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Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma

Julie Dutoit (UGent) and Koenraad Verstraete (UGent)
(2017) SKELETAL RADIOLOGY. 46(6). p.733-750
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Abstract
Magnetic resonance imaging (MRI) is the most sensitive imaging technique for the detection of bone marrow infiltration, and has therefore recently been included in the new diagnostic myeloma criteria, as proposed by the International Myeloma Working Group. Nevertheless, conventional MRI only provides anatomical information and is therefore only of limited use in the response assessment of patients with multiple myeloma. The additional information from functional MRI techniques, such as diffusion-weighted imaging and dynamic contrast-enhanced MRI, can improve the detection rate of bone marrow infiltration and the assessment of response. This can further enhance the sensitivity and specificity of MRI in the staging of multiple myeloma patients. This article provides an overview of the technical aspects of conventional and functional MRI techniques with practical recommendations. It reviews the diagnostic performance, prognostic value, and role in therapy assessment in multiple myeloma and its precursor stages.
Keywords
BONE-MARROW ANGIOGENESIS, POSITRON-EMISSION-TOMOGRAPHY, STEM-CELL, TRANSPLANTATION, MONOCLONAL GAMMOPATHY, PROGNOSTIC-SIGNIFICANCE, DCE-MRI, UNDETERMINED SIGNIFICANCE, TREATMENT RESPONSE, DISEASE-ACTIVITY, FOLLOW-UP, Multiple myeloma, MRI, Diffusion-weighted imaging, Dynamic, contrast-enhanced MRI

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Chicago
Dutoit, Julie, and Koenraad Verstraete. 2017. “Whole-body MRI, Dynamic Contrast-enhanced MRI, and Diffusion-weighted Imaging for the Staging of Multiple Myeloma.” Skeletal Radiology 46 (6): 733–750.
APA
Dutoit, J., & Verstraete, K. (2017). Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma. SKELETAL RADIOLOGY, 46(6), 733–750.
Vancouver
1.
Dutoit J, Verstraete K. Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma. SKELETAL RADIOLOGY. 2017;46(6):733–50.
MLA
Dutoit, Julie, and Koenraad Verstraete. “Whole-body MRI, Dynamic Contrast-enhanced MRI, and Diffusion-weighted Imaging for the Staging of Multiple Myeloma.” SKELETAL RADIOLOGY 46.6 (2017): 733–750. Print.
@article{8527655,
  abstract     = {Magnetic resonance imaging (MRI) is the most sensitive imaging technique for the detection of bone marrow infiltration, and has therefore recently been included in the new diagnostic myeloma criteria, as proposed by the International Myeloma Working Group. Nevertheless, conventional MRI only provides anatomical information and is therefore only of limited use in the response assessment of patients with multiple myeloma. The additional information from functional MRI techniques, such as diffusion-weighted imaging and dynamic contrast-enhanced MRI, can improve the detection rate of bone marrow infiltration and the assessment of response. This can further enhance the sensitivity and specificity of MRI in the staging of multiple myeloma patients. This article provides an overview of the technical aspects of conventional and functional MRI techniques with practical recommendations. It reviews the diagnostic performance, prognostic value, and role in therapy assessment in multiple myeloma and its precursor stages.},
  author       = {Dutoit, Julie and Verstraete, Koenraad},
  issn         = {0364-2348},
  journal      = {SKELETAL RADIOLOGY},
  keyword      = {BONE-MARROW ANGIOGENESIS,POSITRON-EMISSION-TOMOGRAPHY,STEM-CELL,TRANSPLANTATION,MONOCLONAL GAMMOPATHY,PROGNOSTIC-SIGNIFICANCE,DCE-MRI,UNDETERMINED SIGNIFICANCE,TREATMENT RESPONSE,DISEASE-ACTIVITY,FOLLOW-UP,Multiple myeloma,MRI,Diffusion-weighted imaging,Dynamic,contrast-enhanced MRI},
  language     = {eng},
  number       = {6},
  pages        = {733--750},
  title        = {Whole-body MRI, dynamic contrast-enhanced MRI, and diffusion-weighted imaging for the staging of multiple myeloma},
  url          = {http://dx.doi.org/10.1007/s00256-017-2609-6},
  volume       = {46},
  year         = {2017},
}

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