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Chronic fatigue syndrome : an update

Steven Rimbaut (UGent) , Céline Van Gutte (UGent) , Lina Van Brabander (UGent) and Luc Vanden Bossche (UGent)
(2016) ACTA CLINICA BELGICA. 71(5). p.273-280
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Abstract
Background: Chronic fatigue syndrome is a widespread condition with a huge impact not only on a patient's life, but also on society as evidenced by substantial losses of productivity, informal costs, and medical expenses. The high prevalence rates (0.2-6.4%) and the low employment rates (27-41%) are responsible for the enormous burden imposed on society, with loss of productivity representing the highest cost. The objective of this review is to systematically review the recent literature on chronic fatigue syndrome/myalgic encephalomyelitis. Methods: The published literature between 1 January 1990 and 1 April 2015 was searched using the MEDLINE, Cochrane Library, and Web of Sciences databases. The reference lists of the selected articles were screened for other relevant articles. Results and conclusions: Despite extensive research, none of the proposed etiological factors have shown strong, reproducible scientific evidence. Over the years, the biopsychosocial model integrating many of the proposed hypotheses has been gaining popularity over the biomedical model, where the focus is on one physical cause. Since the etiological mechanism underlying chronic fatigue syndrome is currently unknown, disease-specific treatments do not exist. Various treatments have been investigated but only cognitive behavior therapy (CBT) and graded exercise therapy (GET) have shown moderate effectiveness.
Keywords
Chronic fatigue syndrome, Systematic review, Cost of care, Evidence based medicine, Exercise, activity, Physiotherapy, COGNITIVE-BEHAVIOR THERAPY, VIRAL-INFECTION, PRIMARY-CARE, BLOOD, PREVALENCE, POPULATION, SLEEP, ENCEPHALOMYELITIS, ABNORMALITIES, FIBROMYALGIA

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Citation

Please use this url to cite or link to this publication:

Chicago
Rimbaut, Steven, Céline Van Gutte, Lina Van Brabander, and Luc Vanden Bossche. 2016. “Chronic Fatigue Syndrome : an Update.” Acta Clinica Belgica 71 (5): 273–280.
APA
Rimbaut, S., Van Gutte, C., Van Brabander, L., & Vanden Bossche, L. (2016). Chronic fatigue syndrome : an update. ACTA CLINICA BELGICA, 71(5), 273–280.
Vancouver
1.
Rimbaut S, Van Gutte C, Van Brabander L, Vanden Bossche L. Chronic fatigue syndrome : an update. ACTA CLINICA BELGICA. 2016;71(5):273–80.
MLA
Rimbaut, Steven et al. “Chronic Fatigue Syndrome : an Update.” ACTA CLINICA BELGICA 71.5 (2016): 273–280. Print.
@article{8538060,
  abstract     = {Background: Chronic fatigue syndrome is a widespread condition with a huge impact not only on a patient's life, but also on society as evidenced by substantial losses of productivity, informal costs, and medical expenses. The high prevalence rates (0.2-6.4%) and the low employment rates (27-41%) are responsible for the enormous burden imposed on society, with loss of productivity representing the highest cost. The objective of this review is to systematically review the recent literature on chronic fatigue syndrome/myalgic encephalomyelitis.
Methods: The published literature between 1 January 1990 and 1 April 2015 was searched using the MEDLINE, Cochrane Library, and Web of Sciences databases. The reference lists of the selected articles were screened for other relevant articles.
Results and conclusions: Despite extensive research, none of the proposed etiological factors have shown strong, reproducible scientific evidence. Over the years, the biopsychosocial model integrating many of the proposed hypotheses has been gaining popularity over the biomedical model, where the focus is on one physical cause. Since the etiological mechanism underlying chronic fatigue syndrome is currently unknown, disease-specific treatments do not exist. Various treatments have been investigated but only cognitive behavior therapy (CBT) and graded exercise therapy (GET) have shown moderate effectiveness.},
  author       = {Rimbaut, Steven and Van Gutte, Céline and Van Brabander, Lina and Vanden Bossche, Luc},
  issn         = {1784-3286},
  journal      = {ACTA CLINICA BELGICA},
  keywords     = {Chronic fatigue syndrome,Systematic review,Cost of care,Evidence based medicine,Exercise,activity,Physiotherapy,COGNITIVE-BEHAVIOR THERAPY,VIRAL-INFECTION,PRIMARY-CARE,BLOOD,PREVALENCE,POPULATION,SLEEP,ENCEPHALOMYELITIS,ABNORMALITIES,FIBROMYALGIA},
  language     = {eng},
  number       = {5},
  pages        = {273--280},
  title        = {Chronic fatigue syndrome : an update},
  url          = {http://dx.doi.org/10.1080/17843286.2016.1196862},
  volume       = {71},
  year         = {2016},
}

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