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Elucidation and visualization of solid-state transformation and mixing in a pharmaceutical mini hot melt extrusion process using in-line Raman spectroscopy

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NIR, CO2, Hot-melt extrusion, Raman spectroscopy, Solid-state transformation, Residence time distribution, Mixing, Transport, Recirculation time, NIR, CO2

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Citation

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Chicago
Van Renterghem, Jeroen, Ashish Kumar, Chris Vervaet, Jean Paul Remon, Ingmar Nopens, Yvan Vander Heyden, and Thomas De Beer. 2017. “Elucidation and Visualization of Solid-state Transformation and Mixing in a Pharmaceutical Mini Hot Melt Extrusion Process Using In-line Raman Spectroscopy.” International Journal of Pharmaceutics 517 (1-2): 119–127.
APA
Van Renterghem, J., Kumar, A., Vervaet, C., Remon, J. P., Nopens, I., Vander Heyden, Y., & De Beer, T. (2017). Elucidation and visualization of solid-state transformation and mixing in a pharmaceutical mini hot melt extrusion process using in-line Raman spectroscopy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 517(1-2), 119–127.
Vancouver
1.
Van Renterghem J, Kumar A, Vervaet C, Remon JP, Nopens I, Vander Heyden Y, et al. Elucidation and visualization of solid-state transformation and mixing in a pharmaceutical mini hot melt extrusion process using in-line Raman spectroscopy. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2017;517(1-2):119–27.
MLA
Van Renterghem, Jeroen, Ashish Kumar, Chris Vervaet, et al. “Elucidation and Visualization of Solid-state Transformation and Mixing in a Pharmaceutical Mini Hot Melt Extrusion Process Using In-line Raman Spectroscopy.” INTERNATIONAL JOURNAL OF PHARMACEUTICS 517.1-2 (2017): 119–127. Print.
@article{8517256,
  author       = {Van Renterghem, Jeroen and Kumar, Ashish and Vervaet, Chris and Remon, Jean Paul and Nopens, Ingmar and Vander Heyden, Yvan and De Beer, Thomas},
  issn         = {0378-5173},
  journal      = {INTERNATIONAL JOURNAL OF PHARMACEUTICS},
  keyword      = {NIR,CO2,Hot-melt extrusion,Raman spectroscopy,Solid-state transformation,Residence time distribution,Mixing,Transport,Recirculation time,NIR,CO2},
  language     = {eng},
  number       = {1-2},
  pages        = {119--127},
  title        = {Elucidation and visualization of solid-state transformation and mixing in a pharmaceutical mini hot melt extrusion process using in-line Raman spectroscopy},
  url          = {http://dx.doi.org/10.1016/j.ijpharm.2016.11.065},
  volume       = {517},
  year         = {2017},
}

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