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Long non-coding RNAs in cutaneous melanoma : clinical perspectives

Eva Hulstaert (UGent), Lieve Brochez (UGent), Pieter-Jan Volders (UGent), Jo Vandesompele (UGent) and Pieter Mestdagh (UGent)
(2017) ONCOTARGET. 8(26). p.43470-43480
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Abstract
Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding potential. There is growing evidence that lncRNAs play an important role in gene regulation, including oncogenesis. We present 13 lncRNA genes involved in the pathogenesis of cutaneous melanoma through a variety of pathways and molecular interactions. Some of these lncRNAs are possible biomarkers or therapeutic targets for malignant melanoma.
Keywords
long non-coding RNA, melanoma, biomarkers, cancer therapy, EPITHELIAL-MESENCHYMAL TRANSITION, CELL LUNG-CANCER, POOR-PROGNOSIS, DOWN-REGULATION, GASTRIC-CANCER, METASTATIC MELANOMA, COLORECTAL-CANCER, PROSTATE-CANCER, CERVICAL-CANCER, LNCRNA GAS5

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Citation

Please use this url to cite or link to this publication:

Chicago
Hulstaert, Eva, Lieve Brochez, Pieter-Jan Volders, Jo Vandesompele, and Pieter Mestdagh. 2017. “Long Non-coding RNAs in Cutaneous Melanoma : Clinical Perspectives.” Oncotarget 8 (26): 43470–43480.
APA
Hulstaert, E., Brochez, L., Volders, P.-J., Vandesompele, J., & Mestdagh, P. (2017). Long non-coding RNAs in cutaneous melanoma : clinical perspectives. ONCOTARGET, 8(26), 43470–43480.
Vancouver
1.
Hulstaert E, Brochez L, Volders P-J, Vandesompele J, Mestdagh P. Long non-coding RNAs in cutaneous melanoma : clinical perspectives. ONCOTARGET. 2017;8(26):43470–80.
MLA
Hulstaert, Eva, Lieve Brochez, Pieter-Jan Volders, et al. “Long Non-coding RNAs in Cutaneous Melanoma : Clinical Perspectives.” ONCOTARGET 8.26 (2017): 43470–43480. Print.
@article{8525149,
  abstract     = {Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding potential. There is growing evidence that lncRNAs play an important role in gene regulation, including oncogenesis. We present 13 lncRNA genes involved in the pathogenesis of cutaneous melanoma through a variety of pathways and molecular interactions. Some of these lncRNAs are possible biomarkers or therapeutic targets for malignant melanoma.},
  author       = {Hulstaert, Eva and Brochez, Lieve and Volders, Pieter-Jan and Vandesompele, Jo and Mestdagh, Pieter},
  issn         = {1949-2553},
  journal      = {ONCOTARGET},
  keyword      = {long non-coding RNA,melanoma,biomarkers,cancer therapy,EPITHELIAL-MESENCHYMAL TRANSITION,CELL LUNG-CANCER,POOR-PROGNOSIS,DOWN-REGULATION,GASTRIC-CANCER,METASTATIC MELANOMA,COLORECTAL-CANCER,PROSTATE-CANCER,CERVICAL-CANCER,LNCRNA GAS5},
  language     = {eng},
  number       = {26},
  pages        = {43470--43480},
  title        = {Long non-coding RNAs in cutaneous melanoma : clinical perspectives},
  url          = {http://dx.doi.org/10.18632/oncotarget.16478},
  volume       = {8},
  year         = {2017},
}

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