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Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project

(2018) EARLY HUMAN DEVELOPMENT. 120. p.53-60
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Abstract
Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. Aim: To analyze the associations of birth weight, length and ponderal index with height from infancy through adulthood within mono- and dizygotic twin pairs, which provides insights into the role of genetic and environmental individual-specific factors. Methods: This study is based on the data from 28 twin cohorts in 17 countries. The pooled data included 41,852 complete twin pairs (55% monozygotic and 45% same-sex dizygotic) with information on birth weight and a total of 112,409 paired height measurements at ages ranging from 1 to 69 years. Birth length was available for 19,881 complete twin pairs, with a total of 72,692 paired height measurements. The association between birth size and later height was analyzed at both the individual and within-pair level by linear regression analyses. Results: Within twin pairs, regression coefficients showed that a 1-kg increase in birth weight and a 1-cm increase in birth length were associated with 1.14-4.25 cm and 0.18-0.90 cm taller height, respectively. The magnitude of the associations was generally greater within dizygotic than within monozygotic twin pairs, and this difference between zygosities was more pronounced for birth length. Conclusion: Both genetic and individual-specific environmental factors play a role in the association between birth size and later height from infancy to adulthood, with a larger role for genetics in the association with birth length than with birth weight.
Keywords
FETAL ORIGINS HYPOTHESIS, CORONARY-HEART-DISEASE, FOR-GESTATIONAL-AGE, BODY-COMPOSITION, WEIGHT, LENGTH, TRACKING, STATURE, HEALTH, RISK, Birth weight, Birth length, Ponderal index, Height, Twins

