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Outcome after laparoscopic and open resections of posterosuperior segments of the liver

VINCENZO SCUDERI, L Barkhatov, Roberto Montalti, F Ratti, F Cipriani, F Pardo, H Tranchart, I Dagher, F Rotellar, M Abu Hilal, et al. (2017) BRITISH JOURNAL OF SURGERY. 104(6). p.751-759
abstract
Background: Laparoscopic resection of posterosuperior (PS) segments of the liver is hindered by limited visualization and curvilinear resection planes. The aim of this study was to compare outcomes after open and laparoscopic liver resections of PS segments. Methods: Patients who underwent minor open liver resection (OLR) and laparoscopic liver resection (LLR) between 2006 and 2014 were identified from the institutional databases of seven tertiary referral European hepatobiliary surgical units. Propensity score-matched analysis was used to match groups for known confounders. Perioperative outcomes including complications were assessed using the Dindo-Clavien classification, and the comprehensive complication index was calculated. Survival was analysed with the Kaplan-Meier method. Results: Some 170 patients underwent OLR and 148 had LLR. After propensity score-matched analysis, 86 patients remained in both groups. Overall postoperative complication rates were significantly higher after OLR compared with LLR: 28 versus 14 per cent respectively (P = 0039). The mean(s.d.) comprehensive complication index was higher in the OLR group, although the difference was not statistically significant (267(166) versus 183(80) in the LLR group; P = 0108). The mean(s.d.) duration of required analgesia and the median (range) duration of postoperative hospital stay were significantly shorter in the LLR group: 30(11) days versus 16(08) days in the OLR group (P<0001), and 6 (3-44) versus 4 (1-11) days (P<0001), respectively. The 3-year recurrence-free survival rates for patients with hepatocellular carcinoma (37 per cent for OLRversus 30 per cent for LLR; P=0534) and those with colorectal liver metastases (36 versus 36 per cent respectively; P=0440) were not significantly different between the groups. Conclusion: LLR of tumours in PS segments is feasible in selected patients. LLR is associated with fewer complications and does not compromise survival compared with OLR.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (proceedingsPaper)
publication status
published
subject
keyword
HEPATOCELLULAR-CARCINOMA, OPEN HEPATECTOMY, LONG-TERM, METASTASES, SURGERY, TUMORS, SECTIONECTOMY, EXPERIENCE, MANAGEMENT, MORBIDITY
journal title
BRITISH JOURNAL OF SURGERY
Br. J. Surg.
volume
104
issue
6
pages
751 - 759
conference name
17th Belgian Surgical Week ; Annual meeting of the Royal Belgian Surgical Society
conference location
Brussels, Belgium
conference start
2016-05-19
conference end
2016-05-21
Web of Science type
Article; Proceedings Paper
ISSN
0007-1323
DOI
10.1002/bjs.10489
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
8514965
handle
http://hdl.handle.net/1854/LU-8514965
date created
2017-03-21 07:41:22
date last changed
2017-06-29 09:14:15
@article{8514965,
  abstract     = {Background: Laparoscopic resection of posterosuperior (PS) segments of the liver is hindered by limited visualization and curvilinear resection planes. The aim of this study was to compare outcomes after open and laparoscopic liver resections of PS segments. 
Methods: Patients who underwent minor open liver resection (OLR) and laparoscopic liver resection (LLR) between 2006 and 2014 were identified from the institutional databases of seven tertiary referral European hepatobiliary surgical units. Propensity score-matched analysis was used to match groups for known confounders. Perioperative outcomes including complications were assessed using the Dindo-Clavien classification, and the comprehensive complication index was calculated. Survival was analysed with the Kaplan-Meier method. 
Results: Some 170 patients underwent OLR and 148 had LLR. After propensity score-matched analysis, 86 patients remained in both groups. Overall postoperative complication rates were significantly higher after OLR compared with LLR: 28 versus 14 per cent respectively (P = 0039). The mean(s.d.) comprehensive complication index was higher in the OLR group, although the difference was not statistically significant (267(166) versus 183(80) in the LLR group; P = 0108). The mean(s.d.) duration of required analgesia and the median (range) duration of postoperative hospital stay were significantly shorter in the LLR group: 30(11) days versus 16(08) days in the OLR group (P{\textlangle}0001), and 6 (3-44) versus 4 (1-11) days (P{\textlangle}0001), respectively. The 3-year recurrence-free survival rates for patients with hepatocellular carcinoma (37 per cent for OLRversus 30 per cent for LLR; P=0534) and those with colorectal liver metastases (36 versus 36 per cent respectively; P=0440) were not significantly different between the groups. 
Conclusion: LLR of tumours in PS segments is feasible in selected patients. LLR is associated with fewer complications and does not compromise survival compared with OLR.},
  author       = {SCUDERI, VINCENZO and Barkhatov, L and Montalti, Roberto and Ratti, F and Cipriani, F and Pardo, F and Tranchart, H and Dagher, I and Rotellar, F and Abu Hilal, M and Edwin, B and Vivarelli, M and Aldrighetti, L and Troisi, Roberto},
  issn         = {0007-1323},
  journal      = {BRITISH JOURNAL OF SURGERY},
  keyword      = {HEPATOCELLULAR-CARCINOMA,OPEN HEPATECTOMY,LONG-TERM,METASTASES,SURGERY,TUMORS,SECTIONECTOMY,EXPERIENCE,MANAGEMENT,MORBIDITY},
  language     = {eng},
  location     = {Brussels, Belgium},
  number       = {6},
  pages        = {751--759},
  title        = {Outcome after laparoscopic and open resections of posterosuperior segments of the liver},
  url          = {http://dx.doi.org/10.1002/bjs.10489},
  volume       = {104},
  year         = {2017},
}

Chicago
SCUDERI, VINCENZO, L Barkhatov, Roberto Montalti, F Ratti, F Cipriani, F Pardo, H Tranchart, et al. 2017. “Outcome After Laparoscopic and Open Resections of Posterosuperior Segments of the Liver.” British Journal of Surgery 104 (6): 751–759.
APA
SCUDERI, V., Barkhatov, L., Montalti, R., Ratti, F., Cipriani, F., Pardo, F., Tranchart, H., et al. (2017). Outcome after laparoscopic and open resections of posterosuperior segments of the liver. BRITISH JOURNAL OF SURGERY, 104(6), 751–759. Presented at the 17th Belgian Surgical Week ; Annual meeting of the Royal Belgian Surgical Society.
Vancouver
1.
SCUDERI V, Barkhatov L, Montalti R, Ratti F, Cipriani F, Pardo F, et al. Outcome after laparoscopic and open resections of posterosuperior segments of the liver. BRITISH JOURNAL OF SURGERY. 2017;104(6):751–9.
MLA
SCUDERI, VINCENZO, L Barkhatov, Roberto Montalti, et al. “Outcome After Laparoscopic and Open Resections of Posterosuperior Segments of the Liver.” BRITISH JOURNAL OF SURGERY 104.6 (2017): 751–759. Print.