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LNCipedia 5 : towards a reference set of human long non-coding RNAs

Pieter-Jan Volders (UGent) , Jasper Anckaert (UGent) , Kenneth Verheggen (UGent) , Justine Nuytens (UGent) , Lennart Martens (UGent) , Pieter Mestdagh (UGent) and Jo Vandesompele (UGent)
(2019) NUCLEIC ACIDS RESEARCH. 47(D1). p.D135-D139
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Abstract
While long non-coding RNA (lncRNA) research in the past has primarily focused on the discovery of novel genes, today it has shifted towards functional annotation of this large class of genes. With thousands of lncRNA studies published every year, the current challenge lies in keeping track of which lncRNAs are functionally described. This is further complicated by the fact that lncRNA nomenclature is not straightforward and lncRNA annotation is scattered across different resources with their own quality metrics and definition of a lncRNA. To overcome this issue, large scale curation and annotation is needed. Here, we present the fifth release of the human lncRNA database LNCipedia (https://lncipedia.org). The most notable improvements include manual literature curation of 2482 lncRNA articles and the use of official gene symbols when available. In addition, an improved filtering pipeline results in a higher quality reference lncRNA gene set.
Keywords
DATABASE, ANNOTATION, VISUALIZATION, LANDSCAPE, GENCODE, ATLAS

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Please use this url to cite or link to this publication:

MLA
Volders, Pieter-Jan et al. “LNCipedia 5 : Towards a Reference Set of Human Long Non-coding RNAs.” NUCLEIC ACIDS RESEARCH 47.D1 (2019): D135–D139. Print.
APA
Volders, P.-J., Anckaert, J., Verheggen, K., Nuytens, J., Martens, L., Mestdagh, P., & Vandesompele, J. (2019). LNCipedia 5 : towards a reference set of human long non-coding RNAs. NUCLEIC ACIDS RESEARCH, 47(D1), D135–D139.
Chicago author-date
Volders, Pieter-Jan, Jasper Anckaert, Kenneth Verheggen, Justine Nuytens, Lennart Martens, Pieter Mestdagh, and Jo Vandesompele. 2019. “LNCipedia 5 : Towards a Reference Set of Human Long Non-coding RNAs.” Nucleic Acids Research 47 (D1): D135–D139.
Chicago author-date (all authors)
Volders, Pieter-Jan, Jasper Anckaert, Kenneth Verheggen, Justine Nuytens, Lennart Martens, Pieter Mestdagh, and Jo Vandesompele. 2019. “LNCipedia 5 : Towards a Reference Set of Human Long Non-coding RNAs.” Nucleic Acids Research 47 (D1): D135–D139.
Vancouver
1.
Volders P-J, Anckaert J, Verheggen K, Nuytens J, Martens L, Mestdagh P, et al. LNCipedia 5 : towards a reference set of human long non-coding RNAs. NUCLEIC ACIDS RESEARCH. 2019;47(D1):D135–D139.
IEEE
[1]
P.-J. Volders et al., “LNCipedia 5 : towards a reference set of human long non-coding RNAs,” NUCLEIC ACIDS RESEARCH, vol. 47, no. D1, pp. D135–D139, 2019.
@article{8580215,
  abstract     = {While long non-coding RNA (lncRNA) research in the past has primarily focused on the discovery of novel genes, today it has shifted towards functional annotation of this large class of genes. With thousands of lncRNA studies published every year, the current challenge lies in keeping track of which lncRNAs are functionally described. This is further complicated by the fact that lncRNA nomenclature is not straightforward and lncRNA annotation is scattered across different resources with their own quality metrics and definition of a lncRNA. To overcome this issue, large scale curation and annotation is needed. Here, we present the fifth release of the human lncRNA database LNCipedia (https://lncipedia.org). The most notable improvements include manual literature curation of 2482 lncRNA articles and the use of official gene symbols when available. In addition, an improved filtering pipeline results in a higher quality reference lncRNA gene set.},
  author       = {Volders, Pieter-Jan and Anckaert, Jasper and Verheggen, Kenneth and Nuytens, Justine and Martens, Lennart and Mestdagh, Pieter and Vandesompele, Jo},
  issn         = {0305-1048},
  journal      = {NUCLEIC ACIDS RESEARCH},
  keywords     = {DATABASE,ANNOTATION,VISUALIZATION,LANDSCAPE,GENCODE,ATLAS},
  language     = {eng},
  number       = {D1},
  pages        = {D135--D139},
  title        = {LNCipedia 5 : towards a reference set of human long non-coding RNAs},
  url          = {http://dx.doi.org/10.1093/nar/gky1031},
  volume       = {47},
  year         = {2019},
}

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