Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries
- Author
- Evelien Van Rymenant, Charlotte Grootaert (UGent) , Katrijn Beerens, PW Needs, PA Kroon, A Kerimi, G Williamson, R García-Villalba, A González-Sarrías, F Tomas-Barberan, John Van Camp (UGent) and Johan Van de Voorde (UGent)
- Organization
- Abstract
- Polyphenols are beneficial for health{,} but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin{,} urolithins and ferulic acid-4-O-sulfate - not their glucuronidated forms or ferulic acid - caused vasorelaxation. Therefore{,} we advise the use of relevant conjugates in future mechanistic research.
- Keywords
- ENDOTHELIUM-DEPENDENT VASODILATION, SPONTANEOUSLY HYPERTENSIVE-RATS, FERULIC ACID, ELLAGIC ACID, PROTOCATECHUIC ACID, BIOLOGICAL-ACTIVITY, HEALTHY HUMANS, BLOOD-PRESSURE, GLUCURONIDES, POLYPHENOLS
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8538572
- MLA
- Van Rymenant, Evelien, et al. “Vasorelaxant Activity of Twenty-One Physiologically Relevant (Poly)Phenolic Metabolites on Isolated Mouse Arteries.” FOOD & FUNCTION, vol. 8, no. 12, 2018, pp. 4331–35, doi:10.1039/C7FO01273J.
- APA
- Van Rymenant, E., Grootaert, C., Beerens, K., Needs, P., Kroon, P., Kerimi, A., … Van de Voorde, J. (2018). Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries. FOOD & FUNCTION, 8(12), 4331–4335. https://doi.org/10.1039/C7FO01273J
- Chicago author-date
- Van Rymenant, Evelien, Charlotte Grootaert, Katrijn Beerens, PW Needs, PA Kroon, A Kerimi, G Williamson, et al. 2018. “Vasorelaxant Activity of Twenty-One Physiologically Relevant (Poly)Phenolic Metabolites on Isolated Mouse Arteries.” FOOD & FUNCTION 8 (12): 4331–35. https://doi.org/10.1039/C7FO01273J.
- Chicago author-date (all authors)
- Van Rymenant, Evelien, Charlotte Grootaert, Katrijn Beerens, PW Needs, PA Kroon, A Kerimi, G Williamson, R García-Villalba, A González-Sarrías, F Tomas-Barberan, John Van Camp, and Johan Van de Voorde. 2018. “Vasorelaxant Activity of Twenty-One Physiologically Relevant (Poly)Phenolic Metabolites on Isolated Mouse Arteries.” FOOD & FUNCTION 8 (12): 4331–4335. doi:10.1039/C7FO01273J.
- Vancouver
- 1.Van Rymenant E, Grootaert C, Beerens K, Needs P, Kroon P, Kerimi A, et al. Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries. FOOD & FUNCTION. 2018;8(12):4331–5.
- IEEE
- [1]E. Van Rymenant et al., “Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries,” FOOD & FUNCTION, vol. 8, no. 12, pp. 4331–4335, 2018.
@article{8538572,
abstract = {{Polyphenols are beneficial for health{,} but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin{,} urolithins and ferulic acid-4-O-sulfate - not their glucuronidated forms or ferulic acid - caused vasorelaxation. Therefore{,} we advise the use of relevant conjugates in future mechanistic research.}},
author = {{Van Rymenant, Evelien and Grootaert, Charlotte and Beerens, Katrijn and Needs, PW and Kroon, PA and Kerimi, A and Williamson, G and García-Villalba, R and González-Sarrías, A and Tomas-Barberan, F and Van Camp, John and Van de Voorde, Johan}},
issn = {{2042-6496}},
journal = {{FOOD & FUNCTION}},
keywords = {{ENDOTHELIUM-DEPENDENT VASODILATION,SPONTANEOUSLY HYPERTENSIVE-RATS,FERULIC ACID,ELLAGIC ACID,PROTOCATECHUIC ACID,BIOLOGICAL-ACTIVITY,HEALTHY HUMANS,BLOOD-PRESSURE,GLUCURONIDES,POLYPHENOLS}},
language = {{eng}},
number = {{12}},
pages = {{4331--4335}},
title = {{Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries}},
url = {{http://doi.org/10.1039/C7FO01273J}},
volume = {{8}},
year = {{2018}},
}
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