Advanced search
1 file | 1.11 MB

Role of mycotoxins in herds with and without problems with tail necrosis in neonatal pigs

Tommy Van Limbergen (UGent) , Mathias Devreese (UGent) , Siska Croubels (UGent) , Nathan Broekaert (UGent) , Annelies Michiels (UGent) , Sarah De Saeger (UGent) and Dominiek Maes (UGent)
(2017) VETERINARY RECORD. 181(20).
Author
Organization
Abstract
This study aimed to investigate a possible involvement of mycotoxins in neonatal tail necrosis in piglets. Ten affected and 10 non-affected farms were selected. Sow feed samples were analysed for the presence of 23 mycotoxins by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Blood plasma samples of sows and their piglets were analysed for the presence of deoxynivalenol (DON), de-epoxydeoxynivalenol, T-2 and HT-2 toxin, zearalenone, alfa-zearalenol, and beta-zearalenol, using LC-MS/MS. Additionally, high-resolution mass spectrometry (HRMS) was performed to detect DON-glucuronide (DON-Glca). There was a significant difference between case herds and control herds for mean DON concentrations in feed and sow plasma. For piglet samples, concentrations of DON were above the limit of quantification of 0.1 ng/ml in only 12 samples. Positive correlations were found between DON concentrations in sow feed and plasma of sows; DON concentration in sow feed and DON-Glca concentration in plasma of sows; and between DON and DON-Glca concentration in sow-plasma. In conclusion, high prevalence of DON in feed samples was found, with significantly higher concentrations in case herds, as well as the presence of DON and DON-Glca in sow plasma. Additional research is needed to identify risk factors, including within-herd factors, associated with neonatal tail necrosis in piglets.
Keywords
LC-MS/MS METHOD, DEOXYNIVALENOL DON, PIGLET SURVIVAL, ANIMAL HEALTH, ACETYLATED DERIVATIVES, FUSARIUM MYCOTOXINS, MULTI-MYCOTOXIN, GROWING PIGS, WHEAT, PERFORMANCE

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 1.11 MB

Citation

Please use this url to cite or link to this publication:

Chicago
Van Limbergen, Tommy, Mathias Devreese, Siska Croubels, Nathan Broekaert, Annelies Michiels, Sarah De Saeger, and Dominiek Maes. 2017. “Role of Mycotoxins in Herds with and Without Problems with Tail Necrosis in Neonatal Pigs.” Veterinary Record 181 (20).
APA
Van Limbergen, T., Devreese, M., Croubels, S., Broekaert, N., Michiels, A., De Saeger, S., & Maes, D. (2017). Role of mycotoxins in herds with and without problems with tail necrosis in neonatal pigs. VETERINARY RECORD, 181(20).
Vancouver
1.
Van Limbergen T, Devreese M, Croubels S, Broekaert N, Michiels A, De Saeger S, et al. Role of mycotoxins in herds with and without problems with tail necrosis in neonatal pigs. VETERINARY RECORD. 2017;181(20).
MLA
Van Limbergen, Tommy et al. “Role of Mycotoxins in Herds with and Without Problems with Tail Necrosis in Neonatal Pigs.” VETERINARY RECORD 181.20 (2017): n. pag. Print.
@article{8542450,
  abstract     = {This study aimed to investigate a possible involvement of mycotoxins in neonatal tail necrosis in piglets. Ten affected and 10 non-affected farms were selected. Sow feed samples were analysed for the presence of 23 mycotoxins by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Blood plasma samples of sows and their piglets were analysed for the presence of deoxynivalenol (DON), de-epoxydeoxynivalenol, T-2 and HT-2 toxin, zearalenone, alfa-zearalenol, and beta-zearalenol, using LC-MS/MS. Additionally, high-resolution mass spectrometry (HRMS) was performed to detect DON-glucuronide (DON-Glca). There was a significant difference between case herds and control herds for mean DON concentrations in feed and sow plasma. For piglet samples, concentrations of DON were above the limit of quantification of 0.1 ng/ml in only 12 samples. Positive correlations were found between DON concentrations in sow feed and plasma of sows; DON concentration in sow feed and DON-Glca concentration in plasma of sows; and between DON and DON-Glca concentration in sow-plasma. In conclusion, high prevalence of DON in feed samples was found, with significantly higher concentrations in case herds, as well as the presence of DON and DON-Glca in sow plasma. Additional research is needed to identify risk factors, including within-herd factors, associated with neonatal tail necrosis in piglets.},
  articleno    = {539},
  author       = {Van Limbergen, Tommy and Devreese, Mathias and Croubels, Siska and Broekaert, Nathan and Michiels, Annelies and De Saeger, Sarah and Maes, Dominiek},
  issn         = {0042-4900},
  journal      = {VETERINARY RECORD},
  keywords     = {LC-MS/MS METHOD,DEOXYNIVALENOL DON,PIGLET SURVIVAL,ANIMAL HEALTH,ACETYLATED DERIVATIVES,FUSARIUM MYCOTOXINS,MULTI-MYCOTOXIN,GROWING PIGS,WHEAT,PERFORMANCE},
  language     = {eng},
  number       = {20},
  pages        = {9},
  title        = {Role of mycotoxins in herds with and without problems with tail necrosis in neonatal pigs},
  url          = {http://dx.doi.org/10.1136/vr.104385},
  volume       = {181},
  year         = {2017},
}

Altmetric
View in Altmetric
Web of Science
Times cited: