- Author
- Elien Van Nuffel (UGent) , Inna Afonina (UGent) and Rudi Beyaert (UGent)
- Organization
- Abstract
- Rare autosomal mutations in CARD14 have previously been linked to psoriasis susceptibility in humans, but their pathogenic role had not been shown. Mellett et al. generated mice harboring the patient-derived gain-of-function Card14DE138 mutation and showed that hyperactivation of CARD14 alone is sufficient to induce immunopathogenic mechanisms that are responsible for psoriasis, which is driven by the IL-17/IL-23 axis.
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8582804
- MLA
- Van Nuffel, Elien, Inna Afonina, and Rudi Beyaert. “Psoriasis Plays a Wild CARD.” JOURNAL OF INVESTIGATIVE DERMATOLOGY 2018 : 1903–1905. Print.
- APA
- Van Nuffel, E., Afonina, I., & Beyaert, R. (2018). Psoriasis plays a wild CARD. JOURNAL OF INVESTIGATIVE DERMATOLOGY.
- Chicago author-date
- Van Nuffel, Elien, Inna Afonina, and Rudi Beyaert. 2018. “Psoriasis Plays a Wild CARD.” Journal of Investigative Dermatology.
- Chicago author-date (all authors)
- Van Nuffel, Elien, Inna Afonina, and Rudi Beyaert. 2018. “Psoriasis Plays a Wild CARD.” Journal of Investigative Dermatology.
- Vancouver
- 1.Van Nuffel E, Afonina I, Beyaert R. Psoriasis plays a wild CARD. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018. p. 1903–5.
- IEEE
- [1]E. Van Nuffel, I. Afonina, and R. Beyaert, “Psoriasis plays a wild CARD,” JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 138, no. 9. pp. 1903–1905, 2018.
@misc{8582804, abstract = {Rare autosomal mutations in CARD14 have previously been linked to psoriasis susceptibility in humans, but their pathogenic role had not been shown. Mellett et al. generated mice harboring the patient-derived gain-of-function Card14DE138 mutation and showed that hyperactivation of CARD14 alone is sufficient to induce immunopathogenic mechanisms that are responsible for psoriasis, which is driven by the IL-17/IL-23 axis.}, author = {Van Nuffel, Elien and Afonina, Inna and Beyaert, Rudi}, issn = {0022-202X}, language = {eng}, number = {9}, pages = {1903--1905}, series = {JOURNAL OF INVESTIGATIVE DERMATOLOGY}, title = {Psoriasis plays a wild CARD}, url = {http://dx.doi.org/10.1016/j.jid.2018.05.001}, volume = {138}, year = {2018}, }
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