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How do we fit ferroptosis in the family of regulated cell death?

(2017) CELL DEATH AND DIFFERENTIATION. 24(12). p.1991-1998
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Abstract
In the last few years many new cell death modalities have been described. To classify different types of cell death, the term 'regulated cell death' was introduced to discriminate it from 'accidental cell death'. Regulated cell death involves the activation of genetically encoded molecular machinery that couples the presence of some signal to cell death. These forms of cell death, like apoptosis, necroptosis and pyroptosis have important physiological roles in development, tissue repair, and immunity. Accidental cell death occurs in response to physical or chemical insults and occurs independently of molecular signalling pathways. Ferroptosis, an emerging and recently (re) discovered type of regulated cell death occurs through Fe(II)-dependent lipid peroxidation when the reduction capacity of a cell is insufficient. Ferroptosis is coined after the requirement for free ferrous iron. Here, we will consider the extent to which ferroptosis is similar to other regulated cell deaths and explore emerging ideas about the physiological role of ferroptosis.
Keywords
INDUCED LIPID-PEROXIDATION, DIETARY ALPHA-TOCOPHEROL, METHYL, MERCURIC-CHLORIDE, INNATE IMMUNE DETECTION, III SECRETION SYSTEM, OXIDATIVE STRESS, VITAMIN-E, TUMOR SUPPRESSION, MEDIATES NECROPTOSIS, CARBON-TETRACHLORIDE

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Citation

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Chicago
Fearnhead, Howard O, Peter Vandenabeele, and Tom Vanden Berghe. 2017. “How Do We Fit Ferroptosis in the Family of Regulated Cell Death?” Cell Death and Differentiation 24 (12): 1991–1998.
APA
Fearnhead, H. O., Vandenabeele, P., & Vanden Berghe, T. (2017). How do we fit ferroptosis in the family of regulated cell death? CELL DEATH AND DIFFERENTIATION, 24(12), 1991–1998.
Vancouver
1.
Fearnhead HO, Vandenabeele P, Vanden Berghe T. How do we fit ferroptosis in the family of regulated cell death? CELL DEATH AND DIFFERENTIATION. 2017;24(12):1991–8.
MLA
Fearnhead, Howard O, Peter Vandenabeele, and Tom Vanden Berghe. “How Do We Fit Ferroptosis in the Family of Regulated Cell Death?” CELL DEATH AND DIFFERENTIATION 24.12 (2017): 1991–1998. Print.
@article{8540614,
  abstract     = {In the last few years many new cell death modalities have been described. To classify different types of cell death, the term 'regulated cell death' was introduced to discriminate it from 'accidental cell death'. Regulated cell death involves the activation of genetically encoded molecular machinery that couples the presence of some signal to cell death. These forms of cell death, like apoptosis, necroptosis and pyroptosis have important physiological roles in development, tissue repair, and immunity. Accidental cell death occurs in response to physical or chemical insults and occurs independently of molecular signalling pathways. Ferroptosis, an emerging and recently (re) discovered type of regulated cell death occurs through Fe(II)-dependent lipid peroxidation when the reduction capacity of a cell is insufficient. Ferroptosis is coined after the requirement for free ferrous iron. Here, we will consider the extent to which ferroptosis is similar to other regulated cell deaths and explore emerging ideas about the physiological role of ferroptosis.},
  author       = {Fearnhead, Howard O and Vandenabeele, Peter and Vanden Berghe, Tom},
  issn         = {1350-9047},
  journal      = {CELL DEATH AND DIFFERENTIATION},
  keyword      = {INDUCED LIPID-PEROXIDATION,DIETARY ALPHA-TOCOPHEROL,METHYL,MERCURIC-CHLORIDE,INNATE IMMUNE DETECTION,III SECRETION SYSTEM,OXIDATIVE STRESS,VITAMIN-E,TUMOR SUPPRESSION,MEDIATES NECROPTOSIS,CARBON-TETRACHLORIDE},
  language     = {eng},
  number       = {12},
  pages        = {1991--1998},
  title        = {How do we fit ferroptosis in the family of regulated cell death?},
  url          = {http://dx.doi.org/10.1038/cdd.2017.149},
  volume       = {24},
  year         = {2017},
}

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