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MLA
Jelenkovic, Aline et al. “Associations Between Birth Size and Later Height from Infancy Through Adulthood : an Individual Based Pooled Analysis of 28 Twin Cohorts Participating in the CODATwins Project.” EARLY HUMAN DEVELOPMENT 120 (2018): 53–60. Print.
APA
Jelenkovic, A., Yokoyama, Y., Sund, R., Hur, Y.-M., Harris, J. R., Brandt, I., Nilsen, T. S., et al. (2018). Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project. EARLY HUMAN DEVELOPMENT, 120, 53–60.
Chicago author-date
Jelenkovic, Aline, Yoshie Yokoyama, Reijo Sund, Yoon-Mi Hur, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, et al. 2018. “Associations Between Birth Size and Later Height from Infancy Through Adulthood : an Individual Based Pooled Analysis of 28 Twin Cohorts Participating in the CODATwins Project.” Early Human Development 120: 53–60.
Chicago author-date (all authors)
Jelenkovic, Aline, Yoshie Yokoyama, Reijo Sund, Yoon-Mi Hur, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Syuichi Ooki, Vilhelmina Ullemar, Catarina Almqvist, Patrik KE Magnusson, Kimberly J Saudino, Maria A Stazi, Corrado Fagnani, Sonia Brescianini, Tracy L Nelson, Keith E Whitfield, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Tessa L Cutler, John L Hopper, Clare H Llewellyn, Abigail Fisher, Robin P Corley, Brooke M Huibregtse, Catherine Derom, Robert F Vlietinck, Morten Bjerregaard-Andersen, Henning Beck Nielsen, Morten Sodemann, Robert F Krueger, Matt McGue, Shandell Pahlen, S Alexandra Burt, Kelly L Klump, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Gonneke Willemsen, Meike Bartels, Catharina EM van Beijsterveld, Jeffrey M Craig, Richard Saffery, Finn Rasmussen, Per Tynelius, Kauko Heikkila, Kirsi H Pietilainen, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Claire MA Haworth, Robert Plomin, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Adam D Tarnoki, David L Tarnoki, Jina Kim, Jooyeon Lee, Sooji Lee, Joohon Sung, Ruth JF Loos, Dorret I Boomsma, Thorkild IA Sorensen, Jaakko Kaprio, and Karri Silventoinen. 2018. “Associations Between Birth Size and Later Height from Infancy Through Adulthood : an Individual Based Pooled Analysis of 28 Twin Cohorts Participating in the CODATwins Project.” Early Human Development 120: 53–60.
Vancouver
1.
Jelenkovic A, Yokoyama Y, Sund R, Hur Y-M, Harris JR, Brandt I, et al. Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project. EARLY HUMAN DEVELOPMENT. 2018;120:53–60.
IEEE
[1]
A. Jelenkovic et al., “Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project,” EARLY HUMAN DEVELOPMENT, vol. 120, pp. 53–60, 2018.
@article{8615392,
  abstract     = {Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. 
Aim: To analyze the associations of birth weight, length and ponderal index with height from infancy through adulthood within mono- and dizygotic twin pairs, which provides insights into the role of genetic and environmental individual-specific factors. 
Methods: This study is based on the data from 28 twin cohorts in 17 countries. The pooled data included 41,852 complete twin pairs (55% monozygotic and 45% same-sex dizygotic) with information on birth weight and a total of 112,409 paired height measurements at ages ranging from 1 to 69 years. Birth length was available for 19,881 complete twin pairs, with a total of 72,692 paired height measurements. The association between birth size and later height was analyzed at both the individual and within-pair level by linear regression analyses. 
Results: Within twin pairs, regression coefficients showed that a 1-kg increase in birth weight and a 1-cm increase in birth length were associated with 1.14-4.25 cm and 0.18-0.90 cm taller height, respectively. The magnitude of the associations was generally greater within dizygotic than within monozygotic twin pairs, and this difference between zygosities was more pronounced for birth length. 
Conclusion: Both genetic and individual-specific environmental factors play a role in the association between birth size and later height from infancy to adulthood, with a larger role for genetics in the association with birth length than with birth weight.},
  author       = {Jelenkovic, Aline and Yokoyama, Yoshie and Sund, Reijo and Hur, Yoon-Mi and Harris, Jennifer R and Brandt, Ingunn and Nilsen, Thomas Sevenius and Ooki, Syuichi and Ullemar, Vilhelmina and Almqvist, Catarina and Magnusson, Patrik KE and Saudino, Kimberly J and Stazi, Maria A and Fagnani, Corrado and Brescianini, Sonia and Nelson, Tracy L and Whitfield, Keith E and Knafo-Noam, Ariel and Mankuta, David and Abramson, Lior and Cutler, Tessa L and Hopper, John L and Llewellyn, Clare H and Fisher, Abigail and Corley, Robin P and Huibregtse, Brooke M and Derom, Catherine and Vlietinck, Robert F and Bjerregaard-Andersen, Morten and Nielsen, Henning Beck and Sodemann, Morten and Krueger, Robert F and McGue, Matt and Pahlen, Shandell and Burt, S Alexandra and Klump, Kelly L and Dubois, Lise and Boivin, Michel and Brendgen, Mara and Dionne, Ginette and Vitaro, Frank and Willemsen, Gonneke and Bartels, Meike and van Beijsterveld, Catharina EM and Craig, Jeffrey M and Saffery, Richard and Rasmussen, Finn and Tynelius, Per and Heikkila, Kauko and Pietilainen, Kirsi H and Bayasgalan, Gombojav and Narandalai, Danshiitsoodol and Haworth, Claire MA and Plomin, Robert and Ji, Fuling and Ning, Feng and Pang, Zengchang and Rebato, Esther and Tarnoki, Adam D and Tarnoki, David L and Kim, Jina and Lee, Jooyeon and Lee, Sooji and Sung, Joohon and Loos, Ruth JF and Boomsma, Dorret I and Sorensen, Thorkild IA and Kaprio, Jaakko and Silventoinen, Karri},
  issn         = {0378-3782},
  journal      = {EARLY HUMAN DEVELOPMENT},
  keywords     = {FETAL ORIGINS HYPOTHESIS,CORONARY-HEART-DISEASE,FOR-GESTATIONAL-AGE,BODY-COMPOSITION,WEIGHT,LENGTH,TRACKING,STATURE,HEALTH,RISK,Birth weight,Birth length,Ponderal index,Height,Twins},
  language     = {eng},
  pages        = {53--60},
  title        = {Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project},
  url          = {http://dx.doi.org/10.1016/j.earlhumdev.2018.04.004},
  volume       = {120},
  year         = {2018},
}

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