Advanced search
1 file | 131.47 KB

Detomidine and butorphanol for standing sedation in a range of zoo-kept ungulate species

Author
Organization
Abstract
General anesthesia poses risks for larger zoo species, like cardiorespiratory depression, myopathy, and hyperthermia. In ruminants, ruminal bloat and regurgitation of rumen contents with potential aspiration pneumonia are added risks. Thus, the use of sedation to perform minor procedures is justified in zoo animals. A combination of detomidine and butorphanol has been routinely used in domestic animals. This drug combination, administered by remote intramuscular injection, can also be applied for standing sedation in a range of zoo animals, allowing a number of minor procedures. The combination was successfully administered in five species of nondomesticated equids (Przewalski horse [Equus ferus przewalskii; n = 1], onager [Equus hemionus onager; n = 4], kiang [Equus kiang; n = 3], Grevy's zebra [Equus grevyi; n = 4], and Somali wild ass [Equus africanus somaliensis; n = 7]), with a mean dose range of 0.10-0.17 mg/kg detomidine and 0.07-0.13 mg/kg butorphanol; the white (Ceratotherium simum simum; n = 12) and greater one-horned rhinoceros (Rhinoceros unicornis; n = 4), with a mean dose of 0.015 mg/kg of both detomidine and butorphanol; and Asiatic elephant bulls (Elephas maximus; n = 2), with a mean dose of 0.018 mg/kg of both detomidine and butorphanol. In addition, the combination was successfully used for standing sedation in six species of artiodactylids: giraffe (Giraffa camelopardalis reticulata; n = 3), western bongo (Tragelaphus eurycerus eurycerus; n = 2), wisent (Bison bonasus; n = 5), yak (Bos grunniens; n = 1), water buffalo (Bubalus bubalis; n = 4) and Bactrian camel (Camelus bactrianus; n = 5). The mean dose range for artiodactylid species except bongo was 0.04-0.06 mg/kg detomidine and 0.03-0.06 mg/kg butorphanol. The dose in bongo, 0.15-0.20 mg/kg detomidine and 0.13-0.15 mg/kg butorphanol, was considerably higher. Times to first effect, approach, and recovery after antidote were short. The use of detomidine and butorphanol has been demonstrated to be a reliable, safe alternative to general anesthesia for a number of large ungulate species.
Keywords
Artiodactyl, butorphanol, detomidine, equid, mega herbivores, standing sedation, CAMELS CAMELUS-DROMEDARIUS, ELEPHANT ELEPHAS-MAXIMUS, CERATOTHERIUM-SIMUM, ALPHA(2) AGONISTS, XYLAZINE, HORSES, MEDETOMIDINE, RHINOCEROS, ANESTHESIA, CATTLE

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 131.47 KB

Citation

Please use this url to cite or link to this publication:

Chicago
Bouts, Tim, Joanne Dodds, Karla Berry, Abdi Arif, Polly Taylor, Andrew Routh, and Frank Gasthuys. 2017. “Detomidine and Butorphanol for Standing Sedation in a Range of Zoo-kept Ungulate Species.” Journal of Zoo and Wildlife Medicine 48 (3): 616–626.
APA
Bouts, Tim, Dodds, J., Berry, K., Arif, A., Taylor, P., Routh, A., & Gasthuys, F. (2017). Detomidine and butorphanol for standing sedation in a range of zoo-kept ungulate species. JOURNAL OF ZOO AND WILDLIFE MEDICINE, 48(3), 616–626.
Vancouver
1.
Bouts T, Dodds J, Berry K, Arif A, Taylor P, Routh A, et al. Detomidine and butorphanol for standing sedation in a range of zoo-kept ungulate species. JOURNAL OF ZOO AND WILDLIFE MEDICINE. 2017;48(3):616–26.
MLA
Bouts, Tim, Joanne Dodds, Karla Berry, et al. “Detomidine and Butorphanol for Standing Sedation in a Range of Zoo-kept Ungulate Species.” JOURNAL OF ZOO AND WILDLIFE MEDICINE 48.3 (2017): 616–626. Print.
@article{8556451,
  abstract     = {General anesthesia poses risks for larger zoo species, like cardiorespiratory depression, myopathy, and hyperthermia. In ruminants, ruminal bloat and regurgitation of rumen contents with potential aspiration pneumonia are added risks. Thus, the use of sedation to perform minor procedures is justified in zoo animals. A combination of detomidine and butorphanol has been routinely used in domestic animals. This drug combination, administered by remote intramuscular injection, can also be applied for standing sedation in a range of zoo animals, allowing a number of minor procedures. The combination was successfully administered in five species of nondomesticated equids (Przewalski horse [Equus ferus przewalskii; n = 1], onager [Equus hemionus onager; n = 4], kiang [Equus kiang; n = 3], Grevy's zebra [Equus grevyi; n = 4], and Somali wild ass [Equus africanus somaliensis; n = 7]), with a mean dose range of 0.10-0.17 mg/kg detomidine and 0.07-0.13 mg/kg butorphanol; the white (Ceratotherium simum simum; n = 12) and greater one-horned rhinoceros (Rhinoceros unicornis; n = 4), with a mean dose of 0.015 mg/kg of both detomidine and butorphanol; and Asiatic elephant bulls (Elephas maximus; n = 2), with a mean dose of 0.018 mg/kg of both detomidine and butorphanol. In addition, the combination was successfully used for standing sedation in six species of artiodactylids: giraffe (Giraffa camelopardalis reticulata; n = 3), western bongo (Tragelaphus eurycerus eurycerus; n = 2), wisent (Bison bonasus; n = 5), yak (Bos grunniens; n = 1), water buffalo (Bubalus bubalis; n = 4) and Bactrian camel (Camelus bactrianus; n = 5). The mean dose range for artiodactylid species except bongo was 0.04-0.06 mg/kg detomidine and 0.03-0.06 mg/kg butorphanol. The dose in bongo, 0.15-0.20 mg/kg detomidine and 0.13-0.15 mg/kg butorphanol, was considerably higher. Times to first effect, approach, and recovery after antidote were short. The use of detomidine and butorphanol has been demonstrated to be a reliable, safe alternative to general anesthesia for a number of large ungulate species.},
  author       = {Bouts, Tim and Dodds, Joanne and Berry, Karla and Arif, Abdi and Taylor, Polly and Routh, Andrew and Gasthuys, Frank},
  issn         = {1042-7260},
  journal      = {JOURNAL OF ZOO AND WILDLIFE MEDICINE},
  language     = {eng},
  number       = {3},
  pages        = {616--626},
  title        = {Detomidine and butorphanol for standing sedation in a range of zoo-kept ungulate species},
  url          = {http://dx.doi.org/10.1638/2016-0047.1},
  volume       = {48},
  year         = {2017},
}

Altmetric
View in Altmetric
Web of Science
Times cited: