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Influenza and memory T cells : how to awake the force

Jan Spitaels (UGent) , Kenny Roose (UGent) and Xavier Saelens (UGent)
(2016) VACCINES. 4(4).
Author
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Abstract
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals. The past few years, the importance of cellular immunity, and especially memory T cells, in long-lived protection against influenza virus has become clear. To overcome the shortcomings of current influenza vaccines, eliciting both humoral and cellular immunity is imperative. Today, several new vaccines such as infection-permissive and recombinant T cell inducing vaccines, are being developed and show promising results. These vaccines will allow us to stay several steps ahead of the constantly evolving influenza virus.
Keywords
influenza, vaccines, cellular immunity, memory T cells, RESPIRATORY VIRUS-INFECTIONS, CELLULAR IMMUNE-RESPONSES, LUNG DENDRITIC CELLS, BRONCHIAL LYMPH-NODE, A VIRUS, CUTTING EDGE, ALVEOLAR MACROPHAGES, VIRAL-INFECTION, B VIRUSES, MEDIATED CYTOTOXICITY

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Citation

Please use this url to cite or link to this publication:

Chicago
Spitaels, Jan, Kenny Roose, and Xavier Saelens. 2016. “Influenza and Memory T Cells : How to Awake the Force.” Vaccines 4 (4).
APA
Spitaels, J., Roose, K., & Saelens, X. (2016). Influenza and memory T cells : how to awake the force. VACCINES, 4(4).
Vancouver
1.
Spitaels J, Roose K, Saelens X. Influenza and memory T cells : how to awake the force. VACCINES. 2016;4(4).
MLA
Spitaels, Jan, Kenny Roose, and Xavier Saelens. “Influenza and Memory T Cells : How to Awake the Force.” VACCINES 4.4 (2016): n. pag. Print.
@article{8525954,
  abstract     = {Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals. The past few years, the importance of cellular immunity, and especially memory T cells, in long-lived protection against influenza virus has become clear. To overcome the shortcomings of current influenza vaccines, eliciting both humoral and cellular immunity is imperative. Today, several new vaccines such as infection-permissive and recombinant T cell inducing vaccines, are being developed and show promising results. These vaccines will allow us to stay several steps ahead of the constantly evolving influenza virus.},
  articleno    = {33},
  author       = {Spitaels, Jan and Roose, Kenny and Saelens, Xavier},
  issn         = {2076-393X},
  journal      = {VACCINES},
  language     = {eng},
  number       = {4},
  pages        = {23},
  title        = {In\unmatched{fb02}uenza and memory T cells : how to awake the force},
  url          = {http://dx.doi.org/10.3390/vaccines4040033},
  volume       = {4},
  year         = {2016},
}

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