Expanded preconception carrier screening in clinical practice : review of technology, guidelines, implementation challenges, and ethical quandaries
- Author
- Ting Zhang, Jody Madeira, Yao Lu, Yun Sun, Heidi Mertes (UGent) , Guido Pennings (UGent) and Steven R. Lindheim
- Organization
- Abstract
- In the last 10 years, expanded preconception carrier screening has become widely available and helps patients/couples make more informed decisions with regard to their reproductive options and facilitates more effective preconception planning, prenatal diagnosis, condition-specific counseling, and condition-specific care. This review provides an overview of expanded preconception carrier screening's high-throughput genotyping and sequencing approaches, current guidelines, implementation challenges and evolving ethical quandaries.
- Keywords
- Obstetrics and Gynaecology, expanded carrier screening, implementation, patient-physician, tOBSTETRICIAN-GYNECOLOGISTS, ATTITUDES, PERSPECTIVES, CARE, PARTICIPANTS, STATEMENT, OPINIONS, GENETICS, DISEASE, ASSAYesting decisions, third-party reproduction
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8611063
- MLA
- Zhang, Ting, et al. “Expanded Preconception Carrier Screening in Clinical Practice : Review of Technology, Guidelines, Implementation Challenges, and Ethical Quandaries.” CLINICAL OBSTETRICS AND GYNECOLOGY, vol. 62, no. 2, 2019, pp. 217–27, doi:10.1097/grf.0000000000000437.
- APA
- Zhang, T., Madeira, J., Lu, Y., Sun, Y., Mertes, H., Pennings, G., & Lindheim, S. R. (2019). Expanded preconception carrier screening in clinical practice : review of technology, guidelines, implementation challenges, and ethical quandaries. CLINICAL OBSTETRICS AND GYNECOLOGY, 62(2), 217–227. https://doi.org/10.1097/grf.0000000000000437
- Chicago author-date
- Zhang, Ting, Jody Madeira, Yao Lu, Yun Sun, Heidi Mertes, Guido Pennings, and Steven R. Lindheim. 2019. “Expanded Preconception Carrier Screening in Clinical Practice : Review of Technology, Guidelines, Implementation Challenges, and Ethical Quandaries.” CLINICAL OBSTETRICS AND GYNECOLOGY 62 (2): 217–27. https://doi.org/10.1097/grf.0000000000000437.
- Chicago author-date (all authors)
- Zhang, Ting, Jody Madeira, Yao Lu, Yun Sun, Heidi Mertes, Guido Pennings, and Steven R. Lindheim. 2019. “Expanded Preconception Carrier Screening in Clinical Practice : Review of Technology, Guidelines, Implementation Challenges, and Ethical Quandaries.” CLINICAL OBSTETRICS AND GYNECOLOGY 62 (2): 217–227. doi:10.1097/grf.0000000000000437.
- Vancouver
- 1.Zhang T, Madeira J, Lu Y, Sun Y, Mertes H, Pennings G, et al. Expanded preconception carrier screening in clinical practice : review of technology, guidelines, implementation challenges, and ethical quandaries. CLINICAL OBSTETRICS AND GYNECOLOGY. 2019;62(2):217–27.
- IEEE
- [1]T. Zhang et al., “Expanded preconception carrier screening in clinical practice : review of technology, guidelines, implementation challenges, and ethical quandaries,” CLINICAL OBSTETRICS AND GYNECOLOGY, vol. 62, no. 2, pp. 217–227, 2019.
@article{8611063,
abstract = {{In the last 10 years, expanded preconception carrier screening has become widely available and helps patients/couples make more informed decisions with regard to their reproductive options and facilitates more effective preconception planning, prenatal diagnosis, condition-specific counseling, and condition-specific care. This review provides an overview of expanded preconception carrier screening's high-throughput genotyping and sequencing approaches, current guidelines, implementation challenges and evolving ethical quandaries.}},
author = {{Zhang, Ting and Madeira, Jody and Lu, Yao and Sun, Yun and Mertes, Heidi and Pennings, Guido and Lindheim, Steven R.}},
issn = {{0009-9201}},
journal = {{CLINICAL OBSTETRICS AND GYNECOLOGY}},
keywords = {{Obstetrics and Gynaecology,expanded carrier screening,implementation,patient-physician,tOBSTETRICIAN-GYNECOLOGISTS,ATTITUDES,PERSPECTIVES,CARE,PARTICIPANTS,STATEMENT,OPINIONS,GENETICS,DISEASE,ASSAYesting decisions,third-party reproduction}},
language = {{eng}},
number = {{2}},
pages = {{217--227}},
title = {{Expanded preconception carrier screening in clinical practice : review of technology, guidelines, implementation challenges, and ethical quandaries}},
url = {{http://doi.org/10.1097/grf.0000000000000437}},
volume = {{62}},
year = {{2019}},
}
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