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Sophorolipid modification : the power of yeasts and enzymes

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Abstract
Sophorolipids are biosurfactants or biological detergents composed of a hydroxylated fatty acid and the glucose disaccharide sophorose. These commercially relevant molecules are produced by the yeast Starmerella bombicola and offer a green and renewable alternative for traditional surfactants. To further broaden up the application potential of sophorolipids, introduction of structural variation is essential as this influences their physicochemical and biological properties. However, creating molecular variants is not as straightforward as for petrochemically derived surfactants. This is, on the one hand, a consequence of the biological origin and restricting biochemistry behind it, and is, on the other hand, caused by the complexity of chemical processes regarding the necessity of protection and deprotection of the glucose units. In this chapter, several strategies to overcome these limitations will be discussed, such as the use of special substrates during yeast cultivation, design of engineered strains, and enzymatic modification.
Keywords
enzymatic modification, lipase, Novozym 435, sophorolipid, Starmerella bombicola, strain engineering, yeast

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Chicago
Delbeke, Elisabeth, Kevin Van Geem, C.V. Stevens, and I.N.A. Van Bogaert. 2018. “Sophorolipid Modification : the Power of Yeasts and Enzymes.” In Lipid Modification by Enzymes and Engineered Microbes, ed. Uwe T. Bornscheuer, 315–341. AOCS Press .
APA
Delbeke, E., Van Geem, K., Stevens, C. V., & Van Bogaert, I. N. A. (2018). Sophorolipid modification : the power of yeasts and enzymes. In U. T. Bornscheuer (Ed.), Lipid modification by enzymes and engineered microbes (pp. 315–341). AOCS Press .
Vancouver
1.
Delbeke E, Van Geem K, Stevens CV, Van Bogaert INA. Sophorolipid modification : the power of yeasts and enzymes. In: Bornscheuer UT, editor. Lipid modification by enzymes and engineered microbes. AOCS Press ; 2018. p. 315–41.
MLA
Delbeke, Elisabeth, Kevin Van Geem, C.V. Stevens, et al. “Sophorolipid Modification : the Power of Yeasts and Enzymes.” Lipid Modification by Enzymes and Engineered Microbes. Ed. Uwe T. Bornscheuer. AOCS Press , 2018. 315–341. Print.
@incollection{8565002,
  abstract     = {Sophorolipids are biosurfactants or biological detergents composed of a hydroxylated fatty acid and the glucose disaccharide sophorose. These commercially relevant molecules are produced by the yeast Starmerella bombicola and offer a green and renewable alternative for traditional surfactants.

To further broaden up the application potential of sophorolipids, introduction of structural variation is essential as this influences their physicochemical and biological properties. However, creating molecular variants is not as straightforward as for petrochemically derived surfactants. This is, on the one hand, a consequence of the biological origin and restricting biochemistry behind it, and is, on the other hand, caused by the complexity of chemical processes regarding the necessity of protection and deprotection of the glucose units.

In this chapter, several strategies to overcome these limitations will be discussed, such as the use of special substrates during yeast cultivation, design of engineered strains, and enzymatic modification.},
  author       = {Delbeke, Elisabeth and Van Geem, Kevin and Stevens, C.V. and Van Bogaert, I.N.A.},
  booktitle    = {Lipid modification by enzymes and engineered microbes},
  editor       = {Bornscheuer, Uwe T.},
  isbn         = { 978-0-12-813167-1},
  keyword      = {enzymatic modification,lipase,Novozym 435,sophorolipid,Starmerella bombicola,strain engineering,yeast},
  language     = {eng},
  pages        = {315--341},
  publisher    = {AOCS Press },
  title        = {Sophorolipid modification : the power of yeasts and enzymes},
  url          = {http://dx.doi.org/10.1016/B978-0-12-813167-1.00014-1},
  year         = {2018},
}

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