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Proteins with an Euonymus lectin-like domain are ubiquitous in Embryophyta

Elke Fouquaert UGent, Willy J Peumans, Tom Vandekerckhove UGent, Maté Ongenaert UGent and Els Van Damme UGent (2009) BMC PLANT BIOLOGY. 9.
abstract
Background: Cloning of the Euonymus lectin led to the discovery of a novel domain that also occurs in some stress-induced plant proteins. The distribution and the diversity of proteins with an Euonymus lectin (EUL) domain were investigated using detailed analysis of sequences in publicly accessible genome and transcriptome databases. Results: Comprehensive in silico analyses indicate that the recently identified Euonymus europaeus lectin domain represents a conserved structural unit of a novel family of putative carbohydrate-binding proteins, which will further be referred to as the Euonymus lectin (EUL) family. The EUL domain is widespread among plants. Analysis of retrieved sequences revealed that some sequences consist of a single EUL domain linked to an unrelated N-terminal domain whereas others comprise two in tandem arrayed EUL domains. A new classification system for these lectins is proposed based on the overall domain architecture. Evolutionary relationships among the sequences with EUL domains are discussed. Conclusion: The identification of the EUL family provides the first evidence for the occurrence in terrestrial plants of a highly conserved plant specific domain. The widespread distribution of the EUL domain strikingly contrasts the more limited or even narrow distribution of most other lectin domains found in plants. The apparent omnipresence of the EUL domain is indicative for a universal role of this lectin domain in plants. Although there is unambiguous evidence that several EUL domains possess carbohydrate-binding activity further research is required to corroborate the carbohydrate-binding properties of different members of the EUL family.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
GLYCANS, FAMILY, STRESS, ABSCISIC-ACID, PLANT-LECTINS, PHYLOGENETIC TREES, PROTEOME, RESPONSES
journal title
BMC PLANT BIOLOGY
BMC Plant Biol.
volume
9
pages
17 pages
Web of Science type
Article
Web of Science id
000272449000002
JCR category
PLANT SCIENCES
JCR impact factor
3.774 (2009)
JCR rank
16/172 (2009)
JCR quartile
1 (2009)
ISSN
1471-2229
DOI
10.1186/1471-2229-9-136
language
English
UGent publication?
yes
classification
A1
additional info
article no. 136 (17 p.)
copyright statement
I have retained and own the full copyright for this publication
id
853715
handle
http://hdl.handle.net/1854/LU-853715
date created
2010-02-05 15:18:54
date last changed
2010-02-16 14:05:09
@article{853715,
  abstract     = {Background: Cloning of the Euonymus lectin led to the discovery of a novel domain that also occurs in some stress-induced plant proteins. The distribution and the diversity of proteins with an Euonymus lectin (EUL) domain were investigated using detailed analysis of sequences in publicly accessible genome and transcriptome databases.
Results: Comprehensive in silico analyses indicate that the recently identified Euonymus europaeus lectin domain represents a conserved structural unit of a novel family of putative carbohydrate-binding proteins, which will further be referred to as the Euonymus lectin (EUL) family. The EUL domain is widespread among plants. Analysis of retrieved sequences revealed that some sequences consist of a single EUL domain linked to an unrelated N-terminal domain whereas others comprise two in tandem arrayed EUL domains. A new classification system for these lectins is proposed based on the overall domain architecture. Evolutionary relationships among the sequences with EUL domains are discussed.
Conclusion: The identification of the EUL family provides the first evidence for the occurrence in terrestrial plants of a highly conserved plant specific domain. The widespread distribution of the EUL domain strikingly contrasts the more limited or even narrow distribution of most other lectin domains found in plants. The apparent omnipresence of the EUL domain is indicative for a universal role of this lectin domain in plants. Although there is unambiguous evidence that several EUL domains possess carbohydrate-binding activity further research is required to corroborate the carbohydrate-binding properties of different members of the EUL family.},
  author       = {Fouquaert, Elke and Peumans, Willy J and Vandekerckhove, Tom and Ongenaert, Mat{\'e} and Van Damme, Els},
  issn         = {1471-2229},
  journal      = {BMC PLANT BIOLOGY},
  keyword      = {GLYCANS,FAMILY,STRESS,ABSCISIC-ACID,PLANT-LECTINS,PHYLOGENETIC TREES,PROTEOME,RESPONSES},
  language     = {eng},
  pages        = {17},
  title        = {Proteins with an Euonymus lectin-like domain are ubiquitous in Embryophyta},
  url          = {http://dx.doi.org/10.1186/1471-2229-9-136},
  volume       = {9},
  year         = {2009},
}

Chicago
Fouquaert, Elke, Willy J Peumans, Tom Vandekerckhove, Maté Ongenaert, and Els Van Damme. 2009. “Proteins with an Euonymus Lectin-like Domain Are Ubiquitous in Embryophyta.” Bmc Plant Biology 9.
APA
Fouquaert, E., Peumans, W. J., Vandekerckhove, T., Ongenaert, M., & Van Damme, E. (2009). Proteins with an Euonymus lectin-like domain are ubiquitous in Embryophyta. BMC PLANT BIOLOGY, 9.
Vancouver
1.
Fouquaert E, Peumans WJ, Vandekerckhove T, Ongenaert M, Van Damme E. Proteins with an Euonymus lectin-like domain are ubiquitous in Embryophyta. BMC PLANT BIOLOGY. 2009;9.
MLA
Fouquaert, Elke, Willy J Peumans, Tom Vandekerckhove, et al. “Proteins with an Euonymus Lectin-like Domain Are Ubiquitous in Embryophyta.” BMC PLANT BIOLOGY 9 (2009): n. pag. Print.