Advanced search
1 file | 497.63 KB Add to list

Does the Mediterranean diet protect against stress-induced inflammatory activation in European adolescents? : the HELENA study

(2018) NUTRIENTS. 10(11).
Author
Organization
Abstract
Stress increases inflammation but whether adherence to Mediterranean diet counteracts this association and how early can these effects be observed is not well known. We tested whether (1) cortisol is associated to inflammation, (2) cortisol is associated to the adolescent Mediterranean diet score (aMDS), (3) aMDS lessens inflammation, (4) aMDS associates with cortisol levels and inflammation. Two hundred and forty-two adolescents (137 females; 12.5-17.5 years old) provided salivary cortisol, blood and 2-day 24-h dietary recall from which aMDS was derived. Cortisol levels were associated with increased tumor necrosis factor (TNF-alpha B = 11.887, p = 0.001) when adjusted for age, gender, parental education and body mass index (BMI). Moreover, cortisol levels were inversely associated to adherence to the Mediterranean Diet (B = -1.023, p = 0.002). Adolescents with higher adherence to aMDS had lower levels of interleukins (IL) IL-1, IL-2, IL-6 and TNF-alpha, compared to those who did not adhere. The association between cortisol and TNF-alpha was no longer significant when aMDS was included in the model (B = 6.118, p = 0.139). In addition, comparing lower and higher aMDS groups, the association between cortisol and TNF-alpha was only observed in those with lower aMDS adherence. Our study suggests that adherence to the Mediterranean Diet may counteract the effect of stress on inflammatory biomarkers which may contribute to decreasing the risk of future mental health.
Keywords
diet quality, depressive symptoms, risk factors, epidemiology, immune system, prevention, hypothalamic-pituitary-adrenal-HPA axis, HEALTHY LIFE-STYLE, C-REACTIVE PROTEIN, DEPRESSIVE SYMPTOMS, NUTRITIONAL-STATUS, PHYSICAL-ACTIVITY, PUBERTAL CHANGES, QUALITY, CHILDREN, PATTERN, RISK

Downloads

  • nutrients carvalho stress-diet-inflammation.pdf
    • full text
    • |
    • open access
    • |
    • PDF
    • |
    • 497.63 KB

Citation

Please use this url to cite or link to this publication:

MLA
Carvalho, Kenia et al. “Does the Mediterranean Diet Protect Against Stress-induced Inflammatory Activation in European Adolescents? : the HELENA Study.” NUTRIENTS 10.11 (2018): n. pag. Print.
APA
Carvalho, K., Ronca, D., Michels, N., Huybrechts, I., Cuenca-Garcia, M., Marcos, A., Molnár, D., et al. (2018). Does the Mediterranean diet protect against stress-induced inflammatory activation in European adolescents? : the HELENA study. NUTRIENTS, 10(11).
Chicago author-date
Carvalho, Kenia, Débora Ronca, Nathalie Michels, Inge Huybrechts, Magdalena Cuenca-Garcia, Ascensión Marcos, Dénes Molnár, et al. 2018. “Does the Mediterranean Diet Protect Against Stress-induced Inflammatory Activation in European Adolescents? : the HELENA Study.” Nutrients 10 (11).
Chicago author-date (all authors)
Carvalho, Kenia, Débora Ronca, Nathalie Michels, Inge Huybrechts, Magdalena Cuenca-Garcia, Ascensión Marcos, Dénes Molnár, Jean Dallongeville, Yannis Manios, Beatriz Schaan, Luis Moreno, Stefaan De Henauw, and Livia Carvalho. 2018. “Does the Mediterranean Diet Protect Against Stress-induced Inflammatory Activation in European Adolescents? : the HELENA Study.” Nutrients 10 (11).
Vancouver
1.
Carvalho K, Ronca D, Michels N, Huybrechts I, Cuenca-Garcia M, Marcos A, et al. Does the Mediterranean diet protect against stress-induced inflammatory activation in European adolescents? : the HELENA study. NUTRIENTS. 2018;10(11).
IEEE
[1]
K. Carvalho et al., “Does the Mediterranean diet protect against stress-induced inflammatory activation in European adolescents? : the HELENA study,” NUTRIENTS, vol. 10, no. 11, 2018.
@article{8602891,
  abstract     = {Stress increases inflammation but whether adherence to Mediterranean diet counteracts this association and how early can these effects be observed is not well known. We tested whether (1) cortisol is associated to inflammation, (2) cortisol is associated to the adolescent Mediterranean diet score (aMDS), (3) aMDS lessens inflammation, (4) aMDS associates with cortisol levels and inflammation. Two hundred and forty-two adolescents (137 females; 12.5-17.5 years old) provided salivary cortisol, blood and 2-day 24-h dietary recall from which aMDS was derived. Cortisol levels were associated with increased tumor necrosis factor (TNF-alpha B = 11.887, p = 0.001) when adjusted for age, gender, parental education and body mass index (BMI). Moreover, cortisol levels were inversely associated to adherence to the Mediterranean Diet (B = -1.023, p = 0.002). Adolescents with higher adherence to aMDS had lower levels of interleukins (IL) IL-1, IL-2, IL-6 and TNF-alpha, compared to those who did not adhere. The association between cortisol and TNF-alpha was no longer significant when aMDS was included in the model (B = 6.118, p = 0.139). In addition, comparing lower and higher aMDS groups, the association between cortisol and TNF-alpha was only observed in those with lower aMDS adherence. Our study suggests that adherence to the Mediterranean Diet may counteract the effect of stress on inflammatory biomarkers which may contribute to decreasing the risk of future mental health.},
  articleno    = {1770},
  author       = {Carvalho, Kenia and Ronca, Débora and Michels, Nathalie and Huybrechts, Inge and Cuenca-Garcia, Magdalena and Marcos, Ascensión and Molnár, Dénes and Dallongeville, Jean and Manios, Yannis and Schaan, Beatriz and Moreno, Luis and De Henauw, Stefaan and Carvalho, Livia},
  issn         = {2072-6643},
  journal      = {NUTRIENTS},
  keywords     = {diet quality,depressive symptoms,risk factors,epidemiology,immune system,prevention,hypothalamic-pituitary-adrenal-HPA axis,HEALTHY LIFE-STYLE,C-REACTIVE PROTEIN,DEPRESSIVE SYMPTOMS,NUTRITIONAL-STATUS,PHYSICAL-ACTIVITY,PUBERTAL CHANGES,QUALITY,CHILDREN,PATTERN,RISK},
  language     = {eng},
  number       = {11},
  pages        = {9},
  title        = {Does the Mediterranean diet protect against stress-induced inflammatory activation in European adolescents? : the HELENA study},
  url          = {http://dx.doi.org/10.3390/nu10111770},
  volume       = {10},
  year         = {2018},
}

Altmetric
View in Altmetric
Web of Science
Times cited: