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Psoriasis plays a wild CARD

Elien Van Nuffel (UGent) , Inna Afonina (UGent) and Rudi Beyaert (UGent)
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Abstract
Rare autosomal mutations in CARD14 have previously been linked to psoriasis susceptibility in humans, but their pathogenic role had not been shown. Mellett et al. generated mice harboring the patient-derived gain-of-function Card14DE138 mutation and showed that hyperactivation of CARD14 alone is sufficient to induce immunopathogenic mechanisms that are responsible for psoriasis, which is driven by the IL-17/IL-23 axis.

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Citation

Please use this url to cite or link to this publication:

MLA
Van Nuffel, Elien, Inna Afonina, and Rudi Beyaert. “Psoriasis Plays a Wild CARD.” JOURNAL OF INVESTIGATIVE DERMATOLOGY 2018 : 1903–1905. Print.
APA
Van Nuffel, E., Afonina, I., & Beyaert, R. (2018). Psoriasis plays a wild CARD. JOURNAL OF INVESTIGATIVE DERMATOLOGY.
Chicago author-date
Van Nuffel, Elien, Inna Afonina, and Rudi Beyaert. 2018. “Psoriasis Plays a Wild CARD.” Journal of Investigative Dermatology.
Chicago author-date (all authors)
Van Nuffel, Elien, Inna Afonina, and Rudi Beyaert. 2018. “Psoriasis Plays a Wild CARD.” Journal of Investigative Dermatology.
Vancouver
1.
Van Nuffel E, Afonina I, Beyaert R. Psoriasis plays a wild CARD. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018. p. 1903–5.
IEEE
[1]
E. Van Nuffel, I. Afonina, and R. Beyaert, “Psoriasis plays a wild CARD,” JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 138, no. 9. pp. 1903–1905, 2018.
@misc{8582804,
  abstract     = {Rare autosomal mutations in CARD14 have previously been linked to psoriasis susceptibility in humans, but their pathogenic role had not been shown. Mellett et al. generated mice harboring the patient-derived gain-of-function Card14DE138 mutation and showed that hyperactivation of CARD14 alone is sufficient to induce immunopathogenic mechanisms that are responsible for psoriasis, which is driven by the IL-17/IL-23 axis.},
  author       = {Van Nuffel, Elien and Afonina, Inna and Beyaert, Rudi},
  issn         = {0022-202X},
  language     = {eng},
  number       = {9},
  pages        = {1903--1905},
  series       = {JOURNAL OF INVESTIGATIVE DERMATOLOGY},
  title        = {Psoriasis plays a wild CARD},
  url          = {http://dx.doi.org/10.1016/j.jid.2018.05.001},
  volume       = {138},
  year         = {2018},
}

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