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Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

(2018) MICROBIAL CELL. 5(7). p.300-326
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Organization
Abstract
Unlike superficial fungal infections of the skin and nails, which are the most common fungal diseases in humans, invasive fungal infections carry high morbidity and mortality, particularly those associated with biofilm formation on indwelling medical devices. Therapeutic management of these complex diseases is often complicated by the rise in resistance to the commonly used antifungal agents. Therefore, the availability of accurate susceptibility testing methods for determining antifungal resistance, as well as discovery of novel antifungal and antibiofilm agents, are key priorities in medical mycology research. To direct advancements in this field, here we present an overview of the methods currently available for determining (i) the susceptibility or resistance of fungal isolates or biofilms to antifungal or antibiofilm compounds and compound combinations; (ii) the in vivo efficacy of antifungal and antibiofilm compounds and compound combinations; and (iii) the in vitro and in vivo performance of anti-infective coatings and materials to prevent fungal biofilm-based infections.
Keywords
CANDIDA-ALBICANS BIOFILMS, GUINEA-PIG MODEL, MINIMUM FUNGICIDAL, CONCENTRATIONS, INVASIVE PULMONARY ASPERGILLOSIS, GALLERIA-MELLONELLA, LARVAE, VULVO-VAGINAL CANDIDIASIS, OXYSPORUM SPECIES COMPLEX, LIPOSOMAL, AMPHOTERICIN-B, RAT SUBCUTANEOUS MODEL, HUMAN-PATHOGENIC FUNGI, antifungal susceptibility testing, biofilm inhibition, biofilm, eradication, antibiofilm material coating, in vivo models

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Citation

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MLA
Van Dijck, Patrick, Jelmer Sjollema, Bruno Cammue, et al. “Methodologies for in Vitro and in Vivo Evaluation of Efficacy of Antifungal and Antibiofilm Agents and Surface Coatings Against Fungal Biofilms.” MICROBIAL CELL 5.7 (2018): 300–326. Print.
APA
Van Dijck, Patrick, Sjollema, J., Cammue, B., Lagrou, K., Berman, J., d’ Enfert, C., Andes, D. R., et al. (2018). Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. MICROBIAL CELL, 5(7), 300–326.
Chicago author-date
Van Dijck, Patrick, Jelmer Sjollema, Bruno Cammue, Katrien Lagrou, Judith Berman, Christophe d’ Enfert, David R Andes, et al. 2018. “Methodologies for in Vitro and in Vivo Evaluation of Efficacy of Antifungal and Antibiofilm Agents and Surface Coatings Against Fungal Biofilms.” Microbial Cell 5 (7): 300–326.
Chicago author-date (all authors)
Van Dijck, Patrick, Jelmer Sjollema, Bruno Cammue, Katrien Lagrou, Judith Berman, Christophe d’ Enfert, David R Andes, Maiken C Arendrup, Axel A Brakhage, Richard Calderone, Emilia Canton, Tom Coenye, Paul Cos, Leah E Cowen, Mira Edgerton, Ana Espinel-Ingroff, Scott G Filler, Mahmoud Ghannoum, Neil AR Gow, Hubertus Haas, Mary Ann Jabra-Rizk, Elizabeth M Johnson, Shawn R Lockhart, Jose L Lopez-Ribot, Johan Maertens, Carol A Munro, Jeniel E Nett, Clarissa J Nobile, Michael A Pfaller, Gordon Ramage, Dominique Sanglard, Maurizio Sanguinetti, Isabel Spriet, Paul E Verweij, Adilia Warris, Joost Wauters, Michael R Yeaman, Sebastian AJ Zaat, and Karin Thevissen. 2018. “Methodologies for in Vitro and in Vivo Evaluation of Efficacy of Antifungal and Antibiofilm Agents and Surface Coatings Against Fungal Biofilms.” Microbial Cell 5 (7): 300–326.
Vancouver
1.
Van Dijck P, Sjollema J, Cammue B, Lagrou K, Berman J, d’ Enfert C, et al. Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms. MICROBIAL CELL. 2018;5(7):300–26.
IEEE
[1]
P. Van Dijck et al., “Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms,” MICROBIAL CELL, vol. 5, no. 7, pp. 300–326, 2018.
@article{8571439,
  abstract     = {Unlike superficial fungal infections of the skin and nails, which are the most common fungal diseases in humans, invasive fungal infections carry high morbidity and mortality, particularly those associated with biofilm formation on indwelling medical devices. Therapeutic management of these complex diseases is often complicated by the rise in resistance to the commonly used antifungal agents. Therefore, the availability of accurate susceptibility testing methods for determining antifungal resistance, as well as discovery of novel antifungal and antibiofilm agents, are key priorities in medical mycology research. To direct advancements in this field, here we present an overview of the methods currently available for determining (i) the susceptibility or resistance of fungal isolates or biofilms to antifungal or antibiofilm compounds and compound combinations; (ii) the in vivo efficacy of antifungal and antibiofilm compounds and compound combinations; and (iii) the in vitro and in vivo performance of anti-infective coatings and materials to prevent fungal biofilm-based infections.},
  author       = {Van Dijck, Patrick and Sjollema, Jelmer and Cammue, Bruno and Lagrou, Katrien and Berman, Judith and d'Enfert, Christophe and Andes, David R and Arendrup, Maiken C and Brakhage, Axel A and Calderone, Richard and Canton, Emilia and Coenye, Tom and Cos, Paul and Cowen, Leah E and Edgerton, Mira and Espinel-Ingroff, Ana and Filler, Scott G and Ghannoum, Mahmoud and Gow, Neil AR and Haas, Hubertus and Jabra-Rizk, Mary Ann and Johnson, Elizabeth M and Lockhart, Shawn R and Lopez-Ribot, Jose L and Maertens, Johan and Munro, Carol A and Nett, Jeniel E and Nobile, Clarissa J and Pfaller, Michael A and Ramage, Gordon and Sanglard, Dominique and Sanguinetti, Maurizio and Spriet, Isabel and Verweij, Paul E and Warris, Adilia and Wauters, Joost and Yeaman, Michael R and Zaat, Sebastian AJ and Thevissen, Karin},
  issn         = {2311-2638},
  journal      = {MICROBIAL CELL},
  keywords     = {CANDIDA-ALBICANS BIOFILMS,GUINEA-PIG MODEL,MINIMUM FUNGICIDAL,CONCENTRATIONS,INVASIVE PULMONARY ASPERGILLOSIS,GALLERIA-MELLONELLA,LARVAE,VULVO-VAGINAL CANDIDIASIS,OXYSPORUM SPECIES COMPLEX,LIPOSOMAL,AMPHOTERICIN-B,RAT SUBCUTANEOUS MODEL,HUMAN-PATHOGENIC FUNGI,antifungal susceptibility testing,biofilm inhibition,biofilm,eradication,antibiofilm material coating,in vivo models},
  language     = {eng},
  number       = {7},
  pages        = {300--326},
  title        = {Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms},
  url          = {http://dx.doi.org/10.15698/mic2018.07.638},
  volume       = {5},
  year         = {2018},
}

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