@article{8571475,
  abstract     = {{Natural killer (NK) cells play an important role in the host response against viral infections and cancer development. They are able to kill virus-infected and tumor cells, and they produce different important cytokines that stimulate the antiviral and antitumor adaptive immune response, particularly interferon gamma. NK cells are of particular importance in herpesvirus infections, which is illustrated by systemic and life-threatening herpesvirus disease symptoms in patients with deficiencies in NK cell activity and by the myriad of reports describing herpesvirus NK cell evasion strategies. The latter is particularly obvious for cytomegaloviruses, but increasing evidence indicates that most, if not all, members of the herpesvirus family suppress NK cell activity to some extent. This review discusses the different NK cell evasion strategies described for herpesviruses and how this knowledge may translate to clinical applications.}},
  articleno    = {{e02105-17}},
  author       = {{De Pelsmaeker, Steffi and Romero Rata, Nicolás and Vitale, Massimo and Favoreel, Herman}},
  issn         = {{0022-538X}},
  journal      = {{JOURNAL OF VIROLOGY}},
  keywords     = {{EBV,KSHV,NK cell,cytomegalovirus,evasion,herpesvirus,herpes simplex virus,natural killer cells,pseudorabies virus,VIRUS-INFECTED CELLS,CYTOMEGALOVIRUS UL16 GLYCOPROTEIN,MISSING SELF-RECOGNITION,NKG2D LIGAND EXPRESSION,VARICELLA-ZOSTER-VIRUS,I-RELATED MOLECULES,NK CELLS,HLA-E,MURINE CYTOMEGALOVIRUS,DOWN-REGULATION}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{19}},
  title        = {{Herpesvirus evasion of natural killer cells}},
  url          = {{http://doi.org/10.1128/jvi.02105-17}},
  volume       = {{92}},
  year         = {{2018}},
}

Altmetric

View in Altmetric

Web of Science

Times cited: