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Repigmentation in vitiligo : position paper of the Vitiligo Global Issues Consensus Conference

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Abstract
The Vitiligo Global Issues Consensus Conference ( VGICC), through an international e-Delphi consensus, concluded that ` repigmentation' and ` maintenance of gained repigmentation' are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e- surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e- surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.
Keywords
repigmentation/vitiligo/pigment/repigmentation pattern/outcome measure, EPIDERMAL-CELL SUSPENSION, QUALITY-OF-LIFE, TERM-FOLLOW-UP, MELANOCYTE-STIMULATING HORMONE, HUMAN SEBACEOUS GLANDS, LONG-TERM, WNT/BETA-CATENIN, STEM-CELLS, HUMAN SKIN, UV-B

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Citation

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Chicago
Gan, Emily Y, Viktoria Eleftheriadou, Samia Esmat, Iltefat Hamzavi, Thierry Passeron, Markus Böhm, Tag Anbar, et al. 2016. “Repigmentation in Vitiligo : Position Paper of the Vitiligo Global Issues Consensus Conference.” Pigment Cell & Melanoma Research 30 (1): 28–40.
APA
Gan, E. Y., Eleftheriadou, V., Esmat, S., Hamzavi, I., Passeron, T., Böhm, M., Anbar, T., et al. (2016). Repigmentation in vitiligo : position paper of the Vitiligo Global Issues Consensus Conference. PIGMENT CELL & MELANOMA RESEARCH, 30(1), 28–40.
Vancouver
1.
Gan EY, Eleftheriadou V, Esmat S, Hamzavi I, Passeron T, Böhm M, et al. Repigmentation in vitiligo : position paper of the Vitiligo Global Issues Consensus Conference. PIGMENT CELL & MELANOMA RESEARCH. 2016;30(1):28–40.
MLA
Gan, Emily Y, Viktoria Eleftheriadou, Samia Esmat, et al. “Repigmentation in Vitiligo : Position Paper of the Vitiligo Global Issues Consensus Conference.” PIGMENT CELL & MELANOMA RESEARCH 30.1 (2016): 28–40. Print.
@article{8511369,
  abstract     = {The Vitiligo Global Issues Consensus Conference ( VGICC), through an international e-Delphi consensus, concluded that ` repigmentation' and ` maintenance of gained repigmentation' are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e- surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80\% and at least 80\% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e- surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.},
  author       = {Gan, Emily Y and Eleftheriadou, Viktoria and Esmat, Samia and Hamzavi, Iltefat and Passeron, Thierry and B{\"o}hm, Markus and Anbar, Tag and Goh, Boon Kee and Lan, Cheng-Che E. and Lui, Harvey and Ramam, M and Raboobee, Noufal and Katayama, Ichiro and Suzuki, Tamio and Parsad, Davinder and Seth, Vaneeta and Lim, Henry W and van Geel, Nanja and Mulekar, Sanjeev and Harris, John and Wittal, Richard and Benzekri, Laila and Gauthier, Yvon and Kumarasinghe, Prasad and Thng, Steven TG and Silva de Castro, Caio Cesar and Abdallah, Marwa and Vrijman, Charlotte and Bekkenk, Marcel and Seneschal, Julien and Pandya, Amit G and Ezzedine, Khaled and Picardo, Mauro and Ta{\"i}eb, Alain},
  issn         = {1755-1471},
  journal      = {PIGMENT CELL \& MELANOMA RESEARCH},
  keyword      = {repigmentation/vitiligo/pigment/repigmentation pattern/outcome measure,EPIDERMAL-CELL SUSPENSION,QUALITY-OF-LIFE,TERM-FOLLOW-UP,MELANOCYTE-STIMULATING HORMONE,HUMAN SEBACEOUS GLANDS,LONG-TERM,WNT/BETA-CATENIN,STEM-CELLS,HUMAN SKIN,UV-B},
  language     = {eng},
  number       = {1},
  pages        = {28--40},
  title        = {Repigmentation in vitiligo : position paper of the Vitiligo Global Issues Consensus Conference},
  url          = {http://dx.doi.org/10.1111/pcmr.12561},
  volume       = {30},
  year         = {2016},
}

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