Gut microbiota dysbiosis in postweaning piglets : understanding the keys to health
- Author
- Raphaele Gresse, Frederique Chaucheyras-Durand, Mickael Alain Fleury, Tom Van de Wiele (UGent) , Evelyne Forano and Stephanie Blanquet-Diot
- Organization
- Abstract
- Weaning is a critical event in the pig's life cycle, frequently associated with severe enteric infections and overuse of antibiotics; this raises serious economic and public health concerns. In this review, we explain why gut micro-biota dysbiosis, induced by abrupt changes in the diet and environment of piglets, emerges as a leading cause of post-weaning diarrhea, even if the exact underlying mechanisms remain unclear. Then, we focus on nonantimi-crobial alternatives, such as zinc oxide, essential oils, and prebiotics or probiotics, which are currently evaluated to restore intestinal balance and allow a better management of the crucial weaning transition. Finally, we discuss how in vitro models of the piglet gut could be advantageously used as a complement to ex vivo and in vivo studies for the development and testing of new feed additives.
- Keywords
- ENTEROTOXIGENIC ESCHERICHIA-COLI, NEWLY WEANED PIGLETS, DIETARY ZINC-OXIDE, IN-VITRO MODEL, ORGANIC-ACIDS, WEANING PIGS, GASTROINTESTINAL-TRACT, INTESTINAL MICROBIOTA, FEED SUPPLEMENTATION, BACTERIAL DIVERSITY
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8542573
- MLA
- Gresse, Raphaele, et al. “Gut Microbiota Dysbiosis in Postweaning Piglets : Understanding the Keys to Health.” TRENDS IN MICROBIOLOGY, vol. 25, no. 10, 2017, pp. 851–73, doi:10.1016/j.tim.2017.05.004.
- APA
- Gresse, R., Chaucheyras-Durand, F., Fleury, M. A., Van de Wiele, T., Forano, E., & Blanquet-Diot, S. (2017). Gut microbiota dysbiosis in postweaning piglets : understanding the keys to health. TRENDS IN MICROBIOLOGY, 25(10), 851–873. https://doi.org/10.1016/j.tim.2017.05.004
- Chicago author-date
- Gresse, Raphaele, Frederique Chaucheyras-Durand, Mickael Alain Fleury, Tom Van de Wiele, Evelyne Forano, and Stephanie Blanquet-Diot. 2017. “Gut Microbiota Dysbiosis in Postweaning Piglets : Understanding the Keys to Health.” TRENDS IN MICROBIOLOGY 25 (10): 851–73. https://doi.org/10.1016/j.tim.2017.05.004.
- Chicago author-date (all authors)
- Gresse, Raphaele, Frederique Chaucheyras-Durand, Mickael Alain Fleury, Tom Van de Wiele, Evelyne Forano, and Stephanie Blanquet-Diot. 2017. “Gut Microbiota Dysbiosis in Postweaning Piglets : Understanding the Keys to Health.” TRENDS IN MICROBIOLOGY 25 (10): 851–873. doi:10.1016/j.tim.2017.05.004.
- Vancouver
- 1.Gresse R, Chaucheyras-Durand F, Fleury MA, Van de Wiele T, Forano E, Blanquet-Diot S. Gut microbiota dysbiosis in postweaning piglets : understanding the keys to health. TRENDS IN MICROBIOLOGY. 2017;25(10):851–73.
- IEEE
- [1]R. Gresse, F. Chaucheyras-Durand, M. A. Fleury, T. Van de Wiele, E. Forano, and S. Blanquet-Diot, “Gut microbiota dysbiosis in postweaning piglets : understanding the keys to health,” TRENDS IN MICROBIOLOGY, vol. 25, no. 10, pp. 851–873, 2017.
@article{8542573, abstract = {{Weaning is a critical event in the pig's life cycle, frequently associated with severe enteric infections and overuse of antibiotics; this raises serious economic and public health concerns. In this review, we explain why gut micro-biota dysbiosis, induced by abrupt changes in the diet and environment of piglets, emerges as a leading cause of post-weaning diarrhea, even if the exact underlying mechanisms remain unclear. Then, we focus on nonantimi-crobial alternatives, such as zinc oxide, essential oils, and prebiotics or probiotics, which are currently evaluated to restore intestinal balance and allow a better management of the crucial weaning transition. Finally, we discuss how in vitro models of the piglet gut could be advantageously used as a complement to ex vivo and in vivo studies for the development and testing of new feed additives.}}, author = {{Gresse, Raphaele and Chaucheyras-Durand, Frederique and Fleury, Mickael Alain and Van de Wiele, Tom and Forano, Evelyne and Blanquet-Diot, Stephanie}}, issn = {{0966-842X}}, journal = {{TRENDS IN MICROBIOLOGY}}, keywords = {{ENTEROTOXIGENIC ESCHERICHIA-COLI,NEWLY WEANED PIGLETS,DIETARY ZINC-OXIDE,IN-VITRO MODEL,ORGANIC-ACIDS,WEANING PIGS,GASTROINTESTINAL-TRACT,INTESTINAL MICROBIOTA,FEED SUPPLEMENTATION,BACTERIAL DIVERSITY}}, language = {{eng}}, number = {{10}}, pages = {{851--873}}, title = {{Gut microbiota dysbiosis in postweaning piglets : understanding the keys to health}}, url = {{http://doi.org/10.1016/j.tim.2017.05.004}}, volume = {{25}}, year = {{2017}}, }
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