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Long non-coding RNAs in cutaneous melanoma : clinical perspectives

Eva Hulstaert UGent, Lieve Brochez UGent, Pieter-Jan Volders UGent, Jo Vandesompele UGent and Pieter Mestdagh UGent (2017) ONCOTARGET. 8(26). p.43470-43480
abstract
Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding potential. There is growing evidence that lncRNAs play an important role in gene regulation, including oncogenesis. We present 13 lncRNA genes involved in the pathogenesis of cutaneous melanoma through a variety of pathways and molecular interactions. Some of these lncRNAs are possible biomarkers or therapeutic targets for malignant melanoma.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
long non-coding RNA, melanoma, biomarkers, cancer therapy, EPITHELIAL-MESENCHYMAL TRANSITION, CELL LUNG-CANCER, POOR-PROGNOSIS, DOWN-REGULATION, GASTRIC-CANCER, METASTATIC MELANOMA, COLORECTAL-CANCER, PROSTATE-CANCER, CERVICAL-CANCER, LNCRNA GAS5
journal title
ONCOTARGET
Oncotarget
volume
8
issue
26
pages
43470 - 43480
Web of Science type
Review
Web of Science id
000405493400141
ISSN
1949-2553
DOI
10.18632/oncotarget.16478
language
English
UGent publication?
yes
classification
A1
copyright statement
I have retained and own the full copyright for this publication
id
8525149
handle
http://hdl.handle.net/1854/LU-8525149
date created
2017-06-26 13:17:41
date last changed
2017-12-14 09:58:03
@article{8525149,
  abstract     = {Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding potential. There is growing evidence that lncRNAs play an important role in gene regulation, including oncogenesis. We present 13 lncRNA genes involved in the pathogenesis of cutaneous melanoma through a variety of pathways and molecular interactions. Some of these lncRNAs are possible biomarkers or therapeutic targets for malignant melanoma.},
  author       = {Hulstaert, Eva and Brochez, Lieve and Volders, Pieter-Jan and Vandesompele, Jo and Mestdagh, Pieter},
  issn         = {1949-2553},
  journal      = {ONCOTARGET},
  keyword      = {long non-coding RNA,melanoma,biomarkers,cancer therapy,EPITHELIAL-MESENCHYMAL TRANSITION,CELL LUNG-CANCER,POOR-PROGNOSIS,DOWN-REGULATION,GASTRIC-CANCER,METASTATIC MELANOMA,COLORECTAL-CANCER,PROSTATE-CANCER,CERVICAL-CANCER,LNCRNA GAS5},
  language     = {eng},
  number       = {26},
  pages        = {43470--43480},
  title        = {Long non-coding RNAs in cutaneous melanoma : clinical perspectives},
  url          = {http://dx.doi.org/10.18632/oncotarget.16478},
  volume       = {8},
  year         = {2017},
}

Chicago
Hulstaert, Eva, Lieve Brochez, Pieter-Jan Volders, Jo Vandesompele, and Pieter Mestdagh. 2017. “Long Non-coding RNAs in Cutaneous Melanoma : Clinical Perspectives.” Oncotarget 8 (26): 43470–43480.
APA
Hulstaert, E., Brochez, L., Volders, P.-J., Vandesompele, J., & Mestdagh, P. (2017). Long non-coding RNAs in cutaneous melanoma : clinical perspectives. ONCOTARGET, 8(26), 43470–43480.
Vancouver
1.
Hulstaert E, Brochez L, Volders P-J, Vandesompele J, Mestdagh P. Long non-coding RNAs in cutaneous melanoma : clinical perspectives. ONCOTARGET. 2017;8(26):43470–80.
MLA
Hulstaert, Eva, Lieve Brochez, Pieter-Jan Volders, et al. “Long Non-coding RNAs in Cutaneous Melanoma : Clinical Perspectives.” ONCOTARGET 8.26 (2017): 43470–43480. Print.