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Clinical and electrophysiological markers of Primary Progressive Aphasia: a systematic review

(2019)
Author
Organization
Abstract
Primary Progressive Aphasia (PPA) refers to a group of clinical syndromes characterized by the progressive loss of language functions with initial preservation of the other cognitive functions. Despite the availability of international guidelines for diagnosing PPA and its variants (Gorno-Tempini et al., 2011), the differential diagnosis and clinical distinction between variants in the early disease stage remains complex and challenging. Consequently, the aim of this systematic review was to establish language, speech and electrophysiological markers to identify PPA and its variants. To provide clinical markers, studies in which the initial symptoms were reported by the patients or their family and studies in which the quantitative and qualitative results of the speech and language assessments performed at initial specialty referral were described, were included. Furthermore, studies in which an electrophysiological measurement technique was used in patients with PPA were included in the systematic review. An overview of the initial symptoms, the initial speech and language assessments and electrophysiological techniques to improve an early-stage diagnosis of PPA is provided in this poster. However, research on the electrophysiological processes in PPA is still limited, only seven electrophysiological studies were included in this review. Further research is required to investigate the applicability of electrophysiological measurement techniques for diagnosing PPA.
Keywords
Primary Progressive Aphasia, diagnosis, early-stage, electrophysiology

Citation

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Chicago
Stalpaert, Jara, Elissa-Marie Cocquyt, Lieselot Segers, Tim Van Langenhove, Marijke Miatton, Pieter van Mierlo, and Miet De Letter. 2019. “Clinical and Electrophysiological Markers of Primary Progressive Aphasia: a Systematic Review.” In .
APA
Stalpaert, J., Cocquyt, E.-M., Segers, L., Van Langenhove, T., Miatton, M., van Mierlo, P., & De Letter, M. (2019). Clinical and electrophysiological markers of Primary Progressive Aphasia: a systematic review. Presented at the Research Day & Student Research Symposium.
Vancouver
1.
Stalpaert J, Cocquyt E-M, Segers L, Van Langenhove T, Miatton M, van Mierlo P, et al. Clinical and electrophysiological markers of Primary Progressive Aphasia: a systematic review. 2019.
MLA
Stalpaert, Jara et al. “Clinical and Electrophysiological Markers of Primary Progressive Aphasia: a Systematic Review.” 2019. Print.
@inproceedings{8610811,
  abstract     = {Primary Progressive Aphasia (PPA) refers to a group of clinical syndromes characterized by the progressive loss of language functions with initial preservation of the other cognitive functions. Despite the availability of international guidelines for diagnosing PPA and its variants (Gorno-Tempini et al., 2011), the differential diagnosis and clinical distinction between variants in the early disease stage remains complex and challenging. Consequently, the aim of this systematic review was to establish language, speech and electrophysiological markers to identify PPA and its variants. To provide clinical markers, studies in which the initial symptoms were reported by the patients or their family and studies in which the quantitative and qualitative results of the speech and language assessments performed at initial specialty referral were described, were included. Furthermore, studies in which an electrophysiological measurement technique was used in patients with PPA were included in the systematic review. An overview of the initial symptoms, the initial speech and language assessments and electrophysiological techniques to improve an early-stage diagnosis of PPA is provided in this poster. However, research on the electrophysiological processes in PPA is still limited, only seven electrophysiological studies were included in this review. Further research is required to investigate the applicability of electrophysiological measurement techniques for diagnosing PPA. },
  author       = {Stalpaert, Jara and Cocquyt, Elissa-Marie and Segers, Lieselot and Van Langenhove, Tim and Miatton, Marijke and van Mierlo, Pieter and De Letter, Miet},
  location     = {Ghent},
  title        = {Clinical and electrophysiological markers of Primary Progressive Aphasia: a systematic review},
  year         = {2019},
}