Advanced search

Diagnosis of peripheral bone and prosthetic joint infections: overview on the consensus documents by the EANM, EBJIS, and ESR (with ESCMID endorsement).

Author
Organization
Abstract
OBJECTIVES: Peripheral bone infection (PBI) and prosthetic joint infection (PJI) are two different infectious conditions of the musculoskeletal system. They have in common to be quite challenging to be diagnosed and no clear diagnostic flowchart has been established. Thus, a conjoined initiative on these two topics has been initiated by the European Society of Radiology (ESR), the European Association of Nuclear Medicine (EANM), the European Bone and Joint Infection Society (EBJIS), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). The purpose of this work is to provide an overview on the two consensus documents on PBI and PJI that originated by the conjoined work of the ESR, EANM, and EBJIS (with ESCMID endorsement). METHODS AND RESULTS: After literature search, a list of 18 statements for PBI and 25 statements for PJI were drafted in consensus on the most debated diagnostic challenges on these two topics, with emphasis on imaging. CONCLUSIONS: Overall, white blood cell scintigraphy and magnetic resonance imaging have individually demonstrated the highest diagnostic performance over other imaging modalities for the diagnosis of PBI and PJI. However, the choice of which advanced diagnostic modality to use first depends on several factors, such as the benefit for the patient, local experience of imaging specialists, costs, and availability. Since robust, comparative studies among most tests do not exist, the proposed flowcharts are based not only on existing literature but also on the opinion of multiple experts involved on these topics. KEY POINTS: • For peripheral bone infection and prosthetic joint infection, white blood cell and magnetic resonance imaging have individually demonstrated the highest diagnostic performance over other imaging modalities. • Two evidence- and expert-based diagnostic flowcharts involving variable combination of laboratory tests, biopsy methods, and radiological and nuclear medicine imaging modalities are proposed by a multi-society expert panel. • Clinical application of these flowcharts depends on several factors, such as the benefit for the patient, local experience, costs, and availability.
Keywords
Clinical laboratory techniques, Nuclear medicine, Osteomyelitis, Prosthesis-related infections, Radiology

Citation

Please use this url to cite or link to this publication:

Chicago
Sconfienza, Luca Maria, A. Signore, V. Cassar-Pullicino , M.A. Cataldo , O. Gheysens, O. Borens , A. Trampuz  , et al. 2019. “Diagnosis of Peripheral Bone and Prosthetic Joint Infections: Overview on the Consensus Documents by the EANM, EBJIS, and ESR (with ESCMID Endorsement).” European Radiology.
APA
Sconfienza, L. M., Signore, A., Cassar-Pullicino , V., Cataldo , M. A., Gheysens, O., Borens , O., Trampuz  , A., et al. (2019). Diagnosis of peripheral bone and prosthetic joint infections: overview on the consensus documents by the EANM, EBJIS, and ESR (with ESCMID endorsement). European Radiology.
Vancouver
1.
Sconfienza LM, Signore A, Cassar-Pullicino V, Cataldo MA, Gheysens O, Borens O, et al. Diagnosis of peripheral bone and prosthetic joint infections: overview on the consensus documents by the EANM, EBJIS, and ESR (with ESCMID endorsement). European Radiology. 2019;
MLA
Sconfienza, Luca Maria et al. “Diagnosis of Peripheral Bone and Prosthetic Joint Infections: Overview on the Consensus Documents by the EANM, EBJIS, and ESR (with ESCMID Endorsement).” European Radiology (2019): n. pag. Print.
@article{8623108,
  abstract     = {OBJECTIVES: 

Peripheral bone infection (PBI) and prosthetic joint infection (PJI) are two different infectious conditions of the musculoskeletal system. They have in common to be quite challenging to be diagnosed and no clear diagnostic flowchart has been established. Thus, a conjoined initiative on these two topics has been initiated by the European Society of Radiology (ESR), the European Association of Nuclear Medicine (EANM), the European Bone and Joint Infection Society (EBJIS), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). The purpose of this work is to provide an overview on the two consensus documents on PBI and PJI that originated by the conjoined work of the ESR, EANM, and EBJIS (with ESCMID endorsement).

METHODS AND RESULTS: 

After literature search, a list of 18 statements for PBI and 25 statements for PJI were drafted in consensus on the most debated diagnostic challenges on these two topics, with emphasis on imaging.

CONCLUSIONS: 

Overall, white blood cell scintigraphy and magnetic resonance imaging have individually demonstrated the highest diagnostic performance over other imaging modalities for the diagnosis of PBI and PJI. However, the choice of which advanced diagnostic modality to use first depends on several factors, such as the benefit for the patient, local experience of imaging specialists, costs, and availability. Since robust, comparative studies among most tests do not exist, the proposed flowcharts are based not only on existing literature but also on the opinion of multiple experts involved on these topics.

KEY POINTS: 

• For peripheral bone infection and prosthetic joint infection, white blood cell and magnetic resonance imaging have individually demonstrated the highest diagnostic performance over other imaging modalities. • Two evidence- and expert-based diagnostic flowcharts involving variable combination of laboratory tests, biopsy methods, and radiological and nuclear medicine imaging modalities are proposed by a multi-society expert panel. • Clinical application of these flowcharts depends on several factors, such as the benefit for the patient, local experience, costs, and availability.
},
  author       = {Sconfienza, Luca Maria and Signore, A. and Cassar-Pullicino , V. and  Cataldo , M.A. and Gheysens, O. and  Borens , O. and Trampuz  , A. and Wörtler , K. and Petrosillo  , N. and Winkler , H and Vanhoenacker, Filip and Jutte PC, P.C. and Glaudemans , A.W.J.M.},
  journal      = {European Radiology},
  keywords     = {Clinical laboratory techniques,Nuclear medicine,Osteomyelitis,Prosthesis-related infections,Radiology},
  language     = {eng},
  title        = {Diagnosis of peripheral bone and prosthetic joint infections: overview on the consensus documents by the EANM, EBJIS, and ESR (with ESCMID endorsement).},
  url          = {http://dx.doi.org/10.1007/s00330-019-06326-1},
  year         = {2019},
}

Altmetric
View in Altmetric