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3D-printing techniques in a medical setting : a systematic literature review

Philip Tack (UGent) , Jan Victor (UGent) , Paul Gemmel (UGent) and Lieven Annemans (UGent)
Author
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Abstract
Background: Three-dimensional (3D) printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients. This paper summarizes the literature on surgical 3D-printing applications used on patients, with a focus on reported clinical and economic outcomes. Methods: Three major literature databases were screened for case series (more than three cases described in the same study) and trials of surgical applications of 3D printing in humans. Results: 227 surgical papers were analyzed and summarized using an evidence table. The papers described the use of 3D printing for surgical guides, anatomical models, and custom implants. 3D printing is used in multiple surgical domains, such as orthopedics, maxillofacial surgery, cranial surgery, and spinal surgery. In general, the advantages of 3D-printed parts are said to include reduced surgical time, improved medical outcome, and decreased radiation exposure. The costs of printing and additional scans generally increase the overall cost of the procedure. Conclusion: 3D printing is well integrated in surgical practice and research. Applications vary from anatomical models mainly intended for surgical planning to surgical guides and implants. Our research suggests that there are several advantages to 3D- printed applications, but that further research is needed to determine whether the increased intervention costs can be balanced with the observable advantages of this new technology. There is a need for a formal cost-effectiveness analysis.
Keywords
TOTAL KNEE ARTHROPLASTY, PATIENT-SPECIFIC INSTRUMENTATION, COMPUTER-AIDED-DESIGN, RANDOMIZED CLINICAL-TRIAL, PEDICLE SCREW, PLACEMENT, TOTAL HIP-ARTHROPLASTY, CUSTOM-MADE IMPLANTS, RAPID, PROTOTYPING TECHNOLOGY, ORBITAL WALL DEFECTS, DRILL GUIDE TEMPLATE, 3D printing, Additive manufacturing, Innovation, Surgery, Review, Patient specific, Customized, Anatomic model

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Citation

Please use this url to cite or link to this publication:

MLA
Tack, Philip, Jan Victor, Paul Gemmel, et al. “3D-printing Techniques in a Medical Setting : a Systematic Literature Review.” BIOMEDICAL ENGINEERING ONLINE 15 (2016): n. pag. Print.
APA
Tack, Philip, Victor, J., Gemmel, P., & Annemans, L. (2016). 3D-printing techniques in a medical setting : a systematic literature review. BIOMEDICAL ENGINEERING ONLINE, 15.
Chicago author-date
Tack, Philip, Jan Victor, Paul Gemmel, and Lieven Annemans. 2016. “3D-printing Techniques in a Medical Setting : a Systematic Literature Review.” Biomedical Engineering Online 15.
Chicago author-date (all authors)
Tack, Philip, Jan Victor, Paul Gemmel, and Lieven Annemans. 2016. “3D-printing Techniques in a Medical Setting : a Systematic Literature Review.” Biomedical Engineering Online 15.
Vancouver
1.
Tack P, Victor J, Gemmel P, Annemans L. 3D-printing techniques in a medical setting : a systematic literature review. BIOMEDICAL ENGINEERING ONLINE. 2016;15.
IEEE
[1]
P. Tack, J. Victor, P. Gemmel, and L. Annemans, “3D-printing techniques in a medical setting : a systematic literature review,” BIOMEDICAL ENGINEERING ONLINE, vol. 15, 2016.
@article{8511479,
  abstract     = {Background: Three-dimensional (3D) printing has numerous applications and has gained much interest in the medical world. The constantly improving quality of 3D-printing applications has contributed to their increased use on patients. This paper summarizes the literature on surgical 3D-printing applications used on patients, with a focus on reported clinical and economic outcomes. 
Methods: Three major literature databases were screened for case series (more than three cases described in the same study) and trials of surgical applications of 3D printing in humans. 
Results: 227 surgical papers were analyzed and summarized using an evidence table. The papers described the use of 3D printing for surgical guides, anatomical models, and custom implants. 3D printing is used in multiple surgical domains, such as orthopedics, maxillofacial surgery, cranial surgery, and spinal surgery. In general, the advantages of 3D-printed parts are said to include reduced surgical time, improved medical outcome, and decreased radiation exposure. The costs of printing and additional scans generally increase the overall cost of the procedure. 
Conclusion: 3D printing is well integrated in surgical practice and research. Applications vary from anatomical models mainly intended for surgical planning to surgical guides and implants. Our research suggests that there are several advantages to 3D- printed applications, but that further research is needed to determine whether the increased intervention costs can be balanced with the observable advantages of this new technology. There is a need for a formal cost-effectiveness analysis.},
  articleno    = {115},
  author       = {Tack, Philip and Victor, Jan and Gemmel, Paul and Annemans, Lieven},
  issn         = {1475-925X},
  journal      = {BIOMEDICAL ENGINEERING ONLINE},
  keywords     = {TOTAL KNEE ARTHROPLASTY,PATIENT-SPECIFIC INSTRUMENTATION,COMPUTER-AIDED-DESIGN,RANDOMIZED CLINICAL-TRIAL,PEDICLE SCREW,PLACEMENT,TOTAL HIP-ARTHROPLASTY,CUSTOM-MADE IMPLANTS,RAPID,PROTOTYPING TECHNOLOGY,ORBITAL WALL DEFECTS,DRILL GUIDE TEMPLATE,3D printing,Additive manufacturing,Innovation,Surgery,Review,Patient specific,Customized,Anatomic model},
  language     = {eng},
  pages        = {21},
  title        = {3D-printing techniques in a medical setting : a systematic literature review},
  url          = {http://dx.doi.org/10.1186/s12938-016-0236-4},
  volume       = {15},
  year         = {2016},
}

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