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Clinical aspects of egg bioactive peptide research : a review

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Abstract
Extensive in vitro and, to a more limited extent, animal research have demonstrated the health potential of a wide set of egg protein hydrolysates; however, well-designed human intervention studies are scarce. Health claim assessment, however, sets high standards for characterisation of the bioactive peptides, investigation of the mode-of-action and convincing human intervention studies. In this review, we discuss the state-of-the-art and knowledge gaps related to egg-derived peptide bioavailability and bioactivity. In addition, we will formulate recommendations for appropriate design of future human intervention trials with egg-derived peptides.
Keywords
Angiotensin-converting enzyme, bioavailability, clinical study, egg-derived peptides, inflammation, NORMAL BLOOD-PRESSURE, LONG-TERM INTAKE, ENZYME-INHIBITORY-ACTIVITY, GASTROINTESTINAL DIGESTION, WHITE HYDROLYSATE, TRANSEPITHELIAL TRANSPORT, ANTIHYPERTENSIVE PEPTIDE, PROTEIN HYDROLYSATE, CASEIN HYDROLYSATE, PROLINE-PROLINE

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Citation

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MLA
Grootaert, Charlotte et al. “Clinical Aspects of Egg Bioactive Peptide Research : a Review.” INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY 54.6 (2019): 1967–1975. Print.
APA
Grootaert, C., Voorspoels, S., Jacobs, G., Matthijs, B., Possemiers, S., Van der Saag, H., Van Camp, J., et al. (2019). Clinical aspects of egg bioactive peptide research : a review. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54(6), 1967–1975.
Chicago author-date
Grootaert, Charlotte, Stefan Voorspoels, Griet Jacobs, Bea Matthijs, Sam Possemiers, Hans Van der Saag, John Van Camp, and Alice Lucey. 2019. “Clinical Aspects of Egg Bioactive Peptide Research : a Review.” International Journal of Food Science and Technology 54 (6): 1967–1975.
Chicago author-date (all authors)
Grootaert, Charlotte, Stefan Voorspoels, Griet Jacobs, Bea Matthijs, Sam Possemiers, Hans Van der Saag, John Van Camp, and Alice Lucey. 2019. “Clinical Aspects of Egg Bioactive Peptide Research : a Review.” International Journal of Food Science and Technology 54 (6): 1967–1975.
Vancouver
1.
Grootaert C, Voorspoels S, Jacobs G, Matthijs B, Possemiers S, Van der Saag H, et al. Clinical aspects of egg bioactive peptide research : a review. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY. 2019;54(6):1967–75.
IEEE
[1]
C. Grootaert et al., “Clinical aspects of egg bioactive peptide research : a review,” INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, vol. 54, no. 6, pp. 1967–1975, 2019.
@article{8605630,
  abstract     = {Extensive in vitro and, to a more limited extent, animal research have demonstrated the health potential of a wide set of egg protein hydrolysates; however, well-designed human intervention studies are scarce. Health claim assessment, however, sets high standards for characterisation of the bioactive peptides, investigation of the mode-of-action and convincing human intervention studies. In this review, we discuss the state-of-the-art and knowledge gaps related to egg-derived peptide bioavailability and bioactivity. In addition, we will formulate recommendations for appropriate design of future human intervention trials with egg-derived peptides.},
  author       = {Grootaert, Charlotte and Voorspoels, Stefan and Jacobs, Griet and Matthijs, Bea and Possemiers, Sam and Van der Saag, Hans and Van Camp, John and Lucey, Alice},
  issn         = {0950-5423},
  journal      = {INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY},
  keywords     = {Angiotensin-converting enzyme,bioavailability,clinical study,egg-derived peptides,inflammation,NORMAL BLOOD-PRESSURE,LONG-TERM INTAKE,ENZYME-INHIBITORY-ACTIVITY,GASTROINTESTINAL DIGESTION,WHITE HYDROLYSATE,TRANSEPITHELIAL TRANSPORT,ANTIHYPERTENSIVE PEPTIDE,PROTEIN HYDROLYSATE,CASEIN HYDROLYSATE,PROLINE-PROLINE},
  language     = {eng},
  number       = {6},
  pages        = {1967--1975},
  title        = {Clinical aspects of egg bioactive peptide research : a review},
  url          = {http://dx.doi.org/10.1111/ijfs.14139},
  volume       = {54},
  year         = {2019},
}

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