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Factors associated with health-related quality of life in stable ambulatory congestive heart failure patients : systematic review

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Abstract
Background: Since improved treatment of congestive heart failure has resulted in decreased mortality and hospitalisation rates, increasing self-perceived health-related quality of life (HRQoL) has become a major goal of congestive heart failure treatment. However, an overview on predictieve factors of HRQoL is currently lacking in literature. Purpose: The aim of this study was to identify key factors associated with HRQoL in stable ambulatory patients with congestive heart failure. Methods: A systematic review was performed. MEDLINE, Web of Science and Embase were searched for the following combination of terms: heart failure, quality of life, health perception or functional status between the period 2000 and February 2017. Literature screening was done by two independent reviewers. Results: Thirty-five studies out of 8374 titles were included for quality appraisal, of which 29 were selected for further data extraction. Four distinct categories grouping different types of variables were identified: socio-demographic characteristics, clinical characteristics, health and health behaviour, and care provider characteristics. Within the above-mentioned categories the presence of depressive symptoms was most consistently related to a worse HRQoL, followed by a higher New York Heart Association functional class, younger age and female gender. Conclusion: Through a systematic literature search, factors associated with HRQoL among congestive heart failure patients were investigated. Age, gender, New York Heart Association functional class and depressive symptoms are the most consistent variables explaining the variance in HRQoL in patients with congestive heart failure. These findings are partly in line with previous research on predictors for hard endpoints in patients with congestive heart failure.
Keywords
Quality of life, heart failure, systematic review, predictive factors, DEPRESSIVE SYMPTOMS, EUROPEAN-SOCIETY, IRON-DEFICIENCY, DIAGNOSIS, DISEASE, EPIDEMIOLOGY, PERSONALITY, GUIDELINES, MORTALITY, VARIABLES

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Chicago
Baert, Anneleen, Delphine De Smedt, Johan De Sutter, Dirk De Bacquer, Paolo Emilio Puddu, Els Clays, and Sofie Pardaens. 2018. “Factors Associated with Health-related Quality of Life in Stable Ambulatory Congestive Heart Failure Patients : Systematic Review.” European Journal of Preventive Cardiology 25 (5): 472–481.
APA
Baert, Anneleen, De Smedt, D., De Sutter, J., De Bacquer, D., Puddu, P. E., Clays, E., & Pardaens, S. (2018). Factors associated with health-related quality of life in stable ambulatory congestive heart failure patients : systematic review. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 25(5), 472–481.
Vancouver
1.
Baert A, De Smedt D, De Sutter J, De Bacquer D, Puddu PE, Clays E, et al. Factors associated with health-related quality of life in stable ambulatory congestive heart failure patients : systematic review. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2018;25(5):472–81.
MLA
Baert, Anneleen, Delphine De Smedt, Johan De Sutter, et al. “Factors Associated with Health-related Quality of Life in Stable Ambulatory Congestive Heart Failure Patients : Systematic Review.” EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY 25.5 (2018): 472–481. Print.
@article{8550018,
  abstract     = {Background: Since improved treatment of congestive heart failure has resulted in decreased mortality and hospitalisation rates, increasing self-perceived health-related quality of life (HRQoL) has become a major goal of congestive heart failure treatment. However, an overview on predictieve factors of HRQoL is currently lacking in literature. 
Purpose: The aim of this study was to identify key factors associated with HRQoL in stable ambulatory patients with congestive heart failure. 
Methods: A systematic review was performed. MEDLINE, Web of Science and Embase were searched for the following combination of terms: heart failure, quality of life, health perception or functional status between the period 2000 and February 2017. Literature screening was done by two independent reviewers. 
Results: Thirty-five studies out of 8374 titles were included for quality appraisal, of which 29 were selected for further data extraction. Four distinct categories grouping different types of variables were identified: socio-demographic characteristics, clinical characteristics, health and health behaviour, and care provider characteristics. Within the above-mentioned categories the presence of depressive symptoms was most consistently related to a worse HRQoL, followed by a higher New York Heart Association functional class, younger age and female gender. 
Conclusion: Through a systematic literature search, factors associated with HRQoL among congestive heart failure patients were investigated. Age, gender, New York Heart Association functional class and depressive symptoms are the most consistent variables explaining the variance in HRQoL in patients with congestive heart failure. These findings are partly in line with previous research on predictors for hard endpoints in patients with congestive heart failure.},
  author       = {Baert, Anneleen and De Smedt, Delphine and De Sutter, Johan and De Bacquer, Dirk and Puddu, Paolo Emilio and Clays, Els and Pardaens, Sofie},
  issn         = {2047-4873},
  journal      = {EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY},
  keyword      = {Quality of life,heart failure,systematic review,predictive factors,DEPRESSIVE SYMPTOMS,EUROPEAN-SOCIETY,IRON-DEFICIENCY,DIAGNOSIS,DISEASE,EPIDEMIOLOGY,PERSONALITY,GUIDELINES,MORTALITY,VARIABLES},
  language     = {eng},
  number       = {5},
  pages        = {472--481},
  title        = {Factors associated with health-related quality of life in stable ambulatory congestive heart failure patients : systematic review},
  url          = {http://dx.doi.org/10.1177/2047487318755795},
  volume       = {25},
  year         = {2018},
}

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