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Antibacterial and immunomodulatory activities of bovine lactoferrin against Escherichia coli O157:H7 infections in cattle

Evelien Kieckens (UGent) , Joanna Rybarczyk (UGent) , Eric Cox (UGent) and Daisy Vanrompay (UGent)
(2018) BIOMETALS. 31(3). p.321-330
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Abstract
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a zoonotic pathogen that causes food-borne disease in humans ranging from watery diarrhea to bloody diarrhea and severe hemorrhagic colitis, renal failure and hemolytic uremic syndrome. Cattle, the most important source of E. coli O157:H7 transmission to humans, harbor the bacteria in their gastrointestinal tract without showing clinical symp- toms. Prevention of E. coli O157:H7 infections in ruminants could diminish the public health risk. However, there is no specific treatment available nor a vaccine or a therapeutic agent which completely prevents E. coli O157:H7 infections in cattle. This paper provides an overview of latest research data on eradicating enterohemorrhagic E. coli O157:H7 in ruminants by use of bovine lactoferrin administration.
Keywords
Cattle, Escherichia coli O157:H7, Bovine lactoferrin, Rectal administration, Shiga toxin, Interleukin 6, INTESTINAL EPITHELIAL-CELLS, HEAT-TREATMENT, O157-H7, PREVALENCE, COLONIZATION, PEPTIDE, BINDING, CALVES, LIPOPOLYSACCHARIDE, IDENTIFICATION

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Chicago
Kieckens, Evelien, Joanna Rybarczyk, Eric Cox, and Daisy Vanrompay. 2018. “Antibacterial and Immunomodulatory Activities of Bovine Lactoferrin Against Escherichia Coli O157:H7 Infections in Cattle.” Biometals 31 (3): 321–330.
APA
Kieckens, E., Rybarczyk, J., Cox, E., & Vanrompay, D. (2018). Antibacterial and immunomodulatory activities of bovine lactoferrin against Escherichia coli O157:H7 infections in cattle. BIOMETALS, 31(3), 321–330. Presented at the 13th International conference on Lactoferrin, Structure Function and Applications.
Vancouver
1.
Kieckens E, Rybarczyk J, Cox E, Vanrompay D. Antibacterial and immunomodulatory activities of bovine lactoferrin against Escherichia coli O157:H7 infections in cattle. BIOMETALS. 2018;31(3):321–30.
MLA
Kieckens, Evelien, Joanna Rybarczyk, Eric Cox, et al. “Antibacterial and Immunomodulatory Activities of Bovine Lactoferrin Against Escherichia Coli O157:H7 Infections in Cattle.” BIOMETALS 31.3 (2018): 321–330. Print.
@article{8563045,
  abstract     = {Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a zoonotic pathogen that causes food-borne disease in humans ranging from watery diarrhea to bloody diarrhea and severe hemorrhagic colitis, renal failure and hemolytic uremic syndrome. Cattle, the most important source of E. coli O157:H7 transmission to humans, harbor the bacteria in their gastrointestinal tract without showing clinical symp- toms. Prevention of E. coli O157:H7 infections in ruminants could diminish the public health risk. However, there is no specific treatment available nor a vaccine or a therapeutic agent which completely prevents E. coli O157:H7 infections in cattle. This paper provides an overview of latest research data on eradicating enterohemorrhagic E. coli O157:H7 in ruminants by use of bovine lactoferrin administration.},
  author       = {Kieckens, Evelien and Rybarczyk, Joanna and Cox, Eric and Vanrompay, Daisy},
  issn         = {0966-0844},
  journal      = {BIOMETALS},
  language     = {eng},
  location     = {Rome, Italy},
  number       = {3},
  pages        = {321--330},
  title        = {Antibacterial and immunomodulatory activities of bovine lactoferrin against Escherichia coli O157:H7 infections in cattle},
  url          = {http://dx.doi.org/10.1007/s10534-018-0082-x},
  volume       = {31},
  year         = {2018},
}

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