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The intriguing role of soluble urokinase receptor in inflammatory diseases

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Abstract
Inflammation is a key player in the development of an increasing amount of diseases. The soluble urokinase plasminogen activator receptor (suPAR) is a highly flexible molecule with intrinsic chemotactic properties. This glycoprotein has been evaluated as a biomarker of inflammation, immune activation, organ damage and clinical outcome in several pathologies, including cardiovascular disease, hepatitis, renal disorders and rheumatic pathologies. The use of this early warning inflammatory biomarker could potentially improve the prediction of the severity of these diseases and mortality. In the present paper, we describe the general characteristics of suPAR and its intriguing role as a biomarker in different inflammatory diseases.
Keywords
PLASMINOGEN-ACTIVATOR RECEPTOR, FOCAL SEGMENTAL GLOMERULOSCLEROSIS, CRITICALLY-ILL PATIENTS, C-REACTIVE-PROTEIN, CORONARY-ARTERY-DISEASE, CHRONIC KIDNEY-DISEASE, INTENSIVE-CARE-UNIT, SERUM SUPAR LEVELS, CELL-ADHESION, CARDIOVASCULAR-DISEASE, Biomarker, chemotaxis, immune activation, inflammation, soluble, urokinase plasminogen activator receptor

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Chicago
Desmedt, Stéphanie, Valérie Desmedt, Joris Delanghe, Reinhart Speeckaert, and Marijn Speeckaert. 2017. “The Intriguing Role of Soluble Urokinase Receptor in Inflammatory Diseases.” Critical Reviews in Clinical Laboratory Sciences 54 (2): 117–133.
APA
Desmedt, S., Desmedt, V., Delanghe, J., Speeckaert, R., & Speeckaert, M. (2017). The intriguing role of soluble urokinase receptor in inflammatory diseases. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES, 54(2), 117–133.
Vancouver
1.
Desmedt S, Desmedt V, Delanghe J, Speeckaert R, Speeckaert M. The intriguing role of soluble urokinase receptor in inflammatory diseases. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES. 2017;54(2):117–33.
MLA
Desmedt, Stéphanie, Valérie Desmedt, Joris Delanghe, et al. “The Intriguing Role of Soluble Urokinase Receptor in Inflammatory Diseases.” CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES 54.2 (2017): 117–133. Print.
@article{8529593,
  abstract     = {Inflammation is a key player in the development of an increasing amount of diseases. The soluble urokinase plasminogen activator receptor (suPAR) is a highly flexible molecule with intrinsic chemotactic properties. This glycoprotein has been evaluated as a biomarker of inflammation, immune activation, organ damage and clinical outcome in several pathologies, including cardiovascular disease, hepatitis, renal disorders and rheumatic pathologies. The use of this early warning inflammatory biomarker could potentially improve the prediction of the severity of these diseases and mortality. In the present paper, we describe the general characteristics of suPAR and its intriguing role as a biomarker in different inflammatory diseases.},
  author       = {Desmedt, St{\'e}phanie and Desmedt, Val{\'e}rie and Delanghe, Joris and Speeckaert, Reinhart and Speeckaert, Marijn},
  issn         = {1040-8363},
  journal      = {CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES},
  keyword      = {PLASMINOGEN-ACTIVATOR RECEPTOR,FOCAL SEGMENTAL GLOMERULOSCLEROSIS,CRITICALLY-ILL PATIENTS,C-REACTIVE-PROTEIN,CORONARY-ARTERY-DISEASE,CHRONIC KIDNEY-DISEASE,INTENSIVE-CARE-UNIT,SERUM SUPAR LEVELS,CELL-ADHESION,CARDIOVASCULAR-DISEASE,Biomarker,chemotaxis,immune activation,inflammation,soluble,urokinase plasminogen activator receptor},
  language     = {eng},
  number       = {2},
  pages        = {117--133},
  title        = {The intriguing role of soluble urokinase receptor in inflammatory diseases},
  url          = {http://dx.doi.org/10.1080/10408363.2016.1269310},
  volume       = {54},
  year         = {2017},
}

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