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Ewing's sarcoma and primary osseous lymphoma : spectrum of imaging appearances

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Abstract
Ewing's sarcoma (ES) is a rare, highly malignant anaplastic stem cell tumor. Histologically, the tumor consists of uniform densely packed small monomorphic cells with round nuclei. The typical appearance at hematoxylin and eosin (H&E) staining is small blue round cells without any matrix formation. On conventional radiography, ES typically presents as a permeative lesion in the diaphysis of a long bone in a child. A large soft tissue component is another characteristic feature, best depicted by magnetic resonance imaging. Primary osseous lymphomas are most commonly highly malignant B-cell lymphomas. At H&E histologic staining, the tumor stroma consists of diffuse round-cell infiltrates that resembles the appearance of ES. Although there is no typical imaging appearance of an osseous lymphoma, it should be considered in an adult presenting with a Lodwick grade II or III lesion in the metaphysis or diaphysis of a large long bone, the pelvis, or the vertebral column. Histologic confirmation is mandatory.
Keywords
Ewing's Sarcoma, primary osseous lymphoma, radiography, magnetic resonance imaging, review, BONE-MARROW INVOLVEMENT, NON-HODGKINS-LYMPHOMA, WHOLE-BODY MRI, MALIGNANT-LYMPHOMA, TUMORS, LESIONS, FAMILY, GROWTH

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MLA
Weber, Marc-André, et al. “Ewing’s Sarcoma and Primary Osseous Lymphoma : Spectrum of Imaging Appearances.” SEMINARS IN MUSCULOSKELETAL RADIOLOGY, vol. 23, no. 1, 2019, pp. 36–57, doi:10.1055/s-0038-1676125.
APA
Weber, M.-A., Papakonstantinou, O., Nikodinovska, V. V., & Vanhoenacker, F. (2019). Ewing’s sarcoma and primary osseous lymphoma : spectrum of imaging appearances. SEMINARS IN MUSCULOSKELETAL RADIOLOGY, 23(1), 36–57. https://doi.org/10.1055/s-0038-1676125
Chicago author-date
Weber, Marc-André, Olympia Papakonstantinou, Violeta Vasilevska Nikodinovska, and Filip Vanhoenacker. 2019. “Ewing’s Sarcoma and Primary Osseous Lymphoma : Spectrum of Imaging Appearances.” SEMINARS IN MUSCULOSKELETAL RADIOLOGY 23 (1): 36–57. https://doi.org/10.1055/s-0038-1676125.
Chicago author-date (all authors)
Weber, Marc-André, Olympia Papakonstantinou, Violeta Vasilevska Nikodinovska, and Filip Vanhoenacker. 2019. “Ewing’s Sarcoma and Primary Osseous Lymphoma : Spectrum of Imaging Appearances.” SEMINARS IN MUSCULOSKELETAL RADIOLOGY 23 (1): 36–57. doi:10.1055/s-0038-1676125.
Vancouver
1.
Weber M-A, Papakonstantinou O, Nikodinovska VV, Vanhoenacker F. Ewing’s sarcoma and primary osseous lymphoma : spectrum of imaging appearances. SEMINARS IN MUSCULOSKELETAL RADIOLOGY. 2019;23(1):36–57.
IEEE
[1]
M.-A. Weber, O. Papakonstantinou, V. V. Nikodinovska, and F. Vanhoenacker, “Ewing’s sarcoma and primary osseous lymphoma : spectrum of imaging appearances,” SEMINARS IN MUSCULOSKELETAL RADIOLOGY, vol. 23, no. 1, pp. 36–57, 2019.
@article{8600031,
  abstract     = {{Ewing's sarcoma (ES) is a rare, highly malignant anaplastic stem cell tumor. Histologically, the tumor consists of uniform densely packed small monomorphic cells with round nuclei. The typical appearance at hematoxylin and eosin (H&E) staining is small blue round cells without any matrix formation. On conventional radiography, ES typically presents as a permeative lesion in the diaphysis of a long bone in a child. A large soft tissue component is another characteristic feature, best depicted by magnetic resonance imaging. Primary osseous lymphomas are most commonly highly malignant B-cell lymphomas. At H&E histologic staining, the tumor stroma consists of diffuse round-cell infiltrates that resembles the appearance of ES. Although there is no typical imaging appearance of an osseous lymphoma, it should be considered in an adult presenting with a Lodwick grade II or III lesion in the metaphysis or diaphysis of a large long bone, the pelvis, or the vertebral column. Histologic confirmation is mandatory.}},
  author       = {{Weber, Marc-André and Papakonstantinou, Olympia and Nikodinovska, Violeta Vasilevska and Vanhoenacker, Filip}},
  issn         = {{1089-7860}},
  journal      = {{SEMINARS IN MUSCULOSKELETAL RADIOLOGY}},
  keywords     = {{Ewing's Sarcoma,primary osseous lymphoma,radiography,magnetic resonance imaging,review,BONE-MARROW INVOLVEMENT,NON-HODGKINS-LYMPHOMA,WHOLE-BODY MRI,MALIGNANT-LYMPHOMA,TUMORS,LESIONS,FAMILY,GROWTH}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{36--57}},
  title        = {{Ewing's sarcoma and primary osseous lymphoma : spectrum of imaging appearances}},
  url          = {{http://doi.org/10.1055/s-0038-1676125}},
  volume       = {{23}},
  year         = {{2019}},
}

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