Advanced search
1 file | 1.47 MB Add to list

Photoinduced cross-linking of short furan-modified DNA on surfaces

(2017) LANGMUIR. 33(5). p.1197-1201
Author
Organization
Abstract
We report for the first time the formation of site specific interstrand cross p-linked (ICL) surface -immobilized furanmodified DNA duplexes-via singlet oxygen. 102, necessary for effecting furan-mediated ICL formation, was produced in situ using methylene blue or a zinc phthalocyanine derivative (TT1) as a photosensitizer. Via surface plasmon resonance spectroscopy, we show that surface ICL was achieved, and a robust link formed that enhances the stability of the 12-mer duplex even after surface regeneration. The described method represents a novel platform technology based on surfaces with addressable and stable DNA duplexes requiring only short oligonudeotides.
Keywords
DIRECTED IMMOBILIZATION, PLASMON RESONANCE, PHTHALOCYANINES, EFFICIENT, ANTIBODY, CANCER, WATER

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 1.47 MB

Citation

Please use this url to cite or link to this publication:

MLA
Véliz Montes, Cinthya et al. “Photoinduced Cross-linking of Short Furan-modified DNA on Surfaces.” LANGMUIR 33.5 (2017): 1197–1201. Print.
APA
Véliz Montes, C., Memczak, H., Gyssels, E., Torres, T., Madder, A., & Schneider, R. J. (2017). Photoinduced cross-linking of short furan-modified DNA on surfaces. LANGMUIR, 33(5), 1197–1201.
Chicago author-date
Véliz Montes, Cinthya, Henry Memczak, Ellen Gyssels, Tomás Torres, Annemieke Madder, and Rudolf J Schneider. 2017. “Photoinduced Cross-linking of Short Furan-modified DNA on Surfaces.” Langmuir 33 (5): 1197–1201.
Chicago author-date (all authors)
Véliz Montes, Cinthya, Henry Memczak, Ellen Gyssels, Tomás Torres, Annemieke Madder, and Rudolf J Schneider. 2017. “Photoinduced Cross-linking of Short Furan-modified DNA on Surfaces.” Langmuir 33 (5): 1197–1201.
Vancouver
1.
Véliz Montes C, Memczak H, Gyssels E, Torres T, Madder A, Schneider RJ. Photoinduced cross-linking of short furan-modified DNA on surfaces. LANGMUIR. 2017;33(5):1197–201.
IEEE
[1]
C. Véliz Montes, H. Memczak, E. Gyssels, T. Torres, A. Madder, and R. J. Schneider, “Photoinduced cross-linking of short furan-modified DNA on surfaces,” LANGMUIR, vol. 33, no. 5, pp. 1197–1201, 2017.
@article{8516375,
  abstract     = {We report for the first time the formation of site specific interstrand cross p-linked (ICL) surface -immobilized furanmodified DNA duplexes-via singlet oxygen. 102, necessary for effecting furan-mediated ICL formation, was produced in situ using methylene blue or a zinc phthalocyanine derivative (TT1) as a photosensitizer. Via surface plasmon resonance spectroscopy, we show that surface ICL was achieved, and a robust link formed that enhances the stability of the 12-mer duplex even after surface regeneration. The described method represents a novel platform technology based on surfaces with addressable and stable DNA duplexes requiring only short oligonudeotides.},
  author       = {Véliz Montes, Cinthya and Memczak, Henry and Gyssels, Ellen and Torres, Tomás and Madder, Annemieke and Schneider, Rudolf J},
  issn         = {0743-7463},
  journal      = {LANGMUIR},
  keywords     = {DIRECTED IMMOBILIZATION,PLASMON RESONANCE,PHTHALOCYANINES,EFFICIENT,ANTIBODY,CANCER,WATER},
  language     = {eng},
  number       = {5},
  pages        = {1197--1201},
  title        = {Photoinduced cross-linking of short furan-modified DNA on surfaces},
  url          = {http://dx.doi.org/10.1021/acs.langmuir.6b03855},
  volume       = {33},
  year         = {2017},
}

Altmetric
View in Altmetric
Web of Science
Times cited: