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The Diels-Alder reaction : doomed to academic praise only?

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Abstract
The Diels-Alder reaction is universally acknowledged for its atom-efficient and simple access to molecular complexity. This textbook example of a green reaction forms one of the most efficient routes towards six-membered rings. However, a large gap is noticed between the relevance and versatility in the academic world, implying a small scale, and industrial use. Obviously, the current developed Diels-Alder procedures are failing to make their way into industry. This perspective paper will gave a critical overview of the most important bottlenecks of Diels-Alder reactions. Flow chemistry, a key research area for green engineering, is a powerful tool to facilitate a safe transfer of Diels Alder processes to the industrial environment.
Keywords
Diels-Alder, green chemistry, scale-up, flow, microreactor

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Citation

Please use this url to cite or link to this publication:

MLA
Seghers, Sofie, et al. “The Diels-Alder Reaction : Doomed to Academic Praise Only?” CHIMICA OGGI-CHEMISTRY TODAY, vol. 36, no. 2, 2018, pp. 40–43.
APA
Seghers, S., Thybaut, J., & Stevens, C. (2018). The Diels-Alder reaction : doomed to academic praise only? CHIMICA OGGI-CHEMISTRY TODAY, 36(2), 40–43.
Chicago author-date
Seghers, Sofie, Joris Thybaut, and Christian Stevens. 2018. “The Diels-Alder Reaction : Doomed to Academic Praise Only?” CHIMICA OGGI-CHEMISTRY TODAY 36 (2): 40–43.
Chicago author-date (all authors)
Seghers, Sofie, Joris Thybaut, and Christian Stevens. 2018. “The Diels-Alder Reaction : Doomed to Academic Praise Only?” CHIMICA OGGI-CHEMISTRY TODAY 36 (2): 40–43.
Vancouver
1.
Seghers S, Thybaut J, Stevens C. The Diels-Alder reaction : doomed to academic praise only? CHIMICA OGGI-CHEMISTRY TODAY. 2018;36(2):40–3.
IEEE
[1]
S. Seghers, J. Thybaut, and C. Stevens, “The Diels-Alder reaction : doomed to academic praise only?,” CHIMICA OGGI-CHEMISTRY TODAY, vol. 36, no. 2, pp. 40–43, 2018.
@article{8601247,
  abstract     = {{The Diels-Alder reaction is universally acknowledged for its atom-efficient and simple access to molecular complexity. This textbook example of a green reaction forms one of the most efficient routes towards six-membered rings. However, a large gap is noticed between the relevance and versatility in the academic world, implying a small scale, and industrial use. Obviously, the current developed Diels-Alder procedures are failing to make their way into industry. This perspective paper will gave a critical overview of the most important bottlenecks of Diels-Alder reactions. Flow chemistry, a key research area for green engineering, is a powerful tool to facilitate a safe transfer of Diels Alder processes to the industrial environment.}},
  author       = {{Seghers, Sofie and Thybaut, Joris and Stevens, Christian}},
  issn         = {{0392-839X}},
  journal      = {{CHIMICA OGGI-CHEMISTRY TODAY}},
  keywords     = {{Diels-Alder,green chemistry,scale-up,flow,microreactor}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{40--43}},
  title        = {{The Diels-Alder reaction : doomed to academic praise only?}},
  volume       = {{36}},
  year         = {{2018}},
}

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