Advanced search
1 file | 407.56 KB Add to list

Quantitative and qualitative analysis of antimicrobial usage at farm and flock level on 181 broiler farms in nine European countries

Author
Organization
Abstract
Objectives To control the emerging threat of antimicrobial resistance, international policy appeals for appropriate monitoring of antimicrobial usage (AMU) at supranational, species and farm level. The aim of this study was to quantify AMU in broilers at farm and flock level in nine European countries. Methods Antimicrobial treatment data of one flock and purchased antimicrobials over one year were collected at 181 European broiler farms. Afterwards AMU was quantified using treatment incidence (TI) per 100days based on Defined Daily Dose (DDDvet), Defined Course Dose (DCDvet) or Used Daily Dose (UDDvet) values. Total AMU at flock level was obtained by summing the TIDDDvet of all treatments in the sampled flock (TIDDDvetFl*). Results The median TIDDDvetFl* was 9.0 (95% CI 5.5-10.8), meaning that broilers were treated with antimicrobials during 9% of their rearing period. TIDDDvetFl* varied considerably within and between countries. However, in every country at least one untreated flock was present. Average TIDDDvetFl* at country level ranged from 3.3 to 36.7. Polymyxins, extended-spectrum aminopenicillins and fluoroquinolones were the most used antimicrobials, accounting for 26%, 26% and 18% of total AMU, respectively. Twenty-six percent of the farms started a treatment on day 1 of production, and 49% of overall AMU was administered within the first week. Conclusions Results show that rearing broilers without AMU is feasible. However, a huge variation in AMU in terms of amount, moment of administration and antimicrobial classes was observed. This shows that there is still ground to be covered when it comes to AMU on broiler farms.
Keywords
Pharmacology (medical), Pharmacology, Infectious Diseases

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 407.56 KB

Citation

Please use this url to cite or link to this publication:

MLA
Joosten, Philip et al. “Quantitative and Qualitative Analysis of Antimicrobial Usage at Farm and Flock Level on 181 Broiler Farms in Nine European Countries.” JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 74.3 (2019): 798–806. Print.
APA
Joosten, P., Sarrazin, S., Van Gompel, L., Luiken, R. E. C., Mevius, D. J., Wagenaar, J. A., Heederik, D. J. J., et al. (2019). Quantitative and qualitative analysis of antimicrobial usage at farm and flock level on 181 broiler farms in nine European countries. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 74(3), 798–806.
Chicago author-date
Joosten, Philip, Steven Sarrazin, Liese Van Gompel, Roosmarijn E C Luiken, Dik J Mevius, Jaap A Wagenaar, Dick J J Heederik, et al. 2019. “Quantitative and Qualitative Analysis of Antimicrobial Usage at Farm and Flock Level on 181 Broiler Farms in Nine European Countries.” Journal of Antimicrobial Chemotherapy 74 (3): 798–806.
Chicago author-date (all authors)
Joosten, Philip, Steven Sarrazin, Liese Van Gompel, Roosmarijn E C Luiken, Dik J Mevius, Jaap A Wagenaar, Dick J J Heederik, Jeroen Dewulf, H Graveland, H Schmitt, D Mevius, A van Essen, B Gonzalez-Zorn, G Moyano, P Sanders, C Chauvin, J David, A Battisti, A Caprioli, T Blaha, K Wadepohl, M Brandt, F Aarestrup, T Hald, S Duarte, D Wasyl, D Krasucka, B Biernacki, J Szumilo, H Daskalov, H Saatkamp, and K Stärk. 2019. “Quantitative and Qualitative Analysis of Antimicrobial Usage at Farm and Flock Level on 181 Broiler Farms in Nine European Countries.” Journal of Antimicrobial Chemotherapy 74 (3): 798–806.
Vancouver
1.
Joosten P, Sarrazin S, Van Gompel L, Luiken REC, Mevius DJ, Wagenaar JA, et al. Quantitative and qualitative analysis of antimicrobial usage at farm and flock level on 181 broiler farms in nine European countries. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2019;74(3):798–806.
IEEE
[1]
P. Joosten et al., “Quantitative and qualitative analysis of antimicrobial usage at farm and flock level on 181 broiler farms in nine European countries,” JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, vol. 74, no. 3, pp. 798–806, 2019.
@article{8617311,
  abstract     = {Objectives To control the emerging threat of antimicrobial resistance, international policy appeals for appropriate monitoring of antimicrobial usage (AMU) at supranational, species and farm level. The aim of this study was to quantify AMU in broilers at farm and flock level in nine European countries.
Methods Antimicrobial treatment data of one flock and purchased antimicrobials over one year were collected at 181 European broiler farms. Afterwards AMU was quantified using treatment incidence (TI) per 100days based on Defined Daily Dose (DDDvet), Defined Course Dose (DCDvet) or Used Daily Dose (UDDvet) values. Total AMU at flock level was obtained by summing the TIDDDvet of all treatments in the sampled flock (TIDDDvetFl*).
Results The median TIDDDvetFl* was 9.0 (95% CI 5.5-10.8), meaning that broilers were treated with antimicrobials during 9% of their rearing period. TIDDDvetFl* varied considerably within and between countries. However, in every country at least one untreated flock was present. Average TIDDDvetFl* at country level ranged from 3.3 to 36.7. Polymyxins, extended-spectrum aminopenicillins and fluoroquinolones were the most used antimicrobials, accounting for 26%, 26% and 18% of total AMU, respectively. Twenty-six percent of the farms started a treatment on day 1 of production, and 49% of overall AMU was administered within the first week.
Conclusions Results show that rearing broilers without AMU is feasible. However, a huge variation in AMU in terms of amount, moment of administration and antimicrobial classes was observed. This shows that there is still ground to be covered when it comes to AMU on broiler farms.},
  author       = {Joosten, Philip and Sarrazin, Steven and Van Gompel, Liese and Luiken, Roosmarijn E C and Mevius, Dik J and Wagenaar, Jaap A and Heederik, Dick J J and Dewulf, Jeroen and Graveland, H and Schmitt, H and Mevius, D and van Essen, A and Gonzalez-Zorn, B and Moyano, G and Sanders, P and Chauvin, C and David, J and Battisti, A and Caprioli, A and Blaha, T and Wadepohl, K and Brandt, M and Aarestrup, F and Hald, T and Duarte, S and Wasyl, D and Krasucka, D and Biernacki, B and Szumilo, J and Daskalov, H and Saatkamp, H and Stärk, K},
  issn         = {0305-7453},
  journal      = {JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY},
  keywords     = {Pharmacology (medical),Pharmacology,Infectious Diseases},
  language     = {eng},
  number       = {3},
  pages        = {798--806},
  title        = {Quantitative and qualitative analysis of antimicrobial usage at farm and flock level on 181 broiler farms in nine European countries},
  url          = {http://dx.doi.org/10.1093/jac/dky498},
  volume       = {74},
  year         = {2019},
}

Altmetric
View in Altmetric
Web of Science
Times cited: