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Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)

Christophe Vieira UGent, Julie Gaubert, Olivier De Clerck UGent, Claude Payri, Gérald Culioli and Olivier P Thomas (2017) PHYTOCHEMISTRY REVIEWS. 16(1). p.1-17
abstract
Although Lobophora belongs to a marine algal family (Dictyotaceae) that produces a large array of secondary metabolites, it has received little attention compared to other genera, such as Dictyota, in terms of natural compounds isolation and characterization. However, metabolites produced by Lobophora species have been found to exhibit a wide array of bioactivities including pharmacological (e.g. antibacterial, antiviral, antioxidant, antitumoral), pesticidal, and ecological. This review aims to report the state-of-the-art of the natural products isolated from Lobophora species (Dictyotales, Phaeophyceae) and their associated bioactivities. All bioactivities documented in the literature are reported, therefore including studies for which pure active substances were described, as well as studies limited to extracts or fractions. From the early 1980s until today, 49 scientific works have been published on Lobophora chemistry and bioactivity, among which 40 have reported bioactivities. Only six studies, however, have identified, characterized and tested no less than 23 bioactive pure compounds (three C-21 polyunsaturated alcohols, three fatty-acids, a macrolactone, 11 polyketides, a few sulfated polysaccharides, three sulfolipids, a tocopherol derivative). The present review intends to raise awareness of chemists and biologists given the recent significant taxonomic progress of this brown algal genus, which holds a promising plethora of natural products yet to be discovered with ecological and pharmacological properties.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
MARINE CHEMICAL ECOLOGY, BRAZILIAN SEAWEEDS, CARBONYL-COMPOUNDS, TROPICAL SEAWEEDS, NATURAL-PRODUCTS, CORAL-REEFS, FATTY-ACIDS, HONG-KONG, VITAMIN-E, MACROALGAE, Bioactivity, Brown algae, Lobophora, Natural products
journal title
PHYTOCHEMISTRY REVIEWS
Phytochem. Rev.
volume
16
issue
1
pages
1 - 17
Web of Science type
Review
Web of Science id
000397921500001
ISSN
1568-7767
1572-980X
DOI
10.1007/s11101-015-9445-x
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
8518473
handle
http://hdl.handle.net/1854/LU-8518473
date created
2017-04-24 11:54:16
date last changed
2017-08-04 07:47:33
@article{8518473,
  abstract     = {Although Lobophora belongs to a marine algal family (Dictyotaceae) that produces a large array of secondary metabolites, it has received little attention compared to other genera, such as Dictyota, in terms of natural compounds isolation and characterization. However, metabolites produced by Lobophora species have been found to exhibit a wide array of bioactivities including pharmacological (e.g. antibacterial, antiviral, antioxidant, antitumoral), pesticidal, and ecological. This review aims to report the state-of-the-art of the natural products isolated from Lobophora species (Dictyotales, Phaeophyceae) and their associated bioactivities. All bioactivities documented in the literature are reported, therefore including studies for which pure active substances were described, as well as studies limited to extracts or fractions. From the early 1980s until today, 49 scientific works have been published on Lobophora chemistry and bioactivity, among which 40 have reported bioactivities. Only six studies, however, have identified, characterized and tested no less than 23 bioactive pure compounds (three C-21 polyunsaturated alcohols, three fatty-acids, a macrolactone, 11 polyketides, a few sulfated polysaccharides, three sulfolipids, a tocopherol derivative). The present review intends to raise awareness of chemists and biologists given the recent significant taxonomic progress of this brown algal genus, which holds a promising plethora of natural products yet to be discovered with ecological and pharmacological properties.},
  author       = {Vieira, Christophe and Gaubert, Julie and De Clerck, Olivier and Payri, Claude and Culioli, G{\'e}rald and Thomas, Olivier P},
  issn         = {1568-7767},
  journal      = {PHYTOCHEMISTRY REVIEWS},
  keyword      = {MARINE CHEMICAL ECOLOGY,BRAZILIAN SEAWEEDS,CARBONYL-COMPOUNDS,TROPICAL SEAWEEDS,NATURAL-PRODUCTS,CORAL-REEFS,FATTY-ACIDS,HONG-KONG,VITAMIN-E,MACROALGAE,Bioactivity,Brown algae,Lobophora,Natural products},
  language     = {eng},
  number       = {1},
  pages        = {1--17},
  title        = {Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae)},
  url          = {http://dx.doi.org/10.1007/s11101-015-9445-x},
  volume       = {16},
  year         = {2017},
}

Chicago
Vieira, Christophe, Julie Gaubert, Olivier De Clerck, Claude Payri, Gérald Culioli, and Olivier P Thomas. 2017. “Biological Activities Associated to the Chemodiversity of the Brown Algae Belonging to Genus Lobophora (Dictyotales, Phaeophyceae).” Phytochemistry Reviews 16 (1): 1–17.
APA
Vieira, C., Gaubert, J., De Clerck, O., Payri, C., Culioli, G., & Thomas, O. P. (2017). Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae). PHYTOCHEMISTRY REVIEWS, 16(1), 1–17.
Vancouver
1.
Vieira C, Gaubert J, De Clerck O, Payri C, Culioli G, Thomas OP. Biological activities associated to the chemodiversity of the brown algae belonging to genus Lobophora (Dictyotales, Phaeophyceae). PHYTOCHEMISTRY REVIEWS. 2017;16(1):1–17.
MLA
Vieira, Christophe, Julie Gaubert, Olivier De Clerck, et al. “Biological Activities Associated to the Chemodiversity of the Brown Algae Belonging to Genus Lobophora (Dictyotales, Phaeophyceae).” PHYTOCHEMISTRY REVIEWS 16.1 (2017): 1–17. Print.