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First results of the Flemish colorectal cancer screening program : start-up-period late 2013

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Abstract
Background & study aims : Investigation of the first participation rate and follow-up results of the Flemish colorectal cancer screening program. Patients & methods : In 2013 five age cohorts with an even age between 66 and 74 year old (n = 243 335) were invited by mail to return a completed iFOBT. Participants who tested positive (>= 75ng/ml) were referred to a follow-up colonoscopy. Results : Participation rate was 48.4% (n = 117 774). Overall positivity rate was 10.1%, and 78.1% of those tested positive underwent a colonoscopy. The positive predictive value of colonoscopy for CRC was 8.2%, for advanced adenoma 16.9% and for non-advanced adenoma 36.5%. Conclusion : Based on the EU-guidelines 35% was expected as participation for a first screening round, thus a participation rate of 48.4% is more than acceptable for a first screening year. The high positivity rate can partly be explained by including only the older ages in the start-up-period and by the first year of mass screening in Flanders.
Keywords
OCCULT BLOOD-TEST, IMMUNOCHEMICAL TEST, INVITATION STRATEGIES, COST-EFFECTIVENESS, REPORTED BARRIERS, RANDOMIZED-TRIAL, PILOT PROGRAM, MIXED-METHODS, LOW-INCOME, POPULATION, colorectal cancer, screening, prevention, immunochemical faecal occult, blood test (iFOBT), participation, Flanders

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Chicago
Hoeck, Sarah, Sarah Pringels, Eliane Kellen, Koen Van Herck, Patrick Martens, Erik Van Limbergen, Julie Francart, and Guido Van Hal. 2016. “First Results of the Flemish Colorectal Cancer Screening Program : Start-up-period Late 2013.” Acta Gastro-enterologica Belgica 79 (4): 421–428.
APA
Hoeck, S., Pringels, S., Kellen, E., Van Herck, K., Martens, P., Van Limbergen, E., Francart, J., et al. (2016). First results of the Flemish colorectal cancer screening program : start-up-period late 2013. ACTA GASTRO-ENTEROLOGICA BELGICA, 79(4), 421–428.
Vancouver
1.
Hoeck S, Pringels S, Kellen E, Van Herck K, Martens P, Van Limbergen E, et al. First results of the Flemish colorectal cancer screening program : start-up-period late 2013. ACTA GASTRO-ENTEROLOGICA BELGICA. 2016;79(4):421–8.
MLA
Hoeck, Sarah, Sarah Pringels, Eliane Kellen, et al. “First Results of the Flemish Colorectal Cancer Screening Program : Start-up-period Late 2013.” ACTA GASTRO-ENTEROLOGICA BELGICA 79.4 (2016): 421–428. Print.
@article{8513142,
  abstract     = {Background \& study aims : Investigation of the first participation rate and follow-up results of the Flemish colorectal cancer screening program. 
Patients \& methods : In 2013 five age cohorts with an even age between 66 and 74 year old (n = 243 335) were invited by mail to return a completed iFOBT. Participants who tested positive ({\textrangle}= 75ng/ml) were referred to a follow-up colonoscopy. 
Results : Participation rate was 48.4\% (n = 117 774). Overall positivity rate was 10.1\%, and 78.1\% of those tested positive underwent a colonoscopy. The positive predictive value of colonoscopy for CRC was 8.2\%, for advanced adenoma 16.9\% and for non-advanced adenoma 36.5\%. 
Conclusion : Based on the EU-guidelines 35\% was expected as participation for a first screening round, thus a participation rate of 48.4\% is more than acceptable for a first screening year. The high positivity rate can partly be explained by including only the older ages in the start-up-period and by the first year of mass screening in Flanders.},
  author       = {Hoeck, Sarah and Pringels, Sarah and Kellen, Eliane and Van Herck, Koen and Martens, Patrick and Van Limbergen, Erik and Francart, Julie and Van Hal, Guido},
  issn         = {0001-5644},
  journal      = {ACTA GASTRO-ENTEROLOGICA BELGICA},
  keyword      = {OCCULT BLOOD-TEST,IMMUNOCHEMICAL TEST,INVITATION STRATEGIES,COST-EFFECTIVENESS,REPORTED BARRIERS,RANDOMIZED-TRIAL,PILOT PROGRAM,MIXED-METHODS,LOW-INCOME,POPULATION,colorectal cancer,screening,prevention,immunochemical faecal occult,blood test (iFOBT),participation,Flanders},
  language     = {eng},
  number       = {4},
  pages        = {421--428},
  title        = {First results of the Flemish colorectal cancer screening program : start-up-period late 2013},
  volume       = {79},
  year         = {2016},
}

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