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The Intensive Care Medicine research agenda on critically ill oncology and hematology patients

(2017) INTENSIVE CARE MEDICINE. 43(9). p.1366-1382
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Abstract
Over the coming years, accelerating progress against cancer will be associated with an increased number of patients who require life-sustaining therapies for infectious or toxic chemotherapy-related events. Major changes include increased number of cancer patients admitted to the ICU with full-code status or for time-limited trials, increased survival and quality of life in ICU survivors, changing prognostic factors, early ICU admission for optimal monitoring, and use of noninvasive diagnostic and therapeutic strategies. In this review, experts in the management of critically ill cancer patients highlight recent changes in the use and the results of intensive care in patients with malignancies. They seek to put forward a standard of care for the management of these patients and highlight important updates that are required to care for them. The research agenda they suggest includes important studies to be conducted in the next few years to increase our understanding of organ dysfunction in this population and to improve our ability to appropriately use life-saving therapies or select new therapeutic approaches that are likely to improve outcomes. This review aims to provide more guidance for the daily management of patients with cancer, in whom outcomes are constantly improving, as is our global ability to fight against what is becoming the leading cause of mortality in industrialized and non-industrialized countries.
Keywords
Neutropenia, Bone marrow transplantation, Mechanical ventilation, Oxygen, Acute respiratory failure, Septic shock, Cancer, Bronchoscopy, ACUTE RESPIRATORY-FAILURE, ACUTE LUNG INJURY, STEM-CELL TRANSPLANTATION, INFECTIOUS-DISEASES SOCIETY, RANDOMIZED-CONTROLLED-TRIAL, COLONY-STIMULATING FACTOR, RAPID RESPONSE SYSTEMS, ACUTE MYELOID-LEUKEMIA, ACUTE KIDNEY INJURY, LONG-TERM SURVIVAL

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MLA
Azoulay, Elie, Peter Schellongowski, Michael Darmon, et al. “The Intensive Care Medicine Research Agenda on Critically Ill Oncology and Hematology Patients.” INTENSIVE CARE MEDICINE 43.9 (2017): 1366–1382. Print.
APA
Azoulay, Elie, Schellongowski, P., Darmon, M., Bauer, P. R., Benoit, D., Depuydt, P., Divatia, J. V., et al. (2017). The Intensive Care Medicine research agenda on critically ill oncology and hematology patients. INTENSIVE CARE MEDICINE, 43(9), 1366–1382.
Chicago author-date
Azoulay, Elie, Peter Schellongowski, Michael Darmon, Philippe R Bauer, Dominique Benoit, Pieter Depuydt, Jigeeshu V Divatia, et al. 2017. “The Intensive Care Medicine Research Agenda on Critically Ill Oncology and Hematology Patients.” Intensive Care Medicine 43 (9): 1366–1382.
Chicago author-date (all authors)
Azoulay, Elie, Peter Schellongowski, Michael Darmon, Philippe R Bauer, Dominique Benoit, Pieter Depuydt, Jigeeshu V Divatia, Virginie Lemiale, Maarten van Vliet, Anne-Pascale Meert, Djamel Mokart, Stephen M Pastores, Anders Perner, Frédéric Pène, Peter Pickkers, Kathryn A Puxty, Francois Vincent, Jorge Salluh, Ayman O Soubani, Massimo Antonelli, Thomas Staudinger, Michael von Bergwelt-Baildon, and Marcio Soares. 2017. “The Intensive Care Medicine Research Agenda on Critically Ill Oncology and Hematology Patients.” Intensive Care Medicine 43 (9): 1366–1382.
Vancouver
1.
Azoulay E, Schellongowski P, Darmon M, Bauer PR, Benoit D, Depuydt P, et al. The Intensive Care Medicine research agenda on critically ill oncology and hematology patients. INTENSIVE CARE MEDICINE. 2017;43(9):1366–82.
IEEE
[1]
E. Azoulay et al., “The Intensive Care Medicine research agenda on critically ill oncology and hematology patients,” INTENSIVE CARE MEDICINE, vol. 43, no. 9, pp. 1366–1382, 2017.
@article{8551886,
  abstract     = {Over the coming years, accelerating progress against cancer will be associated with an increased number of patients who require life-sustaining therapies for infectious or toxic chemotherapy-related events. Major changes include increased number of cancer patients admitted to the ICU with full-code status or for time-limited trials, increased survival and quality of life in ICU survivors, changing prognostic factors, early ICU admission for optimal monitoring, and use of noninvasive diagnostic and therapeutic strategies. In this review, experts in the management of critically ill cancer patients highlight recent changes in the use and the results of intensive care in patients with malignancies. They seek to put forward a standard of care for the management of these patients and highlight important updates that are required to care for them. The research agenda they suggest includes important studies to be conducted in the next few years to increase our understanding of organ dysfunction in this population and to improve our ability to appropriately use life-saving therapies or select new therapeutic approaches that are likely to improve outcomes. This review aims to provide more guidance for the daily management of patients with cancer, in whom outcomes are constantly improving, as is our global ability to fight against what is becoming the leading cause of mortality in industrialized and non-industrialized countries.},
  author       = {Azoulay, Elie and Schellongowski, Peter and Darmon, Michael and Bauer, Philippe R and Benoit, Dominique and Depuydt, Pieter and Divatia, Jigeeshu V and Lemiale, Virginie and van Vliet, Maarten and Meert, Anne-Pascale and Mokart, Djamel and Pastores, Stephen M and Perner, Anders and Pène, Frédéric and Pickkers, Peter and Puxty, Kathryn A and Vincent, Francois and Salluh, Jorge and Soubani, Ayman O and Antonelli, Massimo and Staudinger, Thomas and von Bergwelt-Baildon, Michael and Soares, Marcio},
  issn         = {0342-4642},
  journal      = {INTENSIVE CARE MEDICINE},
  keywords     = {Neutropenia,Bone marrow transplantation,Mechanical ventilation,Oxygen,Acute respiratory failure,Septic shock,Cancer,Bronchoscopy,ACUTE RESPIRATORY-FAILURE,ACUTE LUNG INJURY,STEM-CELL TRANSPLANTATION,INFECTIOUS-DISEASES SOCIETY,RANDOMIZED-CONTROLLED-TRIAL,COLONY-STIMULATING FACTOR,RAPID RESPONSE SYSTEMS,ACUTE MYELOID-LEUKEMIA,ACUTE KIDNEY INJURY,LONG-TERM SURVIVAL},
  language     = {eng},
  number       = {9},
  pages        = {1366--1382},
  title        = {The Intensive Care Medicine research agenda on critically ill oncology and hematology patients},
  url          = {http://dx.doi.org/10.1007/s00134-017-4884-z},
  volume       = {43},
  year         = {2017},
}

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