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Revisiting tubercidin against kinetoplastid parasites : aromatic substitutions at position 7 improve activity and reduce toxicity

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Keywords
7-Deazapurine nucleosides, Negishi cross coupling, Trypanosoma brucei brucei, Trypanosoma cruzi, SUBSTRATE RECOGNITION MOTIFS, TRYPANOSOMA-BRUCEI, DRUG-RESISTANCE, AFRICAN TRYPANOSOMIASIS, NUCLEOSIDE TRANSPORTER, CHEMICAL-SYNTHESIS, ADENOSINE KINASE, DIAMIDINE DRUGS, PURINE, INHIBITORS

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Citation

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Chicago
Hulpia, Fabian, Gustavo Daniel Campagnaro, Mirko Scortichini, Kristof Van Hecke, Louis Maes, Harry P de Koning, Guy Caljon, and Serge Van Calenbergh. 2019. “Revisiting Tubercidin Against Kinetoplastid Parasites : Aromatic Substitutions at Position 7 Improve Activity and Reduce Toxicity.” European Journal of Medicinal Chemistry 164: 689–705.
APA
Hulpia, F., Campagnaro, G. D., Scortichini, M., Van Hecke, K., Maes, L., de Koning, H. P., Caljon, G., et al. (2019). Revisiting tubercidin against kinetoplastid parasites : aromatic substitutions at position 7 improve activity and reduce toxicity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 164, 689–705.
Vancouver
1.
Hulpia F, Campagnaro GD, Scortichini M, Van Hecke K, Maes L, de Koning HP, et al. Revisiting tubercidin against kinetoplastid parasites : aromatic substitutions at position 7 improve activity and reduce toxicity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2019;164:689–705.
MLA
Hulpia, Fabian et al. “Revisiting Tubercidin Against Kinetoplastid Parasites : Aromatic Substitutions at Position 7 Improve Activity and Reduce Toxicity.” EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 164 (2019): 689–705. Print.
@article{8587157,
  author       = {Hulpia, Fabian and Campagnaro, Gustavo Daniel and Scortichini, Mirko and Van Hecke, Kristof and Maes, Louis and de Koning, Harry P and Caljon, Guy and Van Calenbergh, Serge},
  issn         = {0223-5234},
  journal      = {EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY},
  language     = {eng},
  pages        = {689--705},
  title        = {Revisiting tubercidin against kinetoplastid parasites : aromatic substitutions at position 7 improve activity and reduce toxicity},
  url          = {http://dx.doi.org/10.1016/j.ejmech.2018.12.050},
  volume       = {164},
  year         = {2019},
}

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