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This paper presents the latest state of art and developments in the quest for completing the challenging control of anesthesia, i.e the missing part of regulating analgesia. Drug rate to effect modelling and closed loop control of hypnosis and neuromuscular blockade seem to have been well characterized and successful in clinical practice. By contrast, analgesia remains an intricate process with multiple physiological stages at multiple scales in time and in body loci. Latest developments with fractional order kinetics and fractional order impedance models rise hope to the horizons yet to come. A perspective forms on the next steps to be tackled to achieve the complete guided control paradigm.
Keywords
SELF-ORGANIZING FUZZY, INTENSIVE-CARE-UNIT, FRACTIONAL CALCULUS, PROPOFOL ANESTHESIA, KINETICS, SEDATION, DEPTH

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Citation

Please use this url to cite or link to this publication:

MLA
Ionescu, Clara, and Dana Copot. “Guided Closed Loop Control of Analgesia : Are We There Yet?” 2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES), 2017, pp. 137–42.
APA
Ionescu, C., & Copot, D. (2017). Guided closed loop control of analgesia : are we there yet? 2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES), 137–142.
Chicago author-date
Ionescu, Clara, and Dana Copot. 2017. “Guided Closed Loop Control of Analgesia : Are We There Yet?” In 2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES), 137–42.
Chicago author-date (all authors)
Ionescu, Clara, and Dana Copot. 2017. “Guided Closed Loop Control of Analgesia : Are We There Yet?” In 2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES), 137–142.
Vancouver
1.
Ionescu C, Copot D. Guided closed loop control of analgesia : are we there yet? In: 2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES). 2017. p. 137–42.
IEEE
[1]
C. Ionescu and D. Copot, “Guided closed loop control of analgesia : are we there yet?,” in 2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES), Larnaca, CYPRUS, 2017, pp. 137–142.
@inproceedings{8544424,
  abstract     = {{This paper presents the latest state of art and developments in the quest for completing the challenging control of anesthesia, i.e the missing part of regulating analgesia. Drug rate to effect modelling and closed loop control of hypnosis and neuromuscular blockade seem to have been well characterized and successful in clinical practice. By contrast, analgesia remains an intricate process with multiple physiological stages at multiple scales in time and in body loci. Latest developments with fractional order kinetics and fractional order impedance models rise hope to the horizons yet to come. A perspective forms on the next steps to be tackled to achieve the complete guided control paradigm.}},
  author       = {{Ionescu, Clara and Copot, Dana}},
  booktitle    = {{2017 IEEE 21ST INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS (INES)}},
  isbn         = {{978-1-4799-7677-5}},
  issn         = {{1562-5850}},
  keywords     = {{SELF-ORGANIZING FUZZY,INTENSIVE-CARE-UNIT,FRACTIONAL CALCULUS,PROPOFOL ANESTHESIA,KINETICS,SEDATION,DEPTH}},
  language     = {{eng}},
  location     = {{Larnaca, CYPRUS}},
  pages        = {{137--142}},
  title        = {{Guided closed loop control of analgesia : are we there yet?}},
  year         = {{2017}},
}

Web of Science
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