki, Elena Bellou, Sofia Tanagra, Kostalenia Kallianoti, Dionysia Argyropoulou, Stamatoula Tsikrika, Christos Karaiskos, Aline Meirhaeghe, Maria Hagstromer, Anita Hurtig Wenntof, Lena Hallstrom, Emma Patterson, Lydia Kwak, Nico Rizzo, Jackie Sanchez-Motero, Elena Pico, Maite Navarro, Blanca Viadel, Jose Enrique Carreres, Gema Merino, Rosa Sanjuan, Maria Lorente, Maria Jose Sanchez, Sarah Thomas, Elaine Allchurch, Peter Burgess, Annika Astrom, Anna Sverken, Agneta Broberg, Annick Masson, Claire Lehoux, Pascal Brabant, Philippe Pate, Laurence Fontaine, Andras Sebok, Tunde Kuti, Adrienn Hegyi, Cristina Maldonado, Ana Llorente, Emilio Garcia, Holger von Fircks, Marianne Lilja Hallberg, Maria Messerer, Mats Larsson, Helena Fredriksson, Viola Adamsson, Ingmar Borjesson, Laura Fernandez, Laura Smillie, Josephine Wills, Raquel Pedrero-Chamizo, Agustin Melendez, Jara Valtuena, Ulrike Albers, Pedro J Benito, Juan Jose Gomez Lorente, David Canada, Alejandro Urzanqui, Rosa Maria Torres, Paloma Navarro, and Study Group HELENA. 2019. “Diet as a Moderator in the Association of Sedentary Behaviors with Inflammatory Biomarkers among Adolescents in the HELENA Study.” EUROPEAN JOURNAL OF NUTRITION 58 (5): 2051–2065.
Vancouver
1.
Arouca A, Santaliestra-Pasias AM, Moreno LA, Marcos A, Widhalm K, Molnars D, et al. Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study. EUROPEAN JOURNAL OF NUTRITION. 2019;58(5):2051–65.
IEEE
[1]
A. Arouca et al., “Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study,” EUROPEAN JOURNAL OF NUTRITION, vol. 58, no. 5, pp. 2051–2065, 2019.
@article{8630950,
  abstract     = {Aim: To assess if a healthy diet might attenuate the positive sedentary-inflammation relation, whereas an unhealthy diet may increase the effect of sedentary behaviors on inflammatory biomarkers. 
Methods: In 618 adolescents (13-17 years) of the European HELENA study, data were available on body composition, a set of inflammation markers, and food intake assessed by a self-administered computerized 24h dietary recall for 2 days. A 9-point Mediterranean diet score and an antioxidant-rich diet z-score were used as dietary indices and tested as moderators. A set of low-grade inflammatory characteristics was used as outcome: several cytokines in an inflammatory ratio (IL-6, IL-10, TNF-alpha, TGF beta-1), C-reactive protein, three cell-adhesion molecules (sVCAM-1, sICAM-1, sE-selectin), three cardiovascular risk markers (GGT, ALT, homocysteine) and three immune cell types (white blood cells, lymphocytes, CD3). Sedentary behaviors were self-reported and analyzed as total screen time. Multiple linear regression analyses tested moderation by diet in the sedentary behaviors-inflammation association adjusted for age, sex, country, adiposity (sum of six skinfolds), parental education, and socio-economic status. 
Results: Both diet scores, Mediterranean and antioxidant-rich diet, were significant protective moderators in the effect of sedentary behaviors on alanine-transaminase enzyme (P=0.014; P=0.027), and on the pro/anti-inflammatory cytokine ratio (P=0.001; P=0.004), but not on other inflammatory parameters. 
Conclusion: A higher adherence to the Mediterranean diet or an antioxidant-rich diet may attenuate the onset of oxidative stress signs associated by sedentary behaviors, whereas a poor diet seems to increase inflammation.},
  author       = {Arouca, Aline and Santaliestra-Pasias, Alba M and Moreno, Luis A and Marcos, Ascension and Widhalm, Kurt and Molnars, Denes and Manios, Yannis and Gottrand, Frederic and Kafatos, Anthony and Kersting, Mathilde and Sjostrom, Michael and Gutierrez Sainzu, Angel and Ferrari, Marika and Huybrechts, Inge and Gonzalez-Gross, Marcela and Forsner, Maria and De Henauw, Stefaan and Michels, Nathalie and Gilbert, Chantal and Libersa, Christian and Castello, Sara and Sjostrom, Michael and Molnar, Denes and Dallongeville, Jean and Hall, Gunnar and Maes, Lea and Scalfi, Luca and Melendez, Pilar and Casajus, Jose A and Fleta, Jesus and Rodriguez, Gerardo and Tomas, Concepcion and Mesana, Maria I and Vicente-Rodriguez, German and Villarroya, Adoracion and Gil, Carlos M and Ara, Ignacio and Fernandez Alvira, Juan and Bueno, Gloria and Bueno, Olga and Leon, Juan F and Garagorri, Jesus Ma and Labayen, Idoia and Bel, Silvia and Marco, Luis