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Impact of the microenvironment on tumour budding in colorectal cancer

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Abstract
Tumour Budding (TB) is recognized as an adverse prognostic factor in colorectal cancer (CRC). TB is the detachment of isolated cancer cells or small clusters of such cells mainly at the invasion front. One question that arises is of the role of the tumour stroma regarding the permissiveness of the formation and progression of TB. In this review, we will examine potential factors affecting TB, in particular we will analyse the potential effect of inflammation, hypoxia, extracellular matrix and Cancer-Associated Fibroblasts (CAFs).
Keywords
Budding, Cancer-associated fibroblast, Epithelial-mesenchymal transition, Migration, Tumor-environment, CARCINOMA-ASSOCIATED FIBROBLASTS, MISMATCH REPAIR-PROFICIENT, LYMPH-NODE METASTASIS, EXPRESSION, MYOFIBROBLASTS, PROGRESSION, INVASION, STROMA, CELLS, COLON

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Citation

Please use this url to cite or link to this publication:

MLA
Georges, Laurent MC et al. “Impact of the Microenvironment on Tumour Budding in Colorectal Cancer.” Ed. P Jordan. Advances in Experimental Medicine and Biology 1110 (2018): 101–111. Print.
APA
Georges, L. M., Verset, L., Zlobec, I., Demetter, P., & De Wever, O. (2018). Impact of the microenvironment on tumour budding in colorectal cancer. (P. Jordan, Ed.)Advances in Experimental Medicine and Biology, 1110, 101–111.
Chicago author-date
Georges, Laurent MC, Laurine Verset, Inti Zlobec, Pieter Demetter, and Olivier De Wever. 2018. “Impact of the Microenvironment on Tumour Budding in Colorectal Cancer.” Ed. P Jordan. Advances in Experimental Medicine and Biology 1110: 101–111.
Chicago author-date (all authors)
Georges, Laurent MC, Laurine Verset, Inti Zlobec, Pieter Demetter, and Olivier De Wever. 2018. “Impact of the Microenvironment on Tumour Budding in Colorectal Cancer.” Ed. P Jordan. Advances in Experimental Medicine and Biology 1110: 101–111.
Vancouver
1.
Georges LM, Verset L, Zlobec I, Demetter P, De Wever O. Impact of the microenvironment on tumour budding in colorectal cancer. Jordan P, editor. Advances in Experimental Medicine and Biology. Cham, Switzerland: Springer; 2018;1110:101–11.
IEEE
[1]
L. M. Georges, L. Verset, I. Zlobec, P. Demetter, and O. De Wever, “Impact of the microenvironment on tumour budding in colorectal cancer,” Advances in Experimental Medicine and Biology, vol. 1110, pp. 101–111, 2018.
@article{8591270,
  abstract     = {Tumour Budding (TB) is recognized as an adverse prognostic factor in colorectal cancer (CRC). TB is the detachment of isolated cancer cells or small clusters of such cells mainly at the invasion front. One question that arises is of the role of the tumour stroma regarding the permissiveness of the formation and progression of TB. In this review, we will examine potential factors affecting TB, in particular we will analyse the potential effect of inflammation, hypoxia, extracellular matrix and Cancer-Associated Fibroblasts (CAFs).},
  author       = {Georges, Laurent MC and Verset, Laurine and Zlobec, Inti and Demetter, Pieter and De Wever, Olivier},
  editor       = {Jordan, P},
  isbn         = {9783030027704},
  issn         = {0065-2598},
  journal      = {Advances in Experimental Medicine and Biology},
  keywords     = {Budding,Cancer-associated fibroblast,Epithelial-mesenchymal transition,Migration,Tumor-environment,CARCINOMA-ASSOCIATED FIBROBLASTS,MISMATCH REPAIR-PROFICIENT,LYMPH-NODE METASTASIS,EXPRESSION,MYOFIBROBLASTS,PROGRESSION,INVASION,STROMA,CELLS,COLON},
  language     = {eng},
  pages        = {101--111},
  publisher    = {Springer},
  title        = {Impact of the microenvironment on tumour budding in colorectal cancer},
  url          = {http://dx.doi.org/10.1007/978-3-030-02771-1_7},
  volume       = {1110},
  year         = {2018},
}

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