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Perianal Paget’s disease : case report and review of the literature

Hugo Bontinck UGent, JULIE BONTINCK, T Rondou, Piet Pattyn UGent and F Lockefeer (2016) ACTA CHIRURGICA BELGICA. 116(3). p.187-192
abstract
A peri-anal skin lesion, often eczema-like and with symptoms of pruritus, that does not resolve after classical local therapy should be biopsied. We present a case of peri-anal extramammary Paget's disease ( EMDP) and associated anal adenocarcinoma. Reviewing the literature, more than 30% of patients with EMDP present a second primary tumour in their past, present or future history. In Europe, the risk of developing a new primary tumour in patients with this condition is increased compared with the standard population. In cases of peri-anal Paget's disease (PPD), specific histochemical markers allow us to differentiate between a primary and a secondary form, the secondary one is strongly associated with colorectal and anal tumours. We provide information about the most commonly suggested therapy for PPD with or without associated malignancy and about the recommended follow-up.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
Anal adenocarcinoma, CK 7, CK 20, CDX2, GCDFP-15, extramammary Paget, Pagetoid phenomenon, perianal Paget disease, RECTAL ADENOCARCINOMA, MANAGEMENT, EXCISION, REGION, MALIGNANCIES, RADIOTHERAPY, EXPRESSION, EXPERIENCE, PROGNOSIS, DIAGNOSIS
journal title
ACTA CHIRURGICA BELGICA
Acta Chir. Belg.
volume
116
issue
3
pages
187 - 192
Web of Science type
Review
Web of Science id
000389705200009
JCR category
SURGERY
JCR impact factor
0.494 (2016)
JCR rank
182/196 (2016)
JCR quartile
4 (2016)
ISSN
0001-5458
DOI
10.1080/00015458.2016.1139832
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
8523747
handle
http://hdl.handle.net/1854/LU-8523747
date created
2017-06-14 12:10:22
date last changed
2017-06-29 08:36:46
@article{8523747,
  abstract     = {A peri-anal skin lesion, often eczema-like and with symptoms of pruritus, that does not resolve after classical local therapy should be biopsied. We present a case of peri-anal extramammary Paget's disease ( EMDP) and associated anal adenocarcinoma. Reviewing the literature, more than 30\% of patients with EMDP present a second primary tumour in their past, present or future history. In Europe, the risk of developing a new primary tumour in patients with this condition is increased compared with the standard population. In cases of peri-anal Paget's disease (PPD), specific histochemical markers allow us to differentiate between a primary and a secondary form, the secondary one is strongly associated with colorectal and anal tumours. We provide information about the most commonly suggested therapy for PPD with or without associated malignancy and about the recommended follow-up.},
  author       = {Bontinck, Hugo and BONTINCK, JULIE and Rondou, T and Pattyn, Piet and Lockefeer, F},
  issn         = {0001-5458},
  journal      = {ACTA CHIRURGICA BELGICA},
  keyword      = {Anal adenocarcinoma,CK 7,CK 20,CDX2,GCDFP-15,extramammary Paget,Pagetoid phenomenon,perianal Paget disease,RECTAL ADENOCARCINOMA,MANAGEMENT,EXCISION,REGION,MALIGNANCIES,RADIOTHERAPY,EXPRESSION,EXPERIENCE,PROGNOSIS,DIAGNOSIS},
  language     = {eng},
  number       = {3},
  pages        = {187--192},
  title        = {Perianal Paget{\textquoteright}s disease : case report and review of the literature},
  url          = {http://dx.doi.org/10.1080/00015458.2016.1139832},
  volume       = {116},
  year         = {2016},
}

Chicago
Bontinck, Hugo, JULIE BONTINCK, T Rondou, Piet Pattyn, and F Lockefeer. 2016. “Perianal Paget’s Disease : Case Report and Review of the Literature.” Acta Chirurgica Belgica 116 (3): 187–192.
APA
Bontinck, H., BONTINCK, J., Rondou, T., Pattyn, P., & Lockefeer, F. (2016). Perianal Paget’s disease : case report and review of the literature. ACTA CHIRURGICA BELGICA, 116(3), 187–192.
Vancouver
1.
Bontinck H, BONTINCK J, Rondou T, Pattyn P, Lockefeer F. Perianal Paget’s disease : case report and review of the literature. ACTA CHIRURGICA BELGICA. 2016;116(3):187–92.
MLA
Bontinck, Hugo, JULIE BONTINCK, T Rondou, et al. “Perianal Paget’s Disease : Case Report and Review of the Literature.” ACTA CHIRURGICA BELGICA 116.3 (2016): 187–192. Print.