A Gracia and Mouratidou, Theodora and Santaliestra-Pasias, Alba and Iglesia, Iris and Gonzalez-Gil, Esther and De Miguel-Etayo, Pilar and Julian, Cristina and Miguel-Berges, Mary and Iguacel, Isabel and Ruperez, Azahara and Warnberg, Julia and Nova, Esther and Gomez, Sonia and Diaz, Ligia Esperanza and Romeo, Javier and Veses, Ana and Zapatera, Belen and Pozo, Tamara and Martinez, David and Beghin, Laurent and Iliescu, Catalina and Von Berlepsch, Juliana and Sichert-Hellert, Wolfgang and Koeppen, Ellen and Erhardt, Eva and Csernus, Katalin and Torok, Katalin and Bokor, Szilvia and Angster, Angster and Nagy, Eniko and Kovacs, Orsolya and Repasi, Judit and Codrington, Caroline and Plada, Maria and Papadaki, Angeliki and Sarri, Katerina and Viskadourou, Anna and Hatzis, Christos and Kiriakakis, Michael and Tsibinos, George and Vardavas, Constantine and Sbokos, Manolis and Protoyeraki, Eva and Fasoulaki, Maria and Stehle, Peter and Pietrzik, Klaus and Breidenassel, Christina and Spinneker, Andre and Al-Tahan, Jasmin and Segoviano, Miriam and Berchtold, Anke and Bierschbach, Christine and Blatzheim, Erika and Schuch, Adelheid and Pickert, Petra and Castillo, Manuel J and Gutierrez, Angel and Ortega, Francisco B and Ruiz, Jonatan R and Artero, Enrique G and Espana, Vanesa and Jimenez-Pavon, David and Chilton, Palma and Sanchez-Munoz, Cristobal and Cuenca, Magdalena and Arcella, Davide and Azzini, Elena and Barrison, Emma and Bevilacqua, Noemi and Buonocore, Pasquale and Catasta, Giovina and Censi, Laura and Ciarapica, Donatella and D'Acapito, Paola and Galfo, Myriam and Le Donne, Cinzia and Leclercq, Catherine and Maiani, Giuseppe and Mauro, Beatrice and Mistura, Lorenza and Pasquali, Antonella and Piccinelli, Raffaela and Polito, Angela and Roccaldo, Romana and Spada, Raffaella and Sette, Stefania and Zaccaria, Maria and Vitaglione, Paola and Montagnese, Concetta and De Bourdeaudhuij, Ilse and De Vriendt, Tineke and Matthys, Christophe and Vereecken, Carine and de Maeyer, Mieke and Ottevaere, Charlene and Phillipp, Katharina and Dietrich, Sabine and Boriss-Riedl, Birgit Kubelka Marion and Grammatikaki, Eva and Bouloubasi, Zoi and Cook, Tina Louisa and Eleutheriou, Sofia and Consta, Orsalia and Moschonis, George and Katsaroli, Ioanna and Kraniou, George and Papoutsou, Stab and Keke, Despoina and Petraki, Ioanna and Bellou, Elena and Tanagra, Sofia and Kallianoti, Kostalenia and Argyropoulou, Dionysia and Tsikrika, Stamatoula and Karaiskos, Christos and Meirhaeghe, Aline and Hagstromer, Maria and Wenntof, Anita Hurtig and Hallstrom, Lena and Patterson, Emma and Kwak, Lydia and Rizzo, Nico and Sanchez-Motero, Jackie and Pico, Elena and Navarro, Maite and Viadel, Blanca and Carreres, Jose Enrique and Merino, Gema and Sanjuan, Rosa and Lorente, Maria and Sanchez, Maria Jose and Thomas, Sarah and Allchurch, Elaine and Burgess, Peter and Astrom, Annika and Sverken, Anna and Broberg, Agneta and Masson, Annick and Lehoux, Claire and Brabant, Pascal and Pate, Philippe and Fontaine, Laurence and Sebok, Andras and Kuti, Tunde and Hegyi, Adrienn and Maldonado, Cristina and Llorente, Ana and Garcia, Emilio and von Fircks, Holger and Hallberg, Marianne Lilja and Messerer, Maria and Larsson, Mats and Fredriksson, Helena and Adamsson, Viola and Borjesson, Ingmar and Fernandez, Laura and Smillie, Laura and Wills, Josephine and Pedrero-Chamizo, Raquel and Melendez, Agustin and Valtuena, Jara and Albers, Ulrike and Benito, Pedro J and Gomez Lorente, Juan Jose and Canada, David and Urzanqui, Alejandro and Torres, Rosa Maria and Navarro, Paloma and HELENA, Study Group},
  issn         = {1436-6207},
  journal      = {EUROPEAN JOURNAL OF NUTRITION},
  keywords     = {POLYUNSATURATED FATTY-ACIDS,HEALTHY LIFE-STYLE,PHYSICAL-ACTIVITY,EUROPEAN ADOLESCENTS,MEDITERRANEAN DIET,LIVER-DISEASE,ALANINE,AMINOTRANSFERASE,BODY-FAT,INSULIN-RESISTANCE,INCREASED RISK,Sedentary behavior,Mediterranean diet,Low-grade inflammation,Moderation,Adolescents,HELENA study},
  language     = {eng},
  number       = {5},
  pages        = {2051--2065},
  title        = {Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study},
  url          = {http://dx.doi.org/10.1007/s00394-018-1764-4},
  volume       = {58},
  year         = {2019},
}

Altmetric
View in Altmetric
Web of Science
Times cited: