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Gonadal dysgenesis in disorders of sex development : diagnosis and surgical management

(2016) JOURNAL OF PEDIATRIC UROLOGY. 12(6). p.411-416
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Abstract
Recent studies on gonadal histology have improved the understanding of germ cell malignancy risk in patients with disorders of sex development (DSD), and evidence-based gonadal management strategies are gradually emerging. Especially in 46, XY DSD and 45, X/46, XY DSD, which are characterized by gonadal dysgenesis, the risk of germ cell malignancy is significantly increased. This paper summarized the progress over the past 10 years in malignancy risk assessment in patients with DSD, and its implications for optimal surgical handling of the involved gonads.
Keywords
Gonadal dysgenesis (GD), Malignant germ cell tumors, Germ cell cancer (GCC), Disorders of sex development (DSD), Surgical management, ANDROGEN INSENSITIVITY SYNDROME, GERM-CELL NEOPLASIA, CARCINOMA IN-SITU, GONADOBLASTOMA, EXPRESSION, TUMORS, WOMEN, GENE

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Chicago
Wolffenbuttel, KP, R Hersmus, H Stoop, K Biermann, Piet Hoebeke, Martine Cools, and LHJ Looijenga. 2016. “Gonadal Dysgenesis in Disorders of Sex Development : Diagnosis and Surgical Management.” Journal of Pediatric Urology 12 (6): 411–416.
APA
Wolffenbuttel, K., Hersmus, R., Stoop, H., Biermann, K., Hoebeke, P., Cools, M., & Looijenga, L. (2016). Gonadal dysgenesis in disorders of sex development : diagnosis and surgical management. JOURNAL OF PEDIATRIC UROLOGY, 12(6), 411–416. Presented at the 26th Congress of the European Society of Paediatric Urology (ESPU 2015).
Vancouver
1.
Wolffenbuttel K, Hersmus R, Stoop H, Biermann K, Hoebeke P, Cools M, et al. Gonadal dysgenesis in disorders of sex development : diagnosis and surgical management. JOURNAL OF PEDIATRIC UROLOGY. 2016;12(6):411–6.
MLA
Wolffenbuttel, KP, R Hersmus, H Stoop, et al. “Gonadal Dysgenesis in Disorders of Sex Development : Diagnosis and Surgical Management.” JOURNAL OF PEDIATRIC UROLOGY 12.6 (2016): 411–416. Print.
@article{8550166,
  abstract     = {Recent studies on gonadal histology have improved the understanding of germ cell malignancy risk in patients with disorders of sex development (DSD), and evidence-based gonadal management strategies are gradually emerging. Especially in 46, XY DSD and 45, X/46, XY DSD, which are characterized by gonadal dysgenesis, the risk of germ cell malignancy is significantly increased. This paper summarized the progress over the past 10 years in malignancy risk assessment in patients with DSD, and its implications for optimal surgical handling of the involved gonads.},
  author       = {Wolffenbuttel, KP and Hersmus, R and Stoop, H and Biermann, K and Hoebeke, Piet and Cools, Martine and Looijenga, LHJ},
  issn         = {1477-5131},
  journal      = {JOURNAL OF PEDIATRIC UROLOGY},
  keyword      = {Gonadal dysgenesis (GD),Malignant germ cell tumors,Germ cell cancer (GCC),Disorders of sex development (DSD),Surgical management,ANDROGEN INSENSITIVITY SYNDROME,GERM-CELL NEOPLASIA,CARCINOMA IN-SITU,GONADOBLASTOMA,EXPRESSION,TUMORS,WOMEN,GENE},
  language     = {eng},
  location     = {Prague, Czech Republic},
  number       = {6},
  pages        = {411--416},
  title        = {Gonadal dysgenesis in disorders of sex development : diagnosis and surgical management},
  url          = {http://dx.doi.org/10.1016/j.jpurol.2016.08.015},
  volume       = {12},
  year         = {2016},
}

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