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Abstract
The number of octogenarians is growing which results in increasing number of people with multimorbidity. Multimorbidity creates polypharmacy, which, consequently, is the most consistent predictor of inappropriate prescribing and drugrelated problems (DRPs) in older people. In this chapter, the main characteristics of polypharmacy and the risks for DRPs, with focus on prescribing cascade and drug interactions, are described. Subsequently, steps to be considered during prescribing for older persons, methods for detecting DRPs and optimisation of polypharmacy are elaborated on. This chapter provides insights on assessment of pharmacotherapy in older patients, detection of potential DRPs, optimal solutions for the detected problems and tailoring pharmacotherapy to the profile, the needs and the goals of care in older patients.
Keywords
pharmacotherapy, older people, polypharmacy, drug related problems

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Chicago
Petrovic, Mirko, Danijela Gnjidic, Eline Tommelein, and Koen Boussery. 2018. “Pharmacotherapy.” In Learning Geriatric Medicine : a Study Guide for Medical Students, ed. Regina Roller-Wirnsberger, Katrin Singler, and Maria Cristina Polidori, 219–235. Cham, Switzerland: Springer.
APA
Petrovic, M., Gnjidic, D., Tommelein, E., & Boussery, K. (2018). Pharmacotherapy. In R. Roller-Wirnsberger, K. Singler, & M. C. Polidori (Eds.), Learning geriatric medicine : a study guide for medical students (pp. 219–235). Cham, Switzerland: Springer.
Vancouver
1.
Petrovic M, Gnjidic D, Tommelein E, Boussery K. Pharmacotherapy. In: Roller-Wirnsberger R, Singler K, Polidori MC, editors. Learning geriatric medicine : a study guide for medical students. Cham, Switzerland: Springer; 2018. p. 219–35.
MLA
Petrovic, Mirko, Danijela Gnjidic, Eline Tommelein, et al. “Pharmacotherapy.” Learning Geriatric Medicine : a Study Guide for Medical Students. Ed. Regina Roller-Wirnsberger, Katrin Singler, & Maria Cristina Polidori. Cham, Switzerland: Springer, 2018. 219–235. Print.
@incollection{8559187,
  abstract     = {The number of octogenarians is growing which results in increasing number of people with multimorbidity. Multimorbidity creates polypharmacy, which, consequently, is the most consistent predictor of inappropriate prescribing and drugrelated problems (DRPs) in older people. In this chapter, the main characteristics of polypharmacy and the risks for DRPs, with focus on prescribing cascade and drug interactions, are described. Subsequently, steps to be considered during prescribing for older persons, methods for detecting DRPs and optimisation of polypharmacy are elaborated on. This chapter provides insights on assessment of pharmacotherapy in older patients, detection of potential DRPs, optimal solutions for the detected problems and tailoring pharmacotherapy to the profile, the needs and the goals of care in older patients.},
  author       = {Petrovic, Mirko and Gnjidic, Danijela and Tommelein, Eline and Boussery, Koen},
  booktitle    = {Learning geriatric medicine : a study guide for medical students},
  editor       = {Roller-Wirnsberger, Regina and Singler, Katrin and Polidori, Maria Cristina},
  isbn         = {9783319619965},
  issn         = {2509-6060},
  keyword      = {pharmacotherapy,older people,polypharmacy,drug related problems},
  language     = {eng},
  pages        = {219--235},
  publisher    = {Springer},
  series       = {Practical Issues in Geriatrics},
  title        = {Pharmacotherapy},
  url          = {http://dx.doi.org/10.1007/978-3-319-61997-2\_23},
  year         = {2018},
}

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