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Variation of meningioma in response to cyproterone acetate in a trans woman

Mirra Boer (UGent) , Loes Moernaut (UGent) , Frank Van Calenbergh, Bruno Lapauw (UGent) and Guy T'Sjoen (UGent)
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Organization
Abstract
Background: Meningiomas express estrogen and progesterone receptors, suggestive of hormonal responsiveness. So far, eight cases of trans women with a meningioma have been reported in the literature. Methods: Detailed report of the symptoms, treatment, and follow-up of an individual transgender patient with a meningioma. Results: A trans woman treated long-term with gender affirming hormone therapy, including cyproterone acetate, a synthetic progestin and anti-androgen, was diagnosed with a meningioma, significantly expanding in volume over 10 years. After stopping cyproterone acetate a substantial volume decrease of the meningioma was noticed within 3 months. Conclusion: This addition to the literature demonstrates that a conservative approach with interruption of cyproterone acetate may be a sufficient intervention, obviating the need for additional neurosurgical treatment.
Keywords
Trans woman, meningioma, estrogen, progesterone, cyproterone acetate, SEX HORMONE-TREATMENT, TRANSSEXUAL PATIENT, ESTROGEN, THERAPY, RISK

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Please use this url to cite or link to this publication:

MLA
Boer, Mirra et al. “Variation of Meningioma in Response to Cyproterone Acetate in a Trans Woman.” INTERNATIONAL JOURNAL OF TRANSGENDERISM 19.1 (2018): 92–94. Print.
APA
Boer, M., Moernaut, L., Van Calenbergh, F., Lapauw, B., & T’Sjoen, G. (2018). Variation of meningioma in response to cyproterone acetate in a trans woman. INTERNATIONAL JOURNAL OF TRANSGENDERISM, 19(1), 92–94.
Chicago author-date
Boer, Mirra, Loes Moernaut, Frank Van Calenbergh, Bruno Lapauw, and Guy T’Sjoen. 2018. “Variation of Meningioma in Response to Cyproterone Acetate in a Trans Woman.” International Journal of Transgenderism 19 (1): 92–94.
Chicago author-date (all authors)
Boer, Mirra, Loes Moernaut, Frank Van Calenbergh, Bruno Lapauw, and Guy T’Sjoen. 2018. “Variation of Meningioma in Response to Cyproterone Acetate in a Trans Woman.” International Journal of Transgenderism 19 (1): 92–94.
Vancouver
1.
Boer M, Moernaut L, Van Calenbergh F, Lapauw B, T’Sjoen G. Variation of meningioma in response to cyproterone acetate in a trans woman. INTERNATIONAL JOURNAL OF TRANSGENDERISM. 2018;19(1):92–4.
IEEE
[1]
M. Boer, L. Moernaut, F. Van Calenbergh, B. Lapauw, and G. T’Sjoen, “Variation of meningioma in response to cyproterone acetate in a trans woman,” INTERNATIONAL JOURNAL OF TRANSGENDERISM, vol. 19, no. 1, pp. 92–94, 2018.
@article{8607610,
  abstract     = {Background: Meningiomas express estrogen and progesterone receptors, suggestive of hormonal responsiveness. So far, eight cases of trans women with a meningioma have been reported in the literature. 
Methods: Detailed report of the symptoms, treatment, and follow-up of an individual transgender patient with a meningioma. 
Results: A trans woman treated long-term with gender affirming hormone therapy, including cyproterone acetate, a synthetic progestin and anti-androgen, was diagnosed with a meningioma, significantly expanding in volume over 10 years. After stopping cyproterone acetate a substantial volume decrease of the meningioma was noticed within 3 months. 
Conclusion: This addition to the literature demonstrates that a conservative approach with interruption of cyproterone acetate may be a sufficient intervention, obviating the need for additional neurosurgical treatment.},
  author       = {Boer, Mirra and Moernaut, Loes and Van Calenbergh, Frank and Lapauw, Bruno and T'Sjoen, Guy},
  issn         = {1553-2739},
  journal      = {INTERNATIONAL JOURNAL OF TRANSGENDERISM},
  keywords     = {Trans woman,meningioma,estrogen,progesterone,cyproterone acetate,SEX HORMONE-TREATMENT,TRANSSEXUAL PATIENT,ESTROGEN,THERAPY,RISK},
  language     = {eng},
  number       = {1},
  pages        = {92--94},
  title        = {Variation of meningioma in response to cyproterone acetate in a trans woman},
  url          = {http://dx.doi.org/10.1080/15532739.2017.1413615},
  volume       = {19},
  year         = {2018},
}

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