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Abstract
This paper introduces for the first time in literature the complete picture of depth of anesthesia regulatory paradigm. The simulation model proposes to include not only the three anesthesia features: hypnosis, analgesia and neuromuscular blockade, but also to introduce the interaction with the hemodynamic system (cardio-regulatory loops). Disturbances occurring in the operation theatre origin from surgical stimulation, for which profiles are available. A novel addition is the model of nociceptor pathway, recently developed and thus available for analysis. The nociceptor pathway model makes the link between the surgical stimulation and the perception to the patient of its effect. In conclusion, this paper presents a nonlinear multiple input multiple output model for further development of control algorithms in this application field.
Keywords
depth of anesthesia, nociceptor pathway, hemodynamic stabilisation, open loop, simulation, nonlinear model, INTENSIVE-CARE-UNIT, SELF-ORGANIZING FUZZY, CLOSED-LOOP CONTROL, NOXIOUS-STIMULATION, PROPOFOL ANESTHESIA, GENERAL-ANESTHESIA, ADAPTIVE-CONTROL, DRUG-DELIVERY, HYPNOSIS, DEPTH

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Citation

Please use this url to cite or link to this publication:

Chicago
Ionescu, Clara-Mihaela, Dana Copot, Martine Neckebroek, and Cristina I Muresan. 2018. “Anesthesia Regulation : Towards Completing the Picture.” In 2018 IEEE International Conference on Automation, Quality and Testing, Robotics (AQTR). New York, NY, USA: IEEE.
APA
Ionescu, C.-M., Copot, D., Neckebroek, M., & Muresan, C. I. (2018). Anesthesia regulation : towards completing the picture. 2018 IEEE International conference on automation, quality and testing, robotics (AQTR). Presented at the 21st IEEE International conference on Automation, Quality and Testing, Robotics (AQTR THETA), New York, NY, USA: IEEE.
Vancouver
1.
Ionescu C-M, Copot D, Neckebroek M, Muresan CI. Anesthesia regulation : towards completing the picture. 2018 IEEE International conference on automation, quality and testing, robotics (AQTR). New York, NY, USA: IEEE; 2018.
MLA
Ionescu, Clara-Mihaela, Dana Copot, Martine Neckebroek, et al. “Anesthesia Regulation : Towards Completing the Picture.” 2018 IEEE International Conference on Automation, Quality and Testing, Robotics (AQTR). New York, NY, USA: IEEE, 2018. Print.
@inproceedings{8584727,
  abstract     = {This paper introduces for the first time in literature the complete picture of depth of anesthesia regulatory paradigm. The simulation model proposes to include not only the three anesthesia features: hypnosis, analgesia and neuromuscular blockade, but also to introduce the interaction with the hemodynamic system (cardio-regulatory loops). Disturbances occurring in the operation theatre origin from surgical stimulation, for which profiles are available. A novel addition is the model of nociceptor pathway, recently developed and thus available for analysis. The nociceptor pathway model makes the link between the surgical stimulation and the perception to the patient of its effect. In conclusion, this paper presents a nonlinear multiple input multiple output model for further development of control algorithms in this application field.},
  author       = {Ionescu, Clara-Mihaela and Copot, Dana and Neckebroek, Martine and Muresan, Cristina I},
  booktitle    = {2018 IEEE International conference on automation, quality and testing, robotics (AQTR)},
  isbn         = {9781538622056},
  issn         = {1844-7872},
  language     = {eng},
  location     = {Cluj Napoca, Romania},
  pages        = {6},
  publisher    = {IEEE},
  title        = {Anesthesia regulation : towards completing the picture},
  year         = {2018},
}

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