@article{8562964,
  abstract     = {{Wnt proteins form a family of highly conserved secreted molecules that are critical mediators of cell-cell signaling during embryogenesis. Partial data on Wnt activity in different tissues and at different stages have been reported in frog embryos. Our objective here is to provide a coherent and detailed description of Wnt activity throughout embryo development. Using a transgenic Xenopus tropicalis line carrying a Wnt-responsive reporter sequence, we depict the spatial and temporal dynamics of canonical Wnt activity during embryogenesis. We provide a comprehensive series of in situ hybridization in whole-mount embryos and in cross-sections, from gastrula to tadpole stages, with special focus on neural tube, retina and neural crest cell development. This collection of patterns will thus constitute a valuable resource for developmental biologists to picture the dynamics of Wnt activity during development.}},
  articleno    = {{e0193606}},
  author       = {{Borday, Caroline and Parain, Karine and Tran Thi, Hong and Vleminckx, Kris and Perron, Muriel and Monsoro-Burq, Anne H}},
  issn         = {{1932-6203}},
  journal      = {{PLOS ONE}},
  keywords     = {{NEURAL CREST INDUCTION,CYCLIN D1 GENE,BETA-CATENIN,SIGNALING,PATHWAYS,CILIARY MARGIN,PLATE BORDER,STEM-CELLS,OPTIC CUP,EXPRESSION,ZEBRAFISH}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{19}},
  title        = {{An atlas of Wnt activity during embryogenesis in Xenopus tropicalis}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0193606}},
  volume       = {{13}},
  year         = {{2018}},
}

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