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Exacerbation of pre-existing diabetes insipidus during pregnancy, mechanisms and management

Lloyd Tack (UGent) , Guy T'Sjoen (UGent) and Bruno Lapauw (UGent)
(2016) ACTA CLINICA BELGICA. 72(3). p.213-216
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Abstract
During pregnancy, physiological changes in osmotic homeostasis cause water retention. If excessive, this can cause gestational diabetes insipidus (DI), particularly in patients with already impaired vasopressin secretion. We present the case of a 34-year-old patient with pre-existing hypopituitarism who experienced a transient exacerbation of her DI during a twin pregnancy. In contrast to typical gestational DI, polyuria and polydipsia occurred during the first trimester and remained stable thereafter. This case highlights a challenging clinical entity of which pathophysiology, diagnostic approach and treatment will be discussed.
Keywords
Gestational diabetes insipidus, Diabetes insipidus, Pregnancy, Hypopituitarism, dDAVP, HUMAN CHORIONIC-GONADOTROPIN, PLASMA OSMOLALITY, VASOPRESSIN, GESTATION, THIRST, SERIAL

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Citation

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MLA
Tack, Lloyd, Guy T’Sjoen, and Bruno Lapauw. “Exacerbation of Pre-existing Diabetes Insipidus During Pregnancy, Mechanisms and Management.” ACTA CLINICA BELGICA 72.3 (2016): 213–216. Print.
APA
Tack, L., T’Sjoen, G., & Lapauw, B. (2016). Exacerbation of pre-existing diabetes insipidus during pregnancy, mechanisms and management. ACTA CLINICA BELGICA, 72(3), 213–216.
Chicago author-date
Tack, Lloyd, Guy T’Sjoen, and Bruno Lapauw. 2016. “Exacerbation of Pre-existing Diabetes Insipidus During Pregnancy, Mechanisms and Management.” Acta Clinica Belgica 72 (3): 213–216.
Chicago author-date (all authors)
Tack, Lloyd, Guy T’Sjoen, and Bruno Lapauw. 2016. “Exacerbation of Pre-existing Diabetes Insipidus During Pregnancy, Mechanisms and Management.” Acta Clinica Belgica 72 (3): 213–216.
Vancouver
1.
Tack L, T’Sjoen G, Lapauw B. Exacerbation of pre-existing diabetes insipidus during pregnancy, mechanisms and management. ACTA CLINICA BELGICA. 2016;72(3):213–6.
IEEE
[1]
L. Tack, G. T’Sjoen, and B. Lapauw, “Exacerbation of pre-existing diabetes insipidus during pregnancy, mechanisms and management,” ACTA CLINICA BELGICA, vol. 72, no. 3, pp. 213–216, 2016.
@article{8525244,
  abstract     = {During pregnancy, physiological changes in osmotic homeostasis cause water retention. If excessive, this can cause gestational diabetes insipidus (DI), particularly in patients with already impaired vasopressin secretion. We present the case of a 34-year-old patient with pre-existing hypopituitarism who experienced a transient exacerbation of her DI during a twin pregnancy. In contrast to typical gestational DI, polyuria and polydipsia occurred during the first trimester and remained stable thereafter. This case highlights a challenging clinical entity of which pathophysiology, diagnostic approach and treatment will be discussed.},
  author       = {Tack, Lloyd and T'Sjoen, Guy and Lapauw, Bruno},
  issn         = {1784-3286},
  journal      = {ACTA CLINICA BELGICA},
  keywords     = {Gestational diabetes insipidus,Diabetes insipidus,Pregnancy,Hypopituitarism,dDAVP,HUMAN CHORIONIC-GONADOTROPIN,PLASMA OSMOLALITY,VASOPRESSIN,GESTATION,THIRST,SERIAL},
  language     = {eng},
  number       = {3},
  pages        = {213--216},
  title        = {Exacerbation of pre-existing diabetes insipidus during pregnancy, mechanisms and management},
  url          = {http://dx.doi.org/10.1080/17843286.2016.1235244},
  volume       = {72},
  year         = {2016},
}